Antitumor effects of hyaluronic acid inhibitor 4-methylumbelliferone in an orthotopic hepatocellular carcinoma model in mice F Piccioni, M Malvicini, MG Garcia, A Rodriguez, C Atorrasagasti, ... Glycobiology 22 (3), 400-410, 2012 | 127 | 2012 |
Inhibition of NF-κB activity by BAY 11-7082 increases apoptosis in multidrug resistant leukemic T-cell lines MG García, L Alaniz, EC Lopes, G Blanco, SE Hajos, E Alvarez Leukemia research 29 (12), 1425-1434, 2005 | 118 | 2005 |
PI3K/Akt inhibition modulates multidrug resistance and activates NF-κB in murine lymphoma cell lines MG García, LD Alaniz, RIC Russo, E Alvarez, SE Hajos Leukemia research 33 (2), 288-296, 2009 | 115 | 2009 |
Proteoglycans and glycosaminoglycans as regulators of cancer stem cell function and therapeutic resistance D Vitale, S Kumar Katakam, B Greve, B Jang, ES Oh, L Alaniz, M Götte The FEBS Journal 286 (15), 2870-2882, 2019 | 106 | 2019 |
Hyaluronan oligosaccharides sensitize lymphoma resistant cell lines to vincristine by modulating P‐glycoprotein activity and PI3K/Akt pathway RI Cordo Russo, MG García, L Alaniz, G Blanco, E Alvarez, SE Hajos International journal of cancer 122 (5), 1012-1018, 2008 | 96 | 2008 |
Mesenchymal stromal cells engineered to produce IGF-I by recombinant adenovirus ameliorate liver fibrosis in mice EJ Fiore, JM Bayo, MG Garcia, M Malvicini, R Lloyd, F Piccioni, M Rizzo, ... Stem cells and development 24 (6), 791-801, 2015 | 90 | 2015 |
Hepatocellular Carcinoma Cells and Their Fibrotic Microenvironment Modulate Bone Marrow-Derived Mesenchymal Stromal Cell Migration in Vitro and in Vivo MG Garcia, J Bayo, MF Bolontrade, L Sganga, M Malvicini, L Alaniz, ... Molecular pharmaceutics 8 (5), 1538-1548, 2011 | 73 | 2011 |
Low molecular weight hyaluronan inhibits colorectal carcinoma growth by decreasing tumor cell proliferation and stimulating immune response L Alaniz, M Rizzo, M Malvicini, J Jaunarena, D Avella, C Atorrasagasti, ... Cancer letters 278 (1), 9-16, 2009 | 73 | 2009 |
Lack of the matricellular protein SPARC (secreted protein, acidic and rich in cysteine) attenuates liver fibrogenesis in mice C Atorrasagasti, E Peixoto, JB Aquino, N Kippes, M Malvicini, L Alaniz, ... PloS one 8 (2), e54962, 2013 | 69 | 2013 |
Adenovirus‐mediated inhibition of SPARC attenuates liver fibrosis in rats AM Camino, C Atorrasagasti, D Maccio, F Prada, E Salvatierra, M Rizzo, ... The journal of gene medicine 10 (9), 993-1004, 2008 | 68 | 2008 |
Overexpression of SPARC obliterates the in vivo tumorigenicity of human hepatocellular carcinoma cells C Atorrasagasti, M Malvicini, JB Aquino, L Alaniz, M Garcia, M Bolontrade, ... International journal of cancer 126 (11), 2726-2740, 2010 | 66 | 2010 |
Interaction of CD44 with different forms of hyaluronic acid. Its role in adhesion and migration of tumor cells L Alaniz, PV Cabrera, G Blanco, G Ernst, G Rimoldi, E Alvarez, SE Hajos Cell communication & adhesion 9 (3), 117-130, 2002 | 64 | 2002 |
4-methylumbelliferone inhibits hepatocellular carcinoma growth by decreasing IL-6 production and angiogenesis F Piccioni, E Fiore, J Bayo, C Atorrasagasti, E Peixoto, M Rizzo, ... Glycobiology 25 (8), 825-835, 2015 | 62 | 2015 |
The immunological effect of hyaluronan in tumor angiogenesis FM Spinelli, DL Vitale, G Demarchi, C Cristina, L Alaniz Clinical & translational immunology 4 (12), e52, 2015 | 60 | 2015 |
SPARC downregulation attenuates the profibrogenic response of hepatic stellate cells induced by TGF-β1 and PDGF C Atorrasagasti, JB Aquino, L Hofman, L Alaniz, M Malvicini, M Garcia, ... American Journal of Physiology-Gastrointestinal and Liver Physiology 300 (5 …, 2011 | 58 | 2011 |
Sirtuin 1 reduces hyaluronan synthase 2 expression by inhibiting nuclear translocation of NF-κB and expression of the long-noncoding RNA HAS2–AS1 I Caon, B Bartolini, P Moretto, A Parnigoni, E Caravà, DL Vitale, L Alaniz, ... Journal of Biological Chemistry 295 (11), 3485-3496, 2020 | 56 | 2020 |
A novel synergistic combination of cyclophosphamide and gene transfer of interleukin-12 eradicates colorectal carcinoma in mice M Malvicini, M Rizzo, L Alaniz, F Piñero, M García, C Atorrasagasti, ... Clinical Cancer Research 15 (23), 7256-7265, 2009 | 54 | 2009 |
Increased migration of human mesenchymal stromal cells by autocrine motility factor (AMF) resulted in enhanced recruitment towards hepatocellular carcinoma J Bayo, E Fiore, JB Aquino, M Malvicini, M Rizzo, E Peixoto, O Andriani, ... PloS one 9 (4), e95171, 2014 | 52 | 2014 |
Immunotherapy for liver tumors: present status and future prospects P Matar, L Alaniz, V Rozados, JB Aquino, M Malvicini, C Atorrasagasti, ... Journal of biomedical science 16, 1-18, 2009 | 46 | 2009 |
Hyaluronan in the tumor microenvironment FM Spinelli, DL Vitale, I Sevic, L Alaniz Tumor Microenvironment: Extracellular Matrix Components–Part A, 67-83, 2020 | 44 | 2020 |