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Tiago Donatelli Serafim
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Gut microbes egested during bites of infected sand flies augment severity of leishmaniasis via inflammasome-derived IL-1β
R Dey, AB Joshi, F Oliveira, L Pereira, AB Guimarães-Costa, TD Serafim, ...
Cell host & microbe 23 (1), 134-143. e6, 2018
1752018
Sequential blood meals promote Leishmania replication and reverse metacyclogenesis augmenting vector infectivity
TD Serafim, IV Coutinho-Abreu, F Oliveira, C Meneses, S Kamhawi, ...
Nature microbiology 3 (5), 548-555, 2018
1482018
The Gut Microbiome of the Vector Lutzomyia longipalpis Is Essential for Survival of Leishmania infantum
PH Kelly, SM Bahr, TD Serafim, NJ Ajami, JF Petrosino, C Meneses, ...
MBio 8 (1), 10.1128/mbio. 01121-16, 2017
1312017
A second generation leishmanization vaccine with a markerless attenuated Leishmania major strain using CRISPR gene editing
WW Zhang, S Karmakar, S Gannavaram, R Dey, P Lypaczewski, N Ismail, ...
Nature Communications 11 (1), 3461, 2020
982020
Leishmaniasis: the act of transmission
TD Serafim, IV Coutinho-Abreu, R Dey, R Kissinger, JG Valenzuela, ...
Trends in parasitology 37 (11), 976-987, 2021
732021
Leishmania Metacyclogenesis Is Promoted in the Absence of Purines
TD Serafim, AB Figueiredo, PAC Costa, EA Marques-da-Silva, ...
Public Library of Science 6 (9), e1833, 2012
662012
Leishmania amazonensis impairs DC function by inhibiting CD40 expression via A2B adenosine receptor activation
AB Figueiredo, TD Serafim, EA Marques‐da‐Silva, JR Meyer‐Fernandes, ...
European journal of immunology 42 (5), 1203-1215, 2012
552012
Protein‐energy malnutrition decreases immune response to Leishmania chagasi vaccine in BALB/c mice
G Malafaia, TD Serafim, ME Silva, ML Pedrosa, SA Rezende
Parasite immunology 31 (1), 41-49, 2009
552009
Genome-wide and protein kinase-focused RNAi screens reveal conserved and novel damage response pathways in Trypanosoma brucei
JA Stortz, TD Serafim, S Alsford, J Wilkes, F Fernandez-Cortes, ...
PLoS pathogens 13 (7), e1006477, 2017
512017
Immune response to Leishmania (Leishmania) chagasi infection is reduced in malnourished BALB/c mice
TD Serafim, G Malafaia, ME Silva, ML Pedrosa, SA Rezende
Memorias do Instituto Oswaldo Cruz 105, 811-817, 2010
492010
Ecto-Nucleotidase Activities of Promastigotes from Leishmania (Viannia) braziliensis Relates to Parasite Infectivity and Disease Clinical Outcome
PM Leite, RS Gomes, AB Figueiredo, TD Serafim, WL Tafuri, ...
Public Library of Science 6 (10), e1850, 2012
422012
Leishmania infantum
TD Serafim, E Iniguez, F Oliveira
Trends in parasitology 36 (1), 80-81, 2020
392020
RNAi screening identifies Trypanosoma brucei stress response protein kinases required for survival in the mouse
F Fernandez-Cortes, TD Serafim, JM Wilkes, NG Jones, R Ritchie, ...
Scientific reports 7 (1), 6156, 2017
312017
Leishmania infantum Ecto-Nucleoside Triphosphate Diphosphohydrolase-2 is an Apyrase Involved in Macrophage Infection and Expressed in Infected Dogs
RDS Vasconcellos, C Mariotini-Moura, RS Gomes, TD Serafim, ...
PLoS Neglected Tropical Diseases 8 (11), e3309, 2014
282014
A sand fly salivary protein acts as a neutrophil chemoattractant
AB Guimaraes-Costa, JP Shannon, I Waclawiak, J Oliveira, C Meneses, ...
Nature Communications 12 (1), 3213, 2021
242021
Distinct gene expression patterns in vector-residing Leishmania infantum identify parasite stage-enriched markers
IV Coutinho-Abreu, TD Serafim, C Meneses, S Kamhawi, F Oliveira, ...
PLoS Neglected Tropical Diseases 14 (3), e0008014, 2020
242020
Leishmania infection induces a limited differential gene expression in the sand fly midgut
IV Coutinho-Abreu, TD Serafim, C Meneses, S Kamhawi, F Oliveira, ...
BMC genomics 21, 1-16, 2020
212020
Engineering a vector-based pan-Leishmania vaccine for humans: proof of principle
P Cecílio, J Oristian, C Meneses, TD Serafim, JG Valenzuela, ...
Scientific Reports 10 (1), 18653, 2020
132020
Heme oxygenase-1 induction by blood-feeding arthropods controls skin inflammation and promotes disease tolerance
T DeSouza-Vieira, E Iniguez, TD Serafim, W de Castro, S Karmakar, ...
Cell Reports 33 (4), 2020
132020
Towards a sustainable vector-control strategy in the post kala-azar elimination era
R Garlapati, E Iniguez, TD Serafim, PK Mishra, B Rooj, B Sinha, ...
Frontiers in Cellular and Infection Microbiology 11, 641632, 2021
112021
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