CD22-targeted CAR T cells induce remission in B-ALL that is naive or resistant to CD19-targeted CAR immunotherapy TJ Fry, NN Shah, RJ Orentas, M Stetler-Stevenson, CM Yuan, ... Nature medicine 24 (1), 20-28, 2018 | 1299 | 2018 |
Human CAR T cells with cell-intrinsic PD-1 checkpoint blockade resist tumor-mediated inhibition L Cherkassky, A Morello, J Villena-Vargas, Y Feng, DS Dimitrov, ... The Journal of clinical investigation 126 (8), 3130-3144, 2016 | 984 | 2016 |
Potent cross-reactive neutralization of SARS coronavirus isolates by human monoclonal antibodies Z Zhu, S Chakraborti, Y He, A Roberts, T Sheahan, X Xiao, LE Hensley, ... Proceedings of the National Academy of Sciences 104 (29), 12123-12128, 2007 | 359 | 2007 |
Eradication of tumors through simultaneous ablation of CD276/B7-H3-positive tumor cells and tumor vasculature S Seaman, Z Zhu, S Saha, XM Zhang, MY Yang, MB Hilton, K Morris, ... Cancer cell 31 (4), 501-515. e8, 2017 | 338 | 2017 |
Germline-like predecessors of broadly neutralizing antibodies lack measurable binding to HIV-1 envelope glycoproteins: implications for evasion of immune responses and design … X Xiao, W Chen, Y Feng, Z Zhu, P Prabakaran, Y Wang, MY Zhang, ... Biochemical and biophysical research communications 390 (3), 404-409, 2009 | 329 | 2009 |
Structure of severe acute respiratory syndrome coronavirus receptor-binding domain complexed with neutralizing antibody P Prabakaran, J Gan, Y Feng, Z Zhu, V Choudhry, X Xiao, X Ji, ... Journal of Biological Chemistry 281 (23), 15829-15836, 2006 | 287 | 2006 |
Exceptionally potent neutralization of Middle East respiratory syndrome coronavirus by human monoclonal antibodies T Ying, L Du, TW Ju, P Prabakaran, CCY Lau, L Lu, Q Liu, L Wang, ... Journal of virology 88 (14), 7796-7805, 2014 | 278 | 2014 |
Potent neutralization of Hendra and Nipah viruses by human monoclonal antibodies Z Zhu, AS Dimitrov, KN Bossart, G Crameri, KA Bishop, V Choudhry, ... Journal of virology 80 (2), 891-899, 2006 | 199 | 2006 |
Targeting of folate receptor β on acute myeloid leukemia blasts with chimeric antigen receptor–expressing T cells RC Lynn, M Poussin, A Kalota, Y Feng, PS Low, DS Dimitrov, ... Blood, The Journal of the American Society of Hematology 125 (22), 3466-3476, 2015 | 197 | 2015 |
Identification of GPC2 as an oncoprotein and candidate immunotherapeutic target in high-risk neuroblastoma KR Bosse, P Raman, Z Zhu, M Lane, D Martinez, S Heitzeneder, KS Rathi, ... Cancer cell 32 (3), 295-309. e12, 2017 | 184 | 2017 |
Exceptionally potent cross-reactive neutralization of Nipah and Hendra viruses by a human monoclonal antibody Z Zhu, KN Bossart, KA Bishop, G Crameri, AS Dimitrov, JA McEachern, ... The Journal of infectious diseases 197 (6), 846-853, 2008 | 184 | 2008 |
Modulation of target antigen density improves CAR T-cell functionality and persistence S Ramakrishna, SL Highfill, Z Walsh, SM Nguyen, H Lei, JF Shern, H Qin, ... Clinical Cancer Research 25 (17), 5329-5341, 2019 | 149 | 2019 |
Polo-like kinase is required for the fragmentation of pericentriolar Golgi stacks during mitosis C Sütterlin, CY Lin, Y Feng, DK Ferris, RL Erikson, V Malhotra Proceedings of the National Academy of Sciences 98 (16), 9128-9132, 2001 | 143 | 2001 |
High-affinity FRβ-specific CAR T cells eradicate AML and normal myeloid lineage without HSC toxicity RC Lynn, Y Feng, K Schutsky, M Poussin, A Kalota, DS Dimitrov, ... Leukemia 30 (6), 1355-1364, 2016 | 139 | 2016 |
Antibody aggregation: insights from sequence and structure W Li, P Prabakaran, W Chen, Z Zhu, Y Feng, DS Dimitrov Antibodies 5 (3), 19, 2016 | 136 | 2016 |
Identification of a putative Crimean-Congo hemorrhagic fever virus entry factor X Xiao, Y Feng, Z Zhu, DS Dimitrov Biochemical and biophysical research communications 411 (2), 253-258, 2011 | 128 | 2011 |
Junctional and allele-specific residues are critical for MERS-CoV neutralization by an exceptionally potent germline-like antibody T Ying, P Prabakaran, L Du, W Shi, Y Feng, Y Wang, L Wang, W Li, ... Nature communications 6 (1), 8223, 2015 | 125 | 2015 |
Engineered human antibody constant domains with increased stability R Gong, BK Vu, Y Feng, DRA Prieto, MA Dyba, JD Walsh, P Prabakaran, ... Journal of Biological Chemistry 284 (21), 14203-14210, 2009 | 113 | 2009 |
Human domain antibodies to conserved sterically restricted regions on gp120 as exceptionally potent cross-reactive HIV-1 neutralizers W Chen, Z Zhu, Y Feng, DS Dimitrov Proceedings of the National Academy of Sciences 105 (44), 17121-17126, 2008 | 110 | 2008 |
Novel human monoclonal antibodies to insulin-like growth factor (IGF)-II that potently inhibit the IGF receptor type I signal transduction function Y Feng, Z Zhu, X Xiao, V Choudhry, JC Barrett, DS Dimitrov Molecular cancer therapeutics 5 (1), 114-120, 2006 | 110 | 2006 |