Phosphodiesterase 9A controls nitric-oxide-independent cGMP and hypertrophic heart disease DI Lee, G Zhu, T Sasaki, GS Cho, N Hamdani, R Holewinski, SH Jo, ... Nature 519 (7544), 472-476, 2015 | 349 | 2015 |
Autophagy and p62 in cardiac proteinopathy Q Zheng, H Su, MJ Ranek, X Wang Circulation research 109 (3), 296-308, 2011 | 201 | 2011 |
Protein quality control and degradation in cardiomyocytes X Wang, H Su, MJ Ranek Journal of molecular and cellular cardiology 45 (1), 11-27, 2008 | 133 | 2008 |
Mast cells regulate myofilament calcium sensitization and heart function after myocardial infarction A Ngkelo, A Richart, JA Kirk, P Bonnin, J Vilar, M Lemitre, P Marck, ... Journal of Experimental Medicine 213 (7), 1353-1374, 2016 | 121 | 2016 |
Protein kinase g positively regulates proteasome-mediated degradation of misfolded proteins MJ Ranek, EJM Terpstra, J Li, DA Kass, X Wang Circulation 128 (4), 365-376, 2013 | 121 | 2013 |
COP9 signalosome regulates autophagosome maturation H Su, F Li, MJ Ranek, N Wei, X Wang Circulation 124 (19), 2117-2128, 2011 | 121 | 2011 |
In vivo selective inhibition of TRPC6 by antagonist BI 749327 ameliorates fibrosis and dysfunction in cardiac and renal disease BL Lin, D Matera, JF Doerner, N Zheng, D Del Camino, S Mishra, H Bian, ... Proceedings of the National Academy of Sciences 116 (20), 10156-10161, 2019 | 120 | 2019 |
The role of heat shock proteins and co-chaperones in heart failure MJ Ranek, MJ Stachowski, JA Kirk, MS Willis Philosophical Transactions of the Royal Society B: Biological Sciences 373 …, 2018 | 120 | 2018 |
PKG1-modified TSC2 regulates mTORC1 activity to counter adverse cardiac stress MJ Ranek, KM Kokkonen-Simon, A Chen, BL Dunkerly-Eyring, MP Vera, ... Nature 566 (7743), 264-269, 2019 | 111 | 2019 |
Histone lysine dimethyl-demethylase KDM3A controls pathological cardiac hypertrophy and fibrosis QJ Zhang, TAT Tran, M Wang, MJ Ranek, KM Kokkonen-Simon, J Gao, ... Nature communications 9 (1), 5230, 2018 | 96 | 2018 |
Prevention of PKG1α oxidation augments cardioprotection in the stressed heart T Nakamura, MJ Ranek, DI Lee, VS Hahn, C Kim, P Eaton, DA Kass The Journal of clinical investigation 125 (6), 2468-2472, 2015 | 78 | 2015 |
Activation of the ubiquitin-proteasome system in doxorubicin cardiomyopathy MJ Ranek, X Wang Current hypertension reports 11 (6), 389-395, 2009 | 72 | 2009 |
The pathophysiology of cardiac hypertrophy and heart failure WE Stansfield, M Ranek, A Pendse, JC Schisler, S Wang, T Pulinilkunnil, ... Cellular and molecular pathobiology of cardiovascular disease, 51-78, 2014 | 50 | 2014 |
Functional amyloid signaling via the inflammasome, necrosome, and signalosome: new therapeutic targets in heart failure TL Parry, JH Melehani, MJ Ranek, MS Willis Frontiers in Cardiovascular Medicine 2, 25, 2015 | 49 | 2015 |
Protein S-Nitrosylation Controls Glycogen Synthase Kinase 3β Function Independent of Its Phosphorylation State SB Wang, V Venkatraman, EL Crowgey, T Liu, Z Fu, R Holewinski, ... Circulation research 122 (11), 1517-1531, 2018 | 45 | 2018 |
Soluble guanylate cyclase is required for systemic vasodilation but not positive inotropy induced by nitroxyl in the mouse G Zhu, D Groneberg, G Sikka, D Hori, MJ Ranek, T Nakamura, E Takimoto, ... Hypertension 65 (2), 385-392, 2015 | 43 | 2015 |
Genetically induced moderate inhibition of 20S proteasomes in cardiomyocytes facilitates heart failure in mice during systolic overload MJ Ranek, H Zheng, W Huang, AR Kumarapeli, J Li, J Liu, X Wang Journal of molecular and cellular cardiology 85, 273-281, 2015 | 39 | 2015 |
MTORC1-regulated metabolism controlled by TSC2 limits cardiac reperfusion injury CU Oeing, S Jun, S Mishra, BL Dunkerly-Eyring, A Chen, MI Grajeda, ... Circulation research 128 (5), 639-651, 2021 | 35 | 2021 |
CHIP phosphorylation by protein kinase G enhances protein quality control and attenuates cardiac ischemic injury MJ Ranek, C Oeing, R Sanchez-Hodge, KM Kokkonen-Simon, D Dillard, ... Nature communications 11 (1), 5237, 2020 | 32 | 2020 |
PKG1α cysteine-42 redox state controls mTORC1 activation in pathological cardiac hypertrophy CU Oeing, T Nakamura, S Pan, S Mishra, BL Dunkerly-Eyring, ... Circulation research 127 (4), 522-533, 2020 | 32 | 2020 |