High-level semi-synthetic production of the potent antimalarial artemisinin CJ Paddon, PJ Westfall, DJ Pitera, K Benjamin, K Fisher, D McPhee, ... Nature 496 (7446), 528-532, 2013 | 2273 | 2013 |
Bioethanol KA Gray, L Zhao, M Emptage Current opinion in chemical biology 10 (2), 141-146, 2006 | 1126 | 2006 |
Rewriting yeast central carbon metabolism for industrial isoprenoid production AL Meadows, KM Hawkins Nature 537, 694-697, 2016 | 603 | 2016 |
A gene cluster for macrolide antibiotic biosynthesis in Streptomyces venezuelae: architecture of metabolic diversity Y Xue, L Zhao, H Liu, DH Sherman Proceedings of the National Academy of Sciences 95 (21), 12111-12116, 1998 | 502 | 1998 |
Methylerythritol phosphate pathway of isoprenoid biosynthesis L Zhao, W Chang, Y Xiao, H Liu, P Liu Annual review of biochemistry 82, 497-530, 2013 | 343 | 2013 |
Recent applications of biocatalysis in developing green chemistry for chemical synthesis at the industrial scale N Ran, L Zhao, Z Chen, J Tao Green Chemistry 10 (4), 361-372, 2008 | 308 | 2008 |
Hydroxylation of macrolactones YC-17 and narbomycin is mediated by the pikC-encoded cytochrome P450 in Streptomyces venezuelae Y Xue, D Wilson, L Zhao, H Liu, DH Sherman Chemistry & biology 5 (11), 661-667, 1998 | 171 | 1998 |
Biosynthesis of desosamine: construction of a new macrolide carrying a genetically designed sugar moiety SA Borisova, L Zhao, DH Sherman, H Liu Organic letters 1 (1), 133-136, 1999 | 132 | 1999 |
Characterization of the glycosyltransferase activity of desVII: analysis of and implications for the biosynthesis of macrolide antibiotics SA Borisova, L Zhao, CE Melançon, CL Kao, H Liu Journal of the American Chemical Society 126 (21), 6534-6535, 2004 | 122 | 2004 |
Engineering a methymycin/pikromycin-calicheamicin hybrid: construction of two new macrolides carrying a designed sugar moiety L Zhao, J Ahlert, Y Xue, JS Thorson, DH Sherman, H Liu Journal of the American Chemical Society 121 (42), 9881-9882, 1999 | 118 | 1999 |
Recent advances in developing chemoenzymatic processes for active pharmaceutical ingredients J Tao, L Zhao, N Ran Organic process research & development 11 (2), 259-267, 2007 | 108 | 2007 |
Epoxide Hydrolase-Catalyzed Enantioselective Synthesis of Chiral 1, 2-Diols via Desymmetrization of m eso-Epoxides L Zhao, B Han, Z Huang, M Miller, H Huang, DS Malashock, Z Zhu, ... Journal of the American Chemical Society 126 (36), 11156-11157, 2004 | 108 | 2004 |
Biosynthesis of desosamine: construction of a new methymycin/neomethymycin analogue by deletion of a desosamine biosynthetic gene L Zhao, DH Sherman, H Liu Journal of the American Chemical Society 120 (39), 10256-10257, 1998 | 91 | 1998 |
Study of C-4 deoxygenation in the biosynthesis of desosamine: evidence implicating a novel mechanism L Zhao, S Borisova, SM Yeung, H Liu Journal of the American Chemical Society 123 (32), 7909-7910, 2001 | 73 | 2001 |
Mechanistic studies of desosamine biosynthesis: C-4 deoxygenation precedes C-3 transamination L Zhao, NLS Que, Y Xue, DH Sherman, H Liu Journal of the American Chemical Society 120 (46), 12159-12160, 1998 | 69 | 1998 |
Biosynthesis of TDP‐D‐Desosamine: Identification of a Strategy for C4 Deoxygenation P Szu, X He, L Zhao, H Liu Angewandte Chemie International Edition 44 (41), 6742-6746, 2005 | 67 | 2005 |
Expression, purification, and characterization of two N, N-dimethyltransferases, tylM1 and desVI, involved in the biosynthesis of mycaminose and desosamine H Chen, H Yamase, K Murakami, C Chang, L Zhao, Z Zhao, H Liu Biochemistry 41 (29), 9165-9183, 2002 | 61 | 2002 |
Monatin tabletop sweetener compositions and methods of making same T Abraham, D Cameron, M Goulson, P Hicks, M Lindley, S McFarlan, ... US Patent App. 10/903,582, 2004 | 59 | 2004 |
β-Glucosylation as a part of self-resistance mechanism in methymycin/pikromycin producing strain Streptomyces venezuelae L Zhao, NJ Beyer, SA Borisova, H Liu Biochemistry 42 (50), 14794-14804, 2003 | 57 | 2003 |
Engineering a functional 1-deoxy-D-xylulose 5-phosphate (DXP) pathway in Saccharomyces cerevisiae J Kirby, KL Dietzel, G Wichmann, R Chan, E Antipov, N Moss, EEK Baidoo, ... Metabolic Engineering 38, 494-503, 2016 | 54 | 2016 |