Histone H3. 3G34-mutant interneuron progenitors co-opt PDGFRA for gliomagenesis CCL Chen, S Deshmukh, S Jessa, D Hadjadj, V Lisi, AF Andrade, D Faury, ... Cell 183 (6), 1617-1633. e22, 2020 | 118 | 2020 |
Inhibition of Ataxia-Telangiectasia Mutated and RAD3-Related (ATR) Overcomes Oxaliplatin Resistance and Promotes Antitumor Immunity in Colorectal Cancer E Combès, AF Andrade, D Tosi, HA Michaud, F Coquel, V Garambois, ... Cancer Research 79 (11), 2933-2946, 2019 | 56 | 2019 |
Purification and Biochemical Characterization of Native and Pegylated Form of L-Asparaginase from Aspergillus terreus and Evaluation of Its Antiproliferative Activity CB Loureiro, KS Borges, AF Andrade, LG Tone, S Said Scientific Research Publishing, 2012 | 51 | 2012 |
K27M in canonical and noncanonical H3 variants occurs in distinct oligodendroglial cell lineages in brain midline gliomas S Jessa, A Mohammadnia, AS Harutyunyan, M Hulswit, S Varadharajan, ... Nature genetics 54 (12), 1865-1880, 2022 | 43 | 2022 |
Update on the Use of l-Asparaginase in Infants and Adolescent Patients with Acute Lymphoblastic Leukemia AF Andrade, KS Borges, VS Silveira | 41 | 2014 |
Zebularine induces chemosensitization to methotrexate and efficiently decreases AhR gene methylation in childhood acute lymphoblastic leukemia cells AF Andrade, KS Borges, AM Castro-Gamero, VS Silveira, VK Suazo, ... Anti-Cancer Drugs 25 (1), 72-81, 2014 | 31 | 2014 |
The DNA methyltransferase inhibitor zebularine exerts antitumor effects and reveals BATF2 as a poor prognostic marker for childhood medulloblastoma AF Andrade, KS Borges, VK Suazo, L Geron, CAP Corrêa, ... Investigational new drugs 35, 26-36, 2017 | 28 | 2017 |
Single substitution in H3. 3G34 alters DNMT3A recruitment to cause progressive neurodegeneration S Khazaei, CCL Chen, AF Andrade, N Kabir, P Azarafshar, SM Morcos, ... Cell 186 (6), 1162-1178. e20, 2023 | 24 | 2023 |
The aurora kinase inhibitor AMG 900 increases apoptosis and induces chemosensitivity to anticancer drugs in the NCI-H295 adrenocortical carcinoma cell line KS Borges, AF Andrade, VS Silveira, DSM Antonio, EJR Vasconcelos, ... Anti-Cancer Drugs 28 (6), 634-644, 2017 | 21 | 2017 |
In vitro cytotoxicity, genotoxicity and antigenotoxicity assessment of Solanum lycocarpum hydroalcoholic extract AF Andrade, JM Alves, MB Corrêa, WR Cunha, RCS Veneziani, ... Pharmaceutical Biology 54 (11), 2786-2790, 2016 | 19 | 2016 |
The histone deacetylase inhibitor PCI-24781 as a putative radiosensitizer in pediatric glioblastoma cell lines PV de Andrade, AF Andrade, RG de Paula Queiroz, CA Scrideli, LG Tone, ... Cancer cell international 16, 1-11, 2016 | 16 | 2016 |
Chromosomal heterogeneity and instability characterize pediatric medulloblastoma cell lines and affect neoplastic phenotype AM Castro-Gamero, KS Borges, RC Lira, AF Andrade, PF Fedatto, ... Cytotechnology 65, 871-885, 2013 | 16 | 2013 |
A compendium of syngeneic, transplantable pediatric high-grade glioma models reveals subtype-specific therapeutic vulnerabilities M McNicholas, A De Cola, Z Bashardanesh, A Foss, CB Lloyd, S Hébert, ... Cancer discovery 13 (7), 1592-1615, 2023 | 12 | 2023 |
Molecular characterization of Wnt pathway and function of β-catenin overexpression in medulloblastoma cell lines L Geron, KB Salomão, KS Borges, AF Andrade, CAP Corrêa, CA Scrideli, ... Cytotechnology 70, 1713-1722, 2018 | 12 | 2018 |
Hypoxia-related gene expression profile in childhood acute lymphoblastic leukemia: prognostic implications VS Silveira, BMR Freire, KS Borges, AF Andrade, GAV Cruzeiro, ... Leukemia & Lymphoma 55 (8), 1751-1757, 2014 | 12 | 2014 |
Arsenic Trioxide exerts cytotoxic and radiosensitizing effects in pediatric Medulloblastoma cell lines of SHH Subgroup PH dos Santos Klinger, LEA Delsin, GAV Cruzeiro, AF Andrade, RCP Lira, ... Scientific Reports 10 (1), 6836, 2020 | 11 | 2020 |
Inhibition of SHH pathway mechanisms by arsenic trioxide in pediatric medulloblastomas: a comprehensive literature review PH Klinger, AF Andrade, LE Delsin, RG Queiroz, CA Scrideli, LG Tone, ... Genet Mol Res 16 (10.4238), 2017 | 10 | 2017 |
The carbonic anhydrase inhibitor E7070 sensitizes glioblastoma cells to radio-and chemotherapy and reduces tumor growth SA Teixeira, MS Viapiano, AF Andrade, MS Nandhu, JA Pezuk, ... Molecular Neurobiology 58 (9), 4520-4534, 2021 | 9 | 2021 |
Preventive activity of Copaifera langsdorffii Desf. leaves extract and its major compounds, afzelin and quercitrin, on DNA damage in in vitro and in vivo models SD Ozelin, JM Senedese, JM Alves, CC Munari, JDCD Costa, ... Journal of Toxicology and Environmental Health, Part A 84 (14), 569-581, 2021 | 8 | 2021 |
Antitumour activity of AMG 900 alone or in combination with histone deacetylase inhibitor SaHa on medulloblastoma cell lines L Geron, KS Borges, AF Andrade, VK Suazo, CA Scrideli, LG Tone Neurological Research 37 (8), 703-711, 2015 | 8 | 2015 |