| Pain in endometriosis J Maddern, L Grundy, J Castro, SM Brierley Frontiers in cellular neuroscience 14, 590823, 2020 | 177 | 2020 |
| α-Conotoxin Vc1. 1 inhibits human dorsal root ganglion neuroexcitability and mouse colonic nociception via GABAB receptors J Castro, AM Harrington, S Garcia-Caraballo, J Maddern, L Grundy, ... Gut 66 (6), 1083-1094, 2017 | 93 | 2017 |
| Multiple sodium channel isoforms mediate the pathological effects of Pacific ciguatoxin-1 MC Inserra, MR Israel, A Caldwell, J Castro, JR Deuis, AM Harrington, ... Scientific reports 7 (1), 42810, 2017 | 82 | 2017 |
| Activation of pruritogenic TGR5, MrgprA3, and MrgprC11 on colon-innervating afferents induces visceral hypersensitivity J Castro, AM Harrington, TM Lieu, S Garcia-Caraballo, J Maddern, ... JCI insight 4 (20), 2019 | 68 | 2019 |
| Chronic linaclotide treatment reduces colitis-induced neuroplasticity and reverses persistent bladder dysfunction L Grundy, AM Harrington, J Castro, S Garcia-Caraballo, A Deiteren, ... JCI insight 3 (19), 2018 | 65 | 2018 |
| Gut enterochromaffin cells drive visceral pain and anxiety JR Bayrer, J Castro, A Venkataraman, KK Touhara, ND Rossen, ... Nature 616 (7955), 137-142, 2023 | 47 | 2023 |
| Cyclic analogues of α‐conotoxin Vc1. 1 inhibit colonic nociceptors and provide analgesia in a mouse model of chronic abdominal pain J Castro, L Grundy, A Deiteren, AM Harrington, T O'Donnell, J Maddern, ... British journal of pharmacology 175 (12), 2384-2398, 2018 | 39 | 2018 |
| Colonic afferent input and dorsal horn neuron activation differs between the thoracolumbar and lumbosacral spinal cord AM Harrington, SG Caraballo, JE Maddern, L Grundy, J Castro, ... American Journal of Physiology-Gastrointestinal and Liver Physiology 317 (3 …, 2019 | 36 | 2019 |
| Olorinab (APD371), a peripherally acting, highly selective, full agonist of the cannabinoid receptor 2, reduces colitis-induced acute and chronic visceral hypersensitivity in … J Castro, S Garcia-Caraballo, J Maddern, G Schober, A Lumsden, ... Pain 163 (1), e72-e86, 2022 | 21 | 2022 |
| Pharmacological Inhibition of the Voltage-Gated Sodium Channel NaV1.7 Alleviates Chronic Visceral Pain in a Rodent Model of Irritable Bowel Syndrome Y Jiang, J Castro, LV Blomster, AJ Agwa, J Maddern, G Schober, V Herzig, ... ACS pharmacology & translational science 4 (4), 1362-1378, 2021 | 16 | 2021 |
| A mouse model of endometriosis that displays vaginal, colon, cutaneous, and bladder sensory comorbidities J Castro, J Maddern, L Grundy, J Manavis, AM Harrington, G Schober, ... The FASEB Journal 35 (4), e21430, 2021 | 12 | 2021 |
| Pharmacological modulation of voltage-gated sodium (NaV) channels alters nociception arising from the female reproductive tract J Castro, J Maddern, A Erickson, A Caldwell, L Grundy, AM Harrington, ... Pain 162 (1), 227-242, 2021 | 9 | 2021 |
| A syngeneic inoculation mouse model of endometriosis that develops multiple comorbid visceral and cutaneous pain like behaviours J Maddern, L Grundy, A Harrington, G Schober, J Castro, SM Brierley Pain 163 (8), 1622-1635, 2022 | 6 | 2022 |
| Sa1738–Olorinab (Formerly Apd371), a peripherally restricted, highly selective, full agonist of the cannabinoid receptor 2 (CB2), reduces visceral hypersensitivity in animal models J Castro, J Maddern, S Garcia-Caraballo, AL Lumsden, B Lindstrom, ... Gastroenterology 156 (6), S-382, 2019 | 4 | 2019 |
| 561 chronic oral administration of the guanylate cyclase-C agonist linaclotide attenuates colitis induced bladder afferent hyperactivity LA Grundy, S Garcia-Carraballo, J Maddern, G Rychkov, G Hannig, ... Gastroenterology 150 (4), S118-S119, 2016 | 3 | 2016 |
| Peripheral and central neuroplasticity in a mouse model of endometriosis J Castro, J Maddern, A Erickson, AM Harrington, SM Brierley Journal of Neurochemistry, 2023 | 2 | 2023 |
| The voltage‐gated sodium channel NaV1.7 underlies endometriosis‐associated chronic pelvic pain J Castro, J Maddern, CY Chow, P Tran, I Vetter, GF King, SM Brierley Journal of Neurochemistry, 2023 | 2 | 2023 |
| Sa1078 cannabinoid receptor expression and the effect of Olorinab, a peripherally acting, highly selective, full agonist of the cannabinoid receptor 2 (CB2), in rodents with … J Castro, J Maddern, S Garcia-Caraballo, G Schober, B Lindstrom, ... Gastroenterology 158 (6), S-269, 2020 | 2 | 2020 |
| Su1578–chronic intracolonic administration of linaclotide inhibits nociceptive signaling in a mouse model of chronic visceral hypersensitivity J Castro, A Harrington, J Maddern, G Schober, LA Grundy, P Ge, ... Gastroenterology 156 (6), S-570, 2019 | 2 | 2019 |
| Chronic colonic administration of the guanylate cyclase-C agonist Lnaclotide attenuates colitis induced bladder afferent hyperactivity (Sal1677) L Grundy, J Castro, J Maddern, A Harrington, G Hannig, P Ge, S Brierley Gastroenterology 156 (6), S-363, 2019 | 1 | 2019 |
