| Cytokeratins mediate epithelial innate defense through their antimicrobial properties C Tam, JJ Mun, DJ Evans, SMJ Fleiszig The Journal of clinical investigation 122 (10), 3665-3677, 2012 | 156 | 2012 |
| Factors impacting corneal epithelial barrier function against Pseudomonas aeruginosa traversal I Alarcon, C Tam, JJ Mun, J LeDue, DJ Evans, SMJ Fleiszig Investigative ophthalmology & visual science 52 (3), 1368-1377, 2011 | 95 | 2011 |
| Clearance of Pseudomonas aeruginosa from a Healthy Ocular Surface Involves Surfactant Protein D and Is Compromised by Bacterial Elastase in a Murine Null … JJ Mun, C Tam, D Kowbel, S Hawgood, MJ Barnett, DJ Evans, ... Infection and immunity 77 (6), 2392-2398, 2009 | 86 | 2009 |
| Role of Defensins in Corneal Epithelial Barrier Function against Pseudomonas aeruginosa Traversal DK Augustin, SR Heimer, C Tam, WY Li, JM Le Due, DJ Evans, ... Infection and immunity 79 (2), 595-605, 2011 | 80 | 2011 |
| The impact of inoculation parameters on the pathogenesis of contact lens–related infectious keratitis C Tam, JJ Mun, DJ Evans, SMJ Fleiszig Investigative ophthalmology & visual science 51 (6), 3100-3106, 2010 | 80 | 2010 |
| Association between cytotoxic and invasive Pseudomonas aeruginosa and clinical outcomes in bacterial keratitis DS Borkar, SMJ Fleiszig, C Leong, P Lalitha, M Srinivasan, AA Ghanekar, ... JAMA ophthalmology 131 (2), 147-153, 2013 | 72 | 2013 |
| MicroRNA-762 is upregulated in human corneal epithelial cells in response to tear fluid and Pseudomonas aeruginosa antigens and negatively regulates the expression of host … J Mun, C Tam, G Chan, JH Kim, D Evans, S Fleiszig PloS one 8 (2), e57850, 2013 | 52 | 2013 |
| Adenylate cyclase activity of Pseudomonas aeruginosa ExoY can mediate bleb-niche formation in epithelial cells and contributes to virulence V Hritonenko, JJ Mun, C Tam, NC Simon, JT Barbieri, DJ Evans, ... Microbial pathogenesis 51 (5), 305-312, 2011 | 46 | 2011 |
| 3D quantitative imaging of unprocessed live tissue reveals epithelial defense against bacterial adhesion and subsequent traversal requires MyD88 C Tam, J LeDue, JJ Mun, P Herzmark, EA Robey, DJ Evans, SMJ Fleiszig PLoS One 6 (8), e24008, 2011 | 41 | 2011 |
| Salmonella enterica serovar Dublin strains which are Vi antigen-positive use type IVB pili for bacterial self-association and human intestinal cell entry C Morris, CKP Tam, TS Wallis, PW Jones, J Hackett Microbial pathogenesis 35 (6), 279-284, 2003 | 41 | 2003 |
| Mutation of the phospholipase catalytic domain of the Pseudomonas aeruginosa cytotoxin ExoU abolishes colonization promoting activity and reduces corneal disease severity C Tam, SE Lewis, WY Li, E Lee, DJ Evans, SMJ Fleiszig Experimental eye research 85 (6), 799-805, 2007 | 39 | 2007 |
| Modulation of epithelial immunity by mucosal fluid JJ Mun, C Tam, DJ Evans, SMJ Fleiszig Scientific reports 1 (1), 8, 2011 | 36 | 2011 |
| Expression of surfactant protein D in human corneal epithelial cells is upregulated by Pseudomonas aeruginosa M Ni, C Tam, A Verma, R Ramphal, S Hawgood, DJ Evans, SMJ Fleiszig FEMS Immunology & Medical Microbiology 54 (2), 177-184, 2008 | 30 | 2008 |
| Topical tacrolimus nanocapsules eye drops for therapeutic effect enhancement in both anterior and posterior ocular inflammation models L Rebibo, C Tam, Y Sun, E Shoshani, A Badihi, T Nassar, S Benita Journal of Controlled Release 333, 283-297, 2021 | 29 | 2021 |
| Traversal of multilayered corneal epithelia by cytotoxic Pseudomonas aeruginosa requires the phospholipase domain of exoU JC Ramirez, SMJ Fleiszig, AB Sullivan, C Tam, R Borazjani, DJ Evans Investigative ophthalmology & visual science 53 (1), 448-453, 2012 | 26 | 2012 |
| A novel murine model for contact lens wear reveals clandestine IL-1R dependent corneal parainflammation and susceptibility to microbial keratitis upon inoculation with … MME Metruccio, SJ Wan, H Horneman, AR Kroken, AB Sullivan, ... The ocular surface 17 (1), 119-133, 2019 | 25 | 2019 |
| Keratin 6a reorganization for ubiquitin–proteasomal processing is a direct antimicrobial response JKL Chan, D Yuen, PHM Too, Y Sun, B Willard, D Man, C Tam Journal of Cell Biology 217 (2), 731-744, 2018 | 24 | 2018 |
| Contributions of MyD88-dependent receptors and CD11c-positive cells to corneal epithelial barrier function against Pseudomonas aeruginosa MME Metruccio, C Tam, DJ Evans, AL Xie, ME Stern, SMJ Fleiszig Scientific reports 7 (1), 13829, 2017 | 23 | 2017 |
| Membrane-active epithelial keratin 6A fragments (KAMPs) are unique human antimicrobial peptides with a non-αβ structure JTY Lee, G Wang, YT Tam, C Tam Frontiers in microbiology 7, 1799, 2016 | 20 | 2016 |
| Salmonella enterica Serovar Paratyphi C Carries an Inactive Shufflon CKP Tam, J Hackett, C Morris Infection and immunity 72 (1), 22-28, 2004 | 16 | 2004 |
