Cu (II) potentiation of Alzheimer Aβ neurotoxicity: correlation with cell-free hydrogen peroxide production and metal reduction X Huang, MP Cuajungco, CS Atwood, MA Hartshorn, JDA Tyndall, ... Journal of Biological Chemistry 274 (52), 37111-37116, 1999 | 1008 | 1999 |
The toxicogenomic multiverse: convergent recruitment of proteins into animal venoms BG Fry, K Roelants, DE Champagne, H Scheib, JDA Tyndall, GF King, ... Annual review of genomics and human genetics 10 (1), 483-511, 2009 | 870 | 2009 |
Proteases universally recognize beta strands in their active sites JDA Tyndall, T Nall, DP Fairlie Chemical Reviews 105 (3), 973-1000, 2005 | 478 | 2005 |
Over one hundred peptide-activated G protein-coupled receptors recognize ligands with turn structure JDA Tyndall, B Pfeiffer, G Abbenante, DP Fairlie Chemical reviews 105 (3), 793-826, 2005 | 293 | 2005 |
Architecture of a single membrane spanning cytochrome P450 suggests constraints that orient the catalytic domain relative to a bilayer BC Monk, TM Tomasiak, MV Keniya, FU Huschmann, JDA Tyndall, ... Proceedings of the National Academy of Sciences 111 (10), 3865-3870, 2014 | 284 | 2014 |
Beta-strand mimetics WA Loughlin, JDA Tyndall, MP Glenn, DP Fairlie Chemical reviews 104 (12), 6085-6118, 2004 | 283 | 2004 |
Isolation and characterization of a cone snail protease with homology to CRISP proteins of the pathogenesis-related protein superfamily TJ Milne, G Abbenante, JDA Tyndall, J Halliday, RJ Lewis Journal of Biological Chemistry 278 (33), 31105-31110, 2003 | 275 | 2003 |
Conformational selection of inhibitors and substrates by proteolytic enzymes: implications for drug design and polypeptide processing DP Fairlie, JDA Tyndall, RC Reid, AK Wong, G Abbenante, MJ Scanlon, ... Journal of Medicinal Chemistry 43 (7), 1271-1281, 2000 | 216 | 2000 |
Update 1 of: Proteases universally recognize beta strands in their active sites PK Madala, JDA Tyndall, T Nall, DP Fairlie Chemical reviews 110 (6), PR1-PR31, 2011 | 209 | 2011 |
Proteases and protease inhibitors in infectious diseases AA Agbowuro, WM Huston, AB Gamble, JDA Tyndall Medicinal research reviews 38 (4), 1295-1331, 2018 | 182 | 2018 |
Structural insights into binding of the antifungal drug fluconazole to Saccharomyces cerevisiae lanosterol 14α-demethylase AA Sagatova, MV Keniya, RK Wilson, BC Monk, JDA Tyndall Antimicrobial agents and chemotherapy 59 (8), 4982-4989, 2015 | 178 | 2015 |
TCR-or cytokine-activated CD8+ mucosal-associated invariant T cells are rapid polyfunctional effectors that can coordinate immune responses R Lamichhane, M Schneider, SM de la Harpe, TWR Harrop, ... Cell reports 28 (12), 3061-3076. e5, 2019 | 167 | 2019 |
Crystal structure of a thermostable lipase from Bacillus stearothermophilus P1 JDA Tyndall, S Sinchaikul, LA Fothergill-Gilmore, P Taylor, ... Journal of Molecular Biology 323 (5), 859-869, 2002 | 161 | 2002 |
GPCR agonists and antagonists in the clinic JDA Tyndall, R Sandilya Medicinal chemistry 1 (4), 405-421, 2005 | 142 | 2005 |
Enzymatic characterization and homology model of a catalytically active recombinant West Nile virus NS3 protease TA Nall, KJ Chappell, MJ Stoermer, NX Fang, JDA Tyndall, PR Young, ... Journal of Biological Chemistry 279 (47), 48535-48542, 2004 | 140 | 2004 |
Potent cyclic antagonists of the complement C5a receptor on human polymorphonuclear leukocytes. Relationships between structures and activity DR March, LM Proctor, MJ Stoermer, R Sbaglia, G Abbenante, RC Reid, ... Molecular pharmacology 65 (4), 868-879, 2004 | 140 | 2004 |
Cannabinoid CB1 and CB2 receptor ligand specificity and the development of CB2-selective agonists JC Ashton, JL Wright, JM McPartland, JDA Tyndall Current medicinal chemistry 15 (14), 1428-1443, 2008 | 129 | 2008 |
Macrocycles mimic the extended peptide conformation recognized by aspartic, serine, cysteine and metallo proteases JDA Tyndall, DP Fairlie Current medicinal chemistry 8 (8), 893-907, 2001 | 125 | 2001 |
Abc1p Is a Multidrug Efflux Transporter That Tips the Balance in Favor of Innate Azole Resistance in Candida krusei E Lamping, A Ranchod, K Nakamura, JDA Tyndall, K Niimi, AR Holmes, ... Antimicrobial agents and chemotherapy 53 (2), 354-369, 2009 | 123 | 2009 |
Crystal structures of full-length lanosterol 14α-demethylases of prominent fungal pathogens Candida albicans and Candida glabrata provide tools for antifungal discovery MV Keniya, M Sabherwal, RK Wilson, MA Woods, AA Sagatova, ... Antimicrobial agents and chemotherapy 62 (11), 10.1128/aac. 01134-18, 2018 | 110 | 2018 |