FUS-SMN protein interactions link the motor neuron diseases ALS and SMA T Yamazaki, S Chen, Y Yu, B Yan, TC Haertlein, MA Carrasco, JC Tapia, ... Cell reports 2 (4), 799-806, 2012 | 293 | 2012 |
FUS functions in coupling transcription to splicing by mediating an interaction between RNAP II and U1 snRNP Y Yu, R Reed Proceedings of the National Academy of Sciences 112 (28), 8608-8613, 2015 | 134 | 2015 |
U1 snRNP is mislocalized in ALS patient fibroblasts bearing NLS mutations in FUS and is required for motor neuron outgrowth in zebrafish Y Yu, B Chi, W Xia, J Gangopadhyay, T Yamazaki, ME Winkelbauer-Hurt, ... Nucleic acids research 43 (6), 3208-3218, 2015 | 102 | 2015 |
Copy-number and gene dependency analysis reveals partial copy loss of wild-type SF3B1 as a novel cancer vulnerability BR Paolella, WJ Gibson, LM Urbanski, JA Alberta, TI Zack, ... Elife 6, e23268, 2017 | 81 | 2017 |
The neurodegenerative diseases ALS and SMA are linked at the molecular level via the ASC-1 complex B Chi, JD O’Connell, AD Iocolano, JA Coady, Y Yu, J Gangopadhyay, ... Nucleic acids research 46 (22), 11939-11951, 2018 | 44 | 2018 |
A deep learning approach to identify gene targets of a therapeutic for human splicing disorders D Gao, E Morini, M Salani, AJ Krauson, A Chekuri, N Sharma, ... Nature communications 12 (1), 3332, 2021 | 35 | 2021 |
Primary microRNA processing is functionally coupled to RNAP II transcription in vitro S Yin, Y Yu, R Reed Scientific reports 5 (1), 11992, 2015 | 24 | 2015 |
A model in vitro system for co-transcriptional splicing Y Yu, R Das, EG Folco, R Reed Nucleic acids research 38 (21), 7570-7578, 2010 | 17 | 2010 |
A U2-snRNP–independent role of SF3b in promoting mRNA export K Wang, C Yin, X Du, S Chen, J Wang, L Zhang, L Wang, Y Yu, B Chi, ... Proceedings of the National Academy of Sciences 116 (16), 7837-7846, 2019 | 16 | 2019 |
人类免疫缺陷病毒-1 进入细胞的分子机制及相关药物的研究 余勇, 肖庚富, 李敏, 詹睿, 张文涛 生物化学与生物物理进展 30 (1), 13-18, 2003 | 11 | 2003 |
Flexibility of the Ure2 prion domain is important for amyloid fibril formation Y Yu, HY Wang, M Bai, S Perrett Biochemical Journal 434 (1), 143-151, 2011 | 9 | 2011 |
FUSSMN protein interactions link the motor neuron diseases ALS and SMA. Cell Rep 2: 799–806 T Yamazaki, S Chen, Y Yu, B Yan, TC Haertlein, MA Carrasco, JC Tapia, ... | 7 | 2012 |
Methods of diagnosing and treating amyotrophic lateral sclerosis R Reed, S Chen, Y Yu, T Yamazaki US Patent App. 14/123,392, 2014 | 4 | 2014 |
一种新型多肽类 HIV-1 进入抑制剂 余勇, 黄晓星, 王琼, 杨雅玲, 田波, 张文涛 科学通报 49 (18), 1913-1915, 2004 | 2 | 2004 |
In vitro system for coupling RNAP II transcription to primary microrna processing and a three-way system for RNAP II transcription/splicing/microRNA processing S Yin, A Iocolano, Y Yu, J Gangopadhyay, R Reed miRNA Biogenesis: Methods and Protocols, 43-50, 2018 | 1 | 2018 |