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Jiaren Zhang
Jiaren Zhang
在 illinois.edu 的电子邮件经过验证
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Identifying mutation hotspots reveals pathogenetic mechanisms of KCNQ2 epileptic encephalopathy
J Zhang, EC Kim, C Chen, E Procko, S Pant, K Lam, J Patel, R Choi, ...
Scientific reports 10 (1), 1-19, 2020
542020
The role of Kv7 channels in neural plasticity and behavior
BC Baculis, J Zhang, HJ Chung
Frontiers in Physiology, 1206, 2020
382020
Reduced axonal surface expression and phosphoinositide sensitivity in Kv7 channels disrupts their function to inhibit neuronal excitability in Kcnq2 epileptic encephalopathy
EC Kim, J Zhang, W Pang, S Wang, KY Lee, JP Cavaretta, J Walters, ...
Neurobiology of disease 118, 76-93, 2018
352018
Heterozygous loss of epilepsy gene KCNQ2 alters social, repetitive and exploratory behaviors
EC Kim, J Patel, J Zhang, H Soh, JS Rhodes, AV Tzingounis, HJ Chung
Genes, Brain and Behavior 19 (1), e12599, 2020
342020
Spontaneous seizure and memory loss in mice expressing an epileptic encephalopathy variant in the calmodulin-binding domain of Kv7. 2
EC Kim, J Zhang, AY Tang, EC Bolton, JS Rhodes, CA Christian-Hinman, ...
Proceedings of the National Academy of Sciences 118 (51), 2021
162021
PIP2-dependent coupling of voltage sensor and pore domains in Kv7. 2 channel
S Pant, J Zhang, EC Kim, K Lam, HJ Chung, E Tajkhorshid
Communications biology 4 (1), 1-14, 2021
122021
An epilepsy-causing mutation leads to co-translational misfolding of the Kv7. 2 channel
J Urrutia, A Aguado, C Gomis-Perez, A Muguruza-Montero, ...
BMC biology 19 (1), 1-18, 2021
92021
Pharmacological inhibition of STriatal‐Enriched protein tyrosine Phosphatase by TC‐2153 reduces hippocampal excitability and seizure propensity
JM Walters, EC Kim, J Zhang, HG Jeong, A Bajaj, BC Baculis, GC Tracy, ...
Epilepsia, 2022
72022
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