Oligomycin frames a common drug-binding site in the ATP synthase J Symersky, D Osowski, DE Walters, DM Mueller Proceedings of the National Academy of Sciences 109 (35), 13961-13965, 2012 | 273 | 2012 |
Potent HIV protease inhibitors incorporating high-affinity P2-ligands and (R)-(hydroxyethylamino) sulfonamide isostere AK Ghosh, JF Kincaid, W Cho, DE Walters, K Krishnan, KA Hussain, ... Bioorganic & medicinal chemistry letters 8 (6), 687-690, 1998 | 227 | 1998 |
Commercial, synthetic nonnutritive sweeteners DJ Ager, DP Pantaleone, SA Henderson, AR Katritzky, I Prakash, ... Angewandte Chemie International Edition 37 (13‐14), 1802-1817, 1998 | 176 | 1998 |
Structure-based design of novel HIV-1 protease inhibitors to combat drug resistance AK Ghosh, PR Sridhar, S Leshchenko, AK Hussain, J Li, AY Kovalevsky, ... Journal of medicinal chemistry 49 (17), 5252-5261, 2006 | 173 | 2006 |
Molecular dynamics study of a polymeric reverse osmosis membrane E Harder, DE Walters, YD Bodnar, RS Faibish, B Roux The Journal of Physical Chemistry B 113 (30), 10177-10182, 2009 | 166 | 2009 |
Microbial transformations of antitumor compounds. 1. Conversion of acronycine to 9-hydroxyacronycine by Cunninghamella echinulata RE Betts, DE Walters, JP Rosazza Journal of medicinal chemistry 17 (6), 599-602, 1974 | 155 | 1974 |
Concentration—response relationships of sweeteners: a systematic study GE DuBois, DE Walters, SS Schiffman, ZS Warwick, BJ Booth, SD Pecore, ... | 131 | 1991 |
Nonpeptidal P2 ligands for HIV protease inhibitors: structure-based design, synthesis, and biological evaluation AK Ghosh, JF Kincaid, DE Walters, Y Chen, NC Chaudhuri, ... Journal of medicinal chemistry 39 (17), 3278-3290, 1996 | 130 | 1996 |
Genetically evolved receptor models: a computational approach to construction of receptor models DE Walters, RM Hinds Journal of Medicinal Chemistry 37 (16), 2527-2536, 1994 | 129 | 1994 |
Design and synthesis of novel HIV-1 protease inhibitors incorporating oxyindoles as the P2′-ligands AK Ghosh, G Schiltz, RS Perali, S Leshchenko, S Kay, DE Walters, Y Koh, ... Bioorganic & medicinal chemistry letters 16 (7), 1869-1873, 2006 | 113 | 2006 |
Conformational changes in BAK, a pore-forming proapoptotic Bcl-2 family member, upon membrane insertion and direct evidence for the existence of BH3-BH3 contact interface in … KJ Oh, P Singh, K Lee, K Foss, S Lee, M Park, S Lee, S Aluvila, M Park, ... Journal of biological chemistry 285 (37), 28924-28937, 2010 | 103 | 2010 |
Sweeteners: discovery, molecular design, and chemoreception DE Walters, FT Orthoefer, GE DuBois American Chemical Society, 1991 | 95 | 1991 |
Probing the “dark” fraction of core–shell quantum dots by ensemble and single particle pH-dependent spectroscopy N Durisic, AG Godin, D Walters, P Grütter, PW Wiseman, CD Heyes ACS nano 5 (11), 9062-9073, 2011 | 88 | 2011 |
Design and Synthesis of Potent HIV-1 Protease Inhibitors Incorporating Hexahydrofuropyranol-Derived High Affinity P2 Ligands: Structure−Activity Studies and … AK Ghosh, BD Chapsal, A Baldridge, MP Steffey, DE Walters, Y Koh, ... Journal of medicinal chemistry 54 (2), 622-634, 2011 | 82 | 2011 |
Mitochondrial and plasma membrane citrate transporters: discovery of selective inhibitors and application to structure/function analysis J Sun, S Aluvila, R Kotaria, JA Mayor, DE Walters, RS Kaplan Molecular and cellular pharmacology 2 (3), 101, 2010 | 77 | 2010 |
The yeast mitochondrial citrate transport protein: probing the secondary structure of transmembrane domain IV and identification of residues that likely comprise a portion of … RS Kaplan, JA Mayor, D Brauer, R Kotaria, DE Walters, AM Dean Journal of biological chemistry 275 (16), 12009-12016, 2000 | 77 | 2000 |
How are bitter and sweet tastes related? DE Walters Trends in Food Science & Technology 7 (12), 399-403, 1996 | 74 | 1996 |
The yeast mitochondrial citrate transport protein: probing the roles of cysteines, Arg181, and Arg189 in transporter function Y Xu, DA Kakhniashvili, DA Gremse, DO Wood, JA Mayor, DE Walters, ... Journal of biological chemistry 275 (10), 7117-7124, 2000 | 71 | 2000 |
Structure-based design: synthesis and biological evaluation of a series of novel cycloamide-derived HIV-1 protease inhibitors AK Ghosh, LM Swanson, H Cho, S Leshchenko, KA Hussain, S Kay, ... Journal of medicinal chemistry 48 (10), 3576-3585, 2005 | 70 | 2005 |
Structure and dynamic behavior of the oligosaccharide side chain of bovine pancreatic ribonuclease B. Application of carbon 13 nuclear magnetic resonance spectroscopy. E Berman, DE Walters, A Allerhand Journal of Biological Chemistry 256 (8), 3853-3857, 1981 | 68 | 1981 |