Monophosphorylation of CD79a and CD79b ITAM motifs initiates a SHIP-1 phosphatase-mediated inhibitory signaling cascade required for B cell anergy SK O'Neill, A Getahun, SB Gauld, KT Merrell, I Tamir, MJ Smith, ... Immunity 35 (5), 746-756, 2011 | 206 | 2011 |
B cells in type 1 diabetes mellitus and diabetic kidney disease MJ Smith, KM Simmons, JC Cambier Nature Reviews Nephrology 13 (11), 712-720, 2017 | 128 | 2017 |
Tissue distribution and clonal diversity of the T and B cell repertoire in type 1 diabetes HR Seay, E Yusko, SJ Rothweiler, L Zhang, AL Posgai, ... JCI insight 1 (20), 2016 | 123 | 2016 |
Loss of anergic B cells in prediabetic and new-onset type 1 diabetic patients MJ Smith, TA Packard, SK O’Neill, CJ Henry Dunand, M Huang, ... Diabetes 64 (5), 1703-1712, 2015 | 97 | 2015 |
B cells and type 1 diabetes… in mice and men RM Hinman, MJ Smith, JC Cambier Immunology letters 160 (2), 128-132, 2014 | 63 | 2014 |
Mesenchymal stem cells recruit CCR2+ monocytes to suppress allergic airway inflammation K Takeda, TL Webb, F Ning, Y Shiraishi, DP Regan, L Chow, MJ Smith, ... The Journal of Immunology 200 (4), 1261-1269, 2018 | 59 | 2018 |
Anti-CD79 antibody induces B cell anergy that protects against autoimmunity IR Hardy, N Anceriz, F Rousseau, MB Seefeldt, E Hatterer, M Irla, ... The Journal of Immunology 192 (4), 1641-1650, 2014 | 49 | 2014 |
Elevated PTEN expression maintains anergy in human B cells and reveals unexpectedly high repertoire autoreactivity MJ Smith, BR Ford, M Rihanek, BM Coleman, A Getahun, VD Sarapura, ... JCI insight 4 (3), 2019 | 48 | 2019 |
Activation of thyroid antigen-reactive B cells in recent onset autoimmune thyroid disease patients MJ Smith, M Rihanek, BM Coleman, PA Gottlieb, VD Sarapura, ... Journal of autoimmunity 89, 82-89, 2018 | 46 | 2018 |
Detection and enrichment of rare antigen-specific B cells for analysis of phenotype and function MJ Smith, TA Packard, SK O'Neill, RM Hinman, M Rihanek, PA Gottlieb, ... JoVE (Journal of Visualized Experiments), e55382, 2017 | 45 | 2017 |
Loss of B-cell anergy in type 1 diabetes is associated with high-risk HLA and non-HLA disease susceptibility alleles MJ Smith, M Rihanek, C Wasserfall, CE Mathews, MA Atkinson, ... Diabetes 67 (4), 697-703, 2018 | 30 | 2018 |
Silencing of high-affinity insulin-reactive B lymphocytes by anergy and impact of the NOD genetic background in mice MJ Smith, RM Hinman, A Getahun, S Kim, TA Packard, JC Cambier Diabetologia 61, 2621-2632, 2018 | 23 | 2018 |
Endotypes in T1D: B lymphocytes and early onset MJ Smith, JC Cambier, PA Gottlieb Current Opinion in Endocrinology, Diabetes and Obesity 27 (4), 225-230, 2020 | 22 | 2020 |
B cell receptor affinity for insulin dictates autoantigen acquisition and B cell functionality in autoimmune diabetes TA Packard, MJ Smith, FJ Conrad, SA Johnson, A Getahun, RS Lindsay, ... Journal of Clinical Medicine 5 (11), 98, 2016 | 19 | 2016 |
Autoantibodies elicited with SARS-CoV-2 infection are linked to alterations in double negative B cells MJ Castleman, MM Stumpf, NR Therrien, MJ Smith, KE Lesteberg, ... Frontiers in immunology 13, 988125, 2022 | 16 | 2022 |
SARS-CoV-2 infection relaxes peripheral B cell tolerance MJ Castleman, MM Stumpf, NR Therrien, MJ Smith, KE Lesteberg, ... Journal of Experimental Medicine 219 (6), e20212553, 2022 | 16 | 2022 |
Retention of anergy and inhibition of antibody responses during acute gammaherpesvirus 68 infection A Getahun, MJ Smith, I Kogut, LF van Dyk, JC Cambier The Journal of Immunology 189 (6), 2965-2974, 2012 | 15 | 2012 |
Therapeutic targeting of autoreactive B cells: why, how, and when? ZC Stensland, JC Cambier, MJ Smith Biomedicines 9 (1), 83, 2021 | 13 | 2021 |
Charge delocalization upon chloride ion binding in ClC chloride ion channels/transporters M Smith, H Lin Chemical Physics Letters 502 (1-3), 112-117, 2011 | 12 | 2011 |
Identification of an anergic BND cell–derived activated B cell population (BND2) in young-onset type 1 diabetes patients ZC Stensland, CA Magera, H Broncucia, BD Gomez, NM Rios-Guzman, ... Journal of Experimental Medicine 220 (8), e20221604, 2023 | 8 | 2023 |