| 5α, 8α-Epidioxysterols from the gorgonian Eunicella cavolini and the ascidian Trididemnum inarmatum: Isolation and evaluation of their antiproliferative activity E Ioannou, AF Abdel-Razik, M Zervou, D Christofidis, X Alexi, C Vagias, ... Steroids 74 (1), 73-80, 2009 | 118 | 2009 |
| Hallmarks of aromatase inhibitor drug resistance revealed by epigenetic profiling in breast cancer MPHM Jansen, T Knijnenburg, EA Reijm, I Simon, R Kerkhoven, M Droog, ... Cancer research 73 (22), 6632-6641, 2013 | 101 | 2013 |
| Estrogenic activity of isoflavonoids from Onobrychis ebenoides M Halabalaki, X Alexi, N Aligiannis, G Lambrinidis, H Pratsinis, I Florentin, ... Planta medica 72 (06), 488-493, 2006 | 71 | 2006 |
| Novel dehydroepiandrosterone derivatives with antiapoptotic, neuroprotective activity T Calogeropoulou, N Avlonitis, V Minas, X Alexi, A Pantzou, ... Journal of medicinal chemistry 52 (21), 6569-6587, 2009 | 66 | 2009 |
| Design and synthesis of novel neuroprotective 1, 2-dithiolane/chroman hybrids M Koufaki, C Kiziridi, X Alexi, MN Alexis Bioorganic & medicinal chemistry 17 (17), 6432-6441, 2009 | 56 | 2009 |
| The transcriptional co-factor RIP140 regulates mammary gland development by promoting the generation of key mitogenic signals J Nautiyal, JH Steel, MR Mane, O Oduwole, A Poliandri, X Alexi, N Wood, ... Development 140 (5), 1079-1089, 2013 | 54 | 2013 |
| Isoflavonoids from Erythrina poeppigiana: Evaluation of Their Binding Affinity for the Estrogen Receptor S Djiogue, M Halabalaki, X Alexi, D Njamen, ZT Fomum, MN Alexis, ... Journal of natural products 72 (9), 1603-1607, 2009 | 49 | 2009 |
| Co-regulated gene expression by oestrogen receptor α and liver receptor homolog-1 is a feature of the oestrogen response in breast cancer cells CF Lai, KD Flach, X Alexi, SP Fox, S Ottaviani, PTR Thiruchelvam, FJ Kyle, ... Nucleic acids research 41 (22), 10228-10240, 2013 | 47 | 2013 |
| PKA phosphorylation redirects ERα to promoters of a unique gene set to induce tamoxifen resistance R De Leeuw, K Flach, C Bentin Toaldo, X Alexi, S Canisius, J Neefjes, ... Oncogene 32 (30), 3543-3551, 2013 | 47 | 2013 |
| Synthesis of tropolone derivatives and evaluation of their in vitro neuroprotective activity M Koufaki, E Theodorou, X Alexi, F Nikoloudaki, MN Alexis European journal of medicinal chemistry 45 (3), 1107-1112, 2010 | 45 | 2010 |
| The effect of cell–ECM adhesion on signalling via the ErbB family of growth factor receptors X Alexi, F Berditchevski, E Odintsova Biochemical Society Transactions 39 (2), 568-573, 2011 | 43 | 2011 |
| Cytotoxic effects of 2-arylbenzofuran phytoestrogens on human cancer cells: modulation by adrenal and gonadal steroids ES Katsanou, M Halabalaki, N Aligiannis, S Mitakou, AL Skaltsounis, ... The Journal of steroid biochemistry and molecular biology 104 (3-5), 228-236, 2007 | 41 | 2007 |
| Isoxazole substituted chromans against oxidative stress-induced neuronal damage M Koufaki, A Tsatsaroni, X Alexi, H Guerrand, S Zerva, MN Alexis Bioorganic & medicinal chemistry 19 (16), 4841-4850, 2011 | 40 | 2011 |
| Biological and computational evaluation of resveratrol inhibitors against Alzheimer’s disease C Koukoulitsa, C Villalonga-Barber, R Csonka, X Alexi, G Leonis, D Dellis, ... Journal of enzyme inhibition and medicinal chemistry 31 (1), 67-77, 2016 | 38 | 2016 |
| Ebenfurans IV−VIII from Onobrychis ebenoides: Evidence that C-Prenylation is the Key Determinant of the Cytotoxicity of 3-Formyl-2-arylbenzofurans M Halabalaki, X Alexi, N Aligiannis, MN Alexis, AL Skaltsounis Journal of natural products 71 (11), 1934-1937, 2008 | 38 | 2008 |
| Comparison of thermal effects of stilbenoid analogs in lipid bilayers using differential scanning calorimetry and molecular dynamics: correlation of thermal effects and … C Koukoulitsa, S Durdagi, E Siapi, C Villalonga-Barber, X Alexi, ... European Biophysics Journal 40, 865-875, 2011 | 32 | 2011 |
| 9, 11-Secosterols with antiproliferative activity from the gorgonian Eunicella cavolini E Ioannou, AF Abdel-Razik, X Alexi, C Vagias, MN Alexis, V Roussis Bioorganic & medicinal chemistry 17 (13), 4537-4541, 2009 | 32 | 2009 |
| Ester and carbamate ester derivatives of Biochanin A: Synthesis and in vitro evaluation of estrogenic and antiproliferative activities N Fokialakis, X Alexi, N Aligiannis, D Siriani, AK Meligova, H Pratsinis, ... Bioorganic & medicinal chemistry 20 (9), 2962-2970, 2012 | 30 | 2012 |
| Protein Kinase A-induced tamoxifen resistance is mediated by anchoring protein AKAP13 C Bentin Toaldo, X Alexi, K Beelen, M Kok, M Hauptmann, M Jansen, ... BMC cancer 15, 1-12, 2015 | 28 | 2015 |
| IGF‐1R pathway activation as putative biomarker for linsitinib therapy to revert tamoxifen resistance in ER‐positive breast cancer DT Kruger, X Alexi, M Opdam, K Schuurman, L Voorwerk, J Sanders, ... International journal of cancer 146 (8), 2348-2359, 2020 | 27 | 2020 |
