关注
Eric S. Wang
Eric S. Wang
Sanford Burnham Prebys Medical Discovery Institute
在 sbpdiscovery.org 的电子邮件经过验证
标题
引用次数
引用次数
年份
IRE1α cleaves select microRNAs during ER stress to derepress translation of proapoptotic Caspase-2
JP Upton, L Wang, D Han, ES Wang, NE Huskey, L Lim, M Truitt, ...
Science 338 (6108), 818-822, 2012
7212012
CDK4/6 inhibition augments antitumor immunity by enhancing T-cell activation
J Deng, ES Wang, RW Jenkins, S Li, R Dries, K Yates, S Chhabra, ...
Cancer discovery 8 (2), 216-233, 2018
6052018
Allosteric inhibition of the IRE1α RNase preserves cell viability and function during endoplasmic reticulum stress
R Ghosh, L Wang, ES Wang, BGK Perera, A Igbaria, S Morita, K Prado, ...
Cell 158 (3), 534-548, 2014
4842014
Ex Vivo Profiling of PD-1 Blockade Using Organotypic Tumor Spheroids
RW Jenkins, AR Aref, PH Lizotte, E Ivanova, S Stinson, CW Zhou, ...
Cancer discovery 8 (2), 196-215, 2018
4602018
Development of dual and selective degraders of cyclin‐dependent kinases 4 and 6
B Jiang, ES Wang, KA Donovan, Y Liang, ES Fischer, T Zhang, NS Gray
Angewandte Chemie International Edition 58 (19), 6321-6326, 2019
2152019
Homolog-Selective Degradation as a Strategy to Probe the Function of CDK6 in AML
M Brand, B Jiang, S Bauer, KA Donovan, Y Liang, ES Wang, RP Nowak, ...
Cell chemical biology 26 (2), 300-306. e9, 2019
2112019
CDK7 inhibition potentiates genome instability triggering anti-tumor immunity in small cell lung cancer
H Zhang, CL Christensen, R Dries, MG Oser, J Deng, B Diskin, F Li, Y Pan, ...
Cancer cell 37 (1), 37-54. e9, 2020
1752020
Bruton tyrosine kinase degradation as a therapeutic strategy for cancer
D Dobrovolsky, ES Wang, S Morrow, C Leahy, T Faust, RP Nowak, ...
Blood, The Journal of the American Society of Hematology 133 (9), 952-961, 2019
1542019
Development of highly potent and selective steroidal inhibitors and degraders of CDK8
JM Hatcher, ES Wang, L Johannessen, N Kwiatkowski, T Sim, NS Gray
ACS medicinal chemistry letters 9 (6), 540-545, 2018
872018
ULK1 inhibition overcomes compromised antigen presentation and restores antitumor immunity in LKB1-mutant lung cancer
J Deng, A Thennavan, I Dolgalev, T Chen, J Li, A Marzio, JT Poirier, ...
Nature cancer 2 (5), 503-514, 2021
812021
Inhibition of CDK4/6 promotes CD8 T-cell memory formation
M Heckler, LR Ali, E Clancy-Thompson, L Qiang, KS Ventre, P Lenehan, ...
Cancer discovery 11 (10), 2564-2581, 2021
782021
Acute pharmacological degradation of Helios destabilizes regulatory T cells
ES Wang, AL Verano, RP Nowak, JC Yuan, KA Donovan, NA Eleuteri, ...
Nature chemical biology 17 (6), 711-717, 2021
652021
Selective degradation of GSPT1 by cereblon modulators identified via a focused combinatorial library
CE Powell, G Du, J Che, Z He, KA Donovan, H Yue, ES Wang, RP Nowak, ...
ACS chemical biology 15 (10), 2722-2730, 2020
632020
Fas-activated mitochondrial apoptosis culls stalled embryonic stem cells to promote differentiation
ES Wang, NA Reyes, C Melton, NE Huskey, O Momcilovic, A Goga, ...
Current Biology 25 (23), 3110-3118, 2015
252015
PSGL-1 attenuates early TCR signaling to suppress CD8+ T cell progenitor differentiation and elicit terminal CD8+ T cell exhaustion
JL Hope, DC Otero, EA Bae, CJ Stairiker, AB Palete, HA Faso, M Lin, ...
Cell reports 42 (5), 2023
102023
Reexamination of the cysteine residues in glucocerebrosidase
R Moharram, D Maynard, ES Wang, A Makusky, GJ Murray, BM Martin
FEBS letters 580 (14), 3391-3394, 2006
102006
Acute pharmacological degradation of ERK5 does not inhibit cellular immune response or proliferation
I You, KA Donovan, NM Krupnick, AS Boghossian, MG Rees, MM Ronan, ...
Cell chemical biology 29 (11), 1630-1638. e7, 2022
92022
Development of highly potent and selective pyrazolopyridine inhibitor of CDK8/19
JM Hatcher, PS Vatsan, E Wang, J Jiang, NS Gray
ACS Medicinal Chemistry Letters 12 (11), 1689-1693, 2021
82021
Degradation of cyclin-dependent kinase 4/6 (CDK4/6) by conjugation of CDK4/6 inhibitors with E3 ligase ligand and methods of use
NS Gray, T Zhang, CM Olson, Y Liang, N Kwiatkowski, B Jiang, E Wang
US Patent 10,865,204, 2020
82020
Development of potent and selective degraders of PI5P4Kγ
W Ji, ES Wang, TD Manz, J Jiang, KA Donovan, X Abulaiti, ES Fischer, ...
European journal of medicinal chemistry 247, 115027, 2023
52023
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