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The crystal structures of severe acute respiratory syndrome virus main protease and its complex with an inhibitor H Yang, M Yang, Y Ding, Y Liu, Z Lou, Z Zhou, L Sun, L Mo, S Ye, H Pang, ... Proceedings of the National Academy of Sciences 100 (23), 13190-13195, 2003 | 1112 | 2003 |
Crystal structure of mitochondrial respiratory membrane protein complex II F Sun, X Huo, Y Zhai, A Wang, J Xu, D Su, M Bartlam, Z Rao Cell 121 (7), 1043-1057, 2005 | 980 | 2005 |
Design of wide-spectrum inhibitors targeting coronavirus main proteases H Yang, W Xie, X Xue, K Yang, J Ma, W Liang, Q Zhao, Z Zhou, D Pei, ... PLoS biology 3 (10), e324, 2005 | 737 | 2005 |
Crystal structure of an avian influenza polymerase PAN reveals an endonuclease active site P Yuan, M Bartlam, Z Lou, S Chen, J Zhou, X He, Z Lv, R Ge, X Li, T Deng, ... Nature 458 (7240), 909-913, 2009 | 634 | 2009 |
Selective enrichment of bacterial pathogens by microplastic biofilm X Wu, J Pan, M Li, Y Li, M Bartlam, Y Wang Water research 165, 114979, 2019 | 523 | 2019 |
Structures of two coronavirus main proteases: implications for substrate binding and antiviral drug design X Xue, H Yu, H Yang, F Xue, Z Wu, W Shen, J Li, Z Zhou, Y Ding, Q Zhao, ... Journal of virology 82 (5), 2515-2527, 2008 | 454 | 2008 |
Insights into SARS-CoV transcription and replication from the structure of the nsp7–nsp8 hexadecamer Y Zhai, F Sun, X Li, H Pang, X Xu, M Bartlam, Z Rao Nature structural & molecular biology 12 (11), 980-986, 2005 | 367 | 2005 |
Crystal structure of the polymerase PAC–PB1N complex from an avian influenza H5N1 virus X He, J Zhou, M Bartlam, R Zhang, J Ma, Z Lou, X Li, J Li, A Joachimiak, ... Nature 454 (7208), 1123-1126, 2008 | 358 | 2008 |
Production of authentic SARS-CoV Mpro with enhanced activity: application as a novel tag-cleavage endopeptidase for protein overproduction X Xue, H Yang, W Shen, Q Zhao, J Li, K Yang, C Chen, Y Jin, M Bartlam, ... Journal of molecular biology 366 (3), 965-975, 2007 | 248 | 2007 |
3D structure of human FK506-binding protein 52: implications for the assembly of the glucocorticoid receptor/Hsp90/immunophilin heterocomplex B Wu, P Li, Y Liu, Z Lou, Y Ding, C Shu, S Ye, M Bartlam, B Shen, Z Rao Proceedings of the National Academy of Sciences 101 (22), 8348-8353, 2004 | 222 | 2004 |
Crystal structure of long-chain alkane monooxygenase (LadA) in complex with coenzyme FMN: unveiling the long-chain alkane hydroxylase L Li, X Liu, W Yang, F Xu, W Wang, L Feng, M Bartlam, L Wang, Z Rao Journal of molecular biology 376 (2), 453-465, 2008 | 221 | 2008 |
New insights into the structural characteristics and functional relevance of the human cytochrome P450 2D6 enzyme B Wang, LP Yang, XZ Zhang, SQ Huang, M Bartlam, SF Zhou Drug metabolism reviews 41 (4), 573-643, 2009 | 219 | 2009 |
Structural insights into diversity and n-alkane biodegradation mechanisms of alkane hydroxylases Y Ji, G Mao, Y Wang, M Bartlam Frontiers in microbiology 4, 58, 2013 | 218 | 2013 |
Drug design targeting the main protease, the Achilles' heel of coronaviruses H Yang, M Bartlam, Z Rao Current pharmaceutical design 12 (35), 4573-4590, 2006 | 206 | 2006 |
An insight into the mechanism of human cysteine dioxygenase: key roles of the thioether-bonded tyrosine-cysteine cofactor S Ye, L Wei, D Tang, P Sun, M Bartlam, Z Rao Journal of Biological Chemistry 282 (5), 3391-3402, 2007 | 190 | 2007 |
Crystal structure of methyl parathion hydrolase from Pseudomonas sp. WBC-3 YJ Dong, M Bartlam, L Sun, YF Zhou, ZP Zhang, CG Zhang, Z Rao, ... Journal of molecular biology 353 (3), 655-663, 2005 | 180 | 2005 |
Crystal structure of alanine: glyoxylate aminotransferase and the relationship between genotype and enzymatic phenotype in primary hyperoxaluria type 1 X Zhang, SM Roe, Y Hou, M Bartlam, Z Rao, LH Pearl, CJ Danpure Journal of molecular biology 331 (3), 643-652, 2003 | 160 | 2003 |
Dodecamer structure of severe acute respiratory syndrome coronavirus nonstructural protein nsp10 D Su, Z Lou, F Sun, Y Zhai, H Yang, R Zhang, A Joachimiak, XC Zhang, ... Journal of virology 80 (16), 7902-7908, 2006 | 133 | 2006 |
Crystal structure of human pirin: an iron-binding nuclear protein and transcription cofactor H Pang, M Bartlam, Q Zeng, H Miyatake, T Hisano, K Miki, LL Wong, ... Journal of Biological Chemistry 279 (2), 1491-1498, 2004 | 125 | 2004 |