Cytochrome P450-mediated drug interactions in COVID-19 patients: Current findings and possible mechanisms MA El-Ghiaty, SM Shoieb, AOS El-Kadi Medical hypotheses 144, 110033, 2020 | 47 | 2020 |
The duality of arsenic metabolism: impact on human health MA El-Ghiaty, AOS El-Kadi Annual review of pharmacology and toxicology 63 (1), 341-358, 2023 | 38 | 2023 |
Cytochrome P450-derived eicosanoids and inflammation in liver diseases SM Shoieb, MA El-Ghiaty, MA Alqahtani, AOS El-Kadi Prostaglandins & other lipid mediators 147, 106400, 2020 | 32 | 2020 |
Targeting arachidonic acid–related metabolites in COVID-19 patients: potential use of drug-loaded nanoparticles SM Shoieb, MA El-Ghiaty, AOS El-Kadi Emergent materials 4 (1), 265-277, 2021 | 24 | 2021 |
Evaluation of the protective effect of Cystone® against cisplatin-induced nephrotoxicity in cancer patients, and its influence on cisplatin antitumor activity MA El-Ghiaty, OMH Ibrahim, SM Abdou, FZ Hussein International urology and nephrology 46, 1367-1373, 2014 | 22 | 2014 |
Arsenic: Various species with different effects on cytochrome P450 regulation in humans MA El-Ghiaty, AOS El-Kadi EXCLI journal 20, 1184, 2021 | 21 | 2021 |
Down-regulation of hepatic cytochromes P450 1A1 and 1A2 by arsenic trioxide (ATO) in vivo and in vitro: A role of heme oxygenase 1 MA El-Ghiaty, MA Alqahtani, AOS El-Kadi Chemico-Biological Interactions 364, 110049, 2022 | 13 | 2022 |
Modulation of cytochrome P450 1A (CYP1A) enzymes by monomethylmonothioarsonic acid (MMMTAV) in vivo and in vitro MA El-Ghiaty, MA Alqahtani, AOS El-Kadi Chemico-Biological Interactions 376, 110447, 2023 | 9 | 2023 |
Mercury and methylmercury differentially modulate hepatic cytochrome P450 1A1 and 1A2 in vivo and in vitro MA Alqahtani, MA El‐Ghiaty, AOS El‐Kadi Journal of Biochemical and Molecular Toxicology 37 (2), e23243, 2023 | 9 | 2023 |
Arsenic trioxide (ATO) up-regulates cytochrome P450 1A (CYP1A) enzymes in murine hepatoma Hepa-1c1c7 cell line MA El-Ghiaty, MA Alqahtani, AOS El-Kadi Environmental Toxicology and Pharmacology 101, 104214, 2023 | 5 | 2023 |
Differential modulation of cytochrome P450 enzymes by arsenicals in non-human experimental models MA El-Ghiaty, SR El-Mahrouk, MA Alqahtani, AOS El-Kadi Drug Metabolism Reviews 55 (4), 405-427, 2023 | 4 | 2023 |
Methylmercury (MeHg) transcriptionally regulates NAD (P) H: quinone oxidoreductase 1 (NQO1) in Hepa-1c1c7 cells MA Alqahtani, MA El-Ghiaty, SR El-Mahrouk, AOS El-Kadi Current Research in Toxicology 5, 100126, 2023 | 2 | 2023 |
Identifying novel aryl hydrocarbon receptor (AhR) modulators from clinically approved drugs: In silico screening and In vitro validation FES Mosa, MA Alqahtani, MA El-Ghiaty, K Barakat, AOS El-Kadi Archives of Biochemistry and Biophysics 754, 109958, 2024 | 1 | 2024 |
The role of nuclear factor erythroid 2-related factor 2 (NRF2) in arsenic toxicity SR El-Mahrouk, MA El-Ghiaty, AOS El-Kadi Journal of Environmental Sciences, 2024 | 1 | 2024 |
Sex-and enantiospecific differences in the formation rate of hydroxyeicosatetraenoic acids in rat organs SH Gerges, AH Alammari, MA El-Ghiaty, FA Isse, AOS El-Kadi Canadian Journal of Physiology and Pharmacology 101 (8), 425-436, 2023 | 1 | 2023 |
Identification of aryl hydrocarbon receptor allosteric antagonists from clinically approved drugs FES Mosa, MA Alqahtani, MA El‐Ghiaty, JRB Dyck, K Barakat, ... Drug Development Research 85 (5), e22232, 2024 | | 2024 |
Modulation of Aryl Hydrocarbon Receptor Activity by Tyrosine Kinase Inhibitors (Ponatinib and Tofacitinib) FES Mosa, MA Alqahtani, MA El-Ghiaty, SR El-Mahrouk, K Barakat, ... Archives of Biochemistry and Biophysics, 110088, 2024 | | 2024 |
Alteration of Hepatic Cytochrome P450 Expression and Arachidonic Acid Metabolism by Arsenic Trioxide (ATO) in C57BL/6 Mice MA El-Ghiaty, MA Alqahtani, SR El-Mahrouk, FA Isse, AH Alammari, ... Biological Trace Element Research, 1-16, 2024 | | 2024 |
Dimethylmonothioarsinic acid (DMMTAV) differentially modulates the expression of AHR-regulated cytochrome P450 1A enzymes in vivo and in vitro SR El-Mahrouk, MA El-Ghiaty, MA Alqahtani, AOS El-Kadi Toxicology Letters 394, 32-45, 2024 | | 2024 |
Differential Modulatory Effects of Methylmercury (MeHg) on Ahr-regulated Genes in Extrahepatic Tissues of C57BL/6 Mice MA Alqahtani, MA El-Ghiaty, SR El-Mahrouk, AOS El-Kadi Biological Trace Element Research, 1-10, 2024 | | 2024 |