NADPH oxidase 1 plays a key role in diabetes mellitus–accelerated atherosclerosis SP Gray, E Di Marco, J Okabe, C Szyndralewiez, F Heitz, AC Montezano, ... Circulation 127 (18), 1888-1902, 2013 | 442 | 2013 |
Genetic targeting or pharmacologic inhibition of NADPH oxidase nox4 provides renoprotection in long-term diabetic nephropathy JC Jha, SP Gray, D Barit, J Okabe, A El-Osta, T Namikoshi, ... Journal of the American Society of Nephrology 25 (6), 1237-1254, 2014 | 376 | 2014 |
Compensatory growth of healthy cardiac cells in the presence of diseased cells restores tissue homeostasis during heart development JD Drenckhahn, QP Schwarz, S Gray, A Laskowski, H Kiriazis, Z Ming, ... Developmental cell 15 (4), 521-533, 2008 | 214 | 2008 |
Reactive oxygen species can provide atheroprotection via NOX4-dependent inhibition of inflammation and vascular remodeling SP Gray, E Di Marco, K Kennedy, P Chew, J Okabe, A El-Osta, AC Calkin, ... Arteriosclerosis, thrombosis, and vascular biology 36 (2), 295-307, 2016 | 190 | 2016 |
Protective effect of let-7 miRNA family in regulating inflammation in diabetes-associated atherosclerosis E Brennan, B Wang, A McClelland, M Mohan, M Marai, O Beuscart, ... Diabetes 66 (8), 2266-2277, 2017 | 173 | 2017 |
Targeting the upregulation of reactive oxygen species subsequent to hyperglycemia prevents type 1 diabetic cardiomyopathy in mice K Huynh, H Kiriazis, XJ Du, JE Love, SP Gray, KA Jandeleit-Dahm, ... Free Radical Biology and Medicine 60, 307-317, 2013 | 165 | 2013 |
Podocyte-specific Nox4 deletion affords renoprotection in a mouse model of diabetic nephropathy JC Jha, V Thallas-Bonke, C Banal, SP Gray, BSM Chow, G Ramm, ... Diabetologia 59 (2), 379-389, 2016 | 149 | 2016 |
Prenatal exposure to alcohol reduces nephron number and raises blood pressure in progeny SP Gray, KM Denton, L Cullen-McEwen, JF Bertram, KM Moritz Journal of the American Society of Nephrology 21 (11), 1891-1902, 2010 | 145 | 2010 |
Patient and caregiver outcomes 12 months after home-based therapy for hip fracture: a randomized controlled trial M Crotty, C Whitehead, M Miller, S Gray Archives of physical medicine and rehabilitation 84 (8), 1237-1239, 2003 | 145 | 2003 |
NADPH oxidase Nox5 accelerates renal injury in diabetic nephropathy JC Jha, C Banal, J Okabe, SP Gray, T Hettige, BSM Chow, ... Diabetes 66 (10), 2691-2703, 2017 | 143 | 2017 |
Oxidative stress, Nox isoforms and complications of diabetes—potential targets for novel therapies M Sedeek, AC Montezano, RL Hebert, SP Gray, E Di Marco, JC Jha, ... Journal of cardiovascular translational research 5, 509-518, 2012 | 138 | 2012 |
Nox‐4 deletion reduces oxidative stress and injury by PKC‐α‐associated mechanisms in diabetic nephropathy V Thallas‐Bonke, JC Jha, SP Gray, D Barit, H Haller, HHHW Schmidt, ... Physiological reports 2 (11), e12192, 2014 | 125 | 2014 |
Combined NOX1/4 inhibition with GKT137831 in mice provides dose-dependent reno-and atheroprotection even in established micro-and macrovascular disease SP Gray, JC Jha, K Kennedy, E Van Bommel, P Chew, C Szyndralewiez, ... Diabetologia 60, 927-937, 2017 | 119 | 2017 |
Cardioprotective effect of the mitochondrial unfolded protein response during chronic pressure overload I Smyrnias, SP Gray, DO Okonko, G Sawyer, A Zoccarato, N Catibog, ... Journal of the American College of Cardiology 73 (14), 1795-1806, 2019 | 107 | 2019 |
The pathobiology of diabetic vascular complications—cardiovascular and kidney disease SP Gray, K Jandeleit-Dahm Journal of molecular medicine 92 (5), 441-452, 2014 | 94 | 2014 |
Pharmacological inhibition of NOX reduces atherosclerotic lesions, vascular ROS and immune–inflammatory responses in diabetic Apoe −/− mice E Di Marco, SP Gray, P Chew, C Koulis, A Ziegler, C Szyndralewiez, ... Diabetologia 57, 633-642, 2014 | 82 | 2014 |
Linking RAGE and Nox in diabetic micro-and macrovascular complications C Koulis, AMD Watson, SP Gray, KA Jandeleit-Dahm Diabetes & metabolism 41 (4), 272-281, 2015 | 81 | 2015 |
Alleviating the burden of diabetic nephropathy SP Gray, ME Cooper Nature Reviews Nephrology 7 (2), 71-73, 2011 | 81 | 2011 |
Repeated ethanol exposure during late gestation decreases nephron endowment in fetal sheep SP Gray, K Kenna, JF Bertram, WE Hoy, EB Yan, AD Bocking, JF Brien, ... American Journal of Physiology-Regulatory, Integrative and Comparative …, 2008 | 75 | 2008 |
NOX4-derived reactive oxygen species limit fibrosis and inhibit proliferation of vascular smooth muscle cells in diabetic atherosclerosis E Di Marco, SP Gray, K Kennedy, C Szyndralewiez, AN Lyle, B Lassegue, ... Free Radical Biology and Medicine 97, 556-567, 2016 | 72 | 2016 |