K27M mutation in histone H3. 3 defines clinically and biologically distinct subgroups of pediatric diffuse intrinsic pontine gliomas DA Khuong-Quang, P Buczkowicz, P Rakopoulos, XY Liu, ... Acta neuropathologica 124, 439-447, 2012 | 991 | 2012 |
Genomic analysis of diffuse intrinsic pontine gliomas identifies three molecular subgroups and recurrent activating ACVR1 mutations P Buczkowicz, C Hoeman, P Rakopoulos, S Pajovic, L Letourneau, ... Nature genetics 46 (5), 451-456, 2014 | 639 | 2014 |
Whole-genome profiling of pediatric diffuse intrinsic pontine gliomas highlights platelet-derived growth factor receptor α and poly (ADP-ribose) polymerase as potential … M Zarghooni, U Bartels, E Lee, P Buczkowicz, A Morrison, A Huang, ... Journal of clinical oncology 28 (8), 1337-1344, 2010 | 360 | 2010 |
Histopathological spectrum of paediatric diffuse intrinsic pontine glioma: diagnostic and therapeutic implications P Buczkowicz, U Bartels, E Bouffet, O Becher, C Hawkins Acta neuropathologica 128, 573-581, 2014 | 326 | 2014 |
BRAF Mutation and CDKN2A Deletion Define a Clinically Distinct Subgroup of Childhood Secondary High-Grade Glioma M Mistry, N Zhukova, D Merico, P Rakopoulos, R Krishnatry, M Shago, ... Journal of clinical oncology 33 (9), 1015-1022, 2015 | 297 | 2015 |
Spatial genomic heterogeneity in diffuse intrinsic pontine and midline high-grade glioma: implications for diagnostic biopsy and targeted therapeutics LM Hoffman, M DeWire, S Ryall, P Buczkowicz, J Leach, L Miles, ... Acta neuropathologica communications 4, 1-8, 2016 | 156 | 2016 |
Spatial heterogeneity in medulloblastoma AS Morrissy, FMG Cavalli, M Remke, V Ramaswamy, DJH Shih, ... Nature genetics 49 (5), 780-788, 2017 | 141 | 2017 |
Pathology, molecular genetics, and epigenetics of diffuse intrinsic pontine glioma P Buczkowicz, C Hawkins Frontiers in oncology 5, 147, 2015 | 123 | 2015 |
Targeted detection of genetic alterations reveal the prognostic impact of H3K27M and MAPK pathway aberrations in paediatric thalamic glioma S Ryall, R Krishnatry, A Arnoldo, P Buczkowicz, M Mistry, R Siddaway, ... Acta neuropathologica communications 4, 1-10, 2016 | 113 | 2016 |
ATM regulates 3-methylpurine-DNA glycosylase and promotes therapeutic resistance to alkylating agents S Agnihotri, K Burrell, P Buczkowicz, M Remke, B Golbourn, ... Cancer discovery 4 (10), 1198-1213, 2014 | 81 | 2014 |
Poly-ADP-ribose polymerase as a therapeutic target in pediatric diffuse intrinsic pontine glioma and pediatric high-grade astrocytoma Y Chornenkyy, S Agnihotri, M Yu, P Buczkowicz, P Rakopoulos, ... Molecular cancer therapeutics 14 (11), 2560-2568, 2015 | 66 | 2015 |
Genomic answers for children: Dynamic analyses of> 1000 pediatric rare disease genomes ASA Cohen, EG Farrow, AT Abdelmoity, JT Alaimo, SM Amudhavalli, ... Genetics in Medicine 24 (6), 1336-1348, 2022 | 59 | 2022 |
Alternative lengthening of telomeres is enriched in, and impacts survival of TP53 mutant pediatric malignant brain tumors J Mangerel, A Price, P Castelo-Branco, J Brzezinski, P Buczkowicz, ... Acta neuropathologica 128, 853-862, 2014 | 57 | 2014 |
A urora Kinase B Is a Potential Therapeutic Target in Pediatric Diffuse Intrinsic Pontine Glioma P Buczkowicz, M Zarghooni, U Bartels, A Morrison, KL Misuraca, T Chan, ... Brain pathology 23 (3), 244-253, 2013 | 46 | 2013 |
Telomerase inhibition abolishes the tumorigenicity of pediatric ependymoma tumor-initiating cells M Barszczyk, P Buczkowicz, P Castelo-Branco, SC Mack, V Ramaswamy, ... Acta neuropathologica 128, 863-877, 2014 | 42 | 2014 |
GLI2 is a potential therapeutic target in pediatric medulloblastoma P Buczkowicz, J Ma, C Hawkins Journal of Neuropathology & Experimental Neurology 70 (6), 430-437, 2011 | 33 | 2011 |
Identification of complex genomic rearrangements in cancers using CouGaR M Dzamba, AK Ramani, P Buczkowicz, Y Jiang, M Yu, C Hawkins, ... Genome research 27 (1), 107-117, 2017 | 31 | 2017 |
Practical implications of the updated WHO classification of brain tumors M Martinez-Lage, F Sahm Seminars in Neurology 38 (01), 011-018, 2018 | 10 | 2018 |
Abstract B12: H3-K27M is a negative prognostic marker in high-and low-grade pediatric thalamic glioma S Ryall, P Buczkowicz, A Arnoldo, R Krishnatry, M Mistry, J Rubin, ... Cancer Research 76 (2_Supplement), B12-B12, 2016 | 1 | 2016 |
Comprehensive Integrated Genomic and Histopathological Analysis of Paediatric Diffuse Intrinsic Pontine Glioma P Buczkowicz University of Toronto (Canada), 2014 | 1 | 2014 |