Structural basis for translational shutdown and immune evasion by the Nsp1 protein of SARS-CoV-2 M Thoms, R Buschauer, M Ameismeier, L Koepke, T Denk, ... Science 369 (6508), 1249-1255, 2020 | 788 | 2020 |
Crystal structure of TET2-DNA complex: insight into TET-mediated 5mC oxidation L Hu, Z Li, J Cheng, Q Rao, W Gong, M Liu, YG Shi, J Zhu, P Wang, Y Xu Cell 155 (7), 1545-1555, 2013 | 461 | 2013 |
Structural insight into substrate preference for TET-mediated oxidation L Hu, J Lu, J Cheng, Q Rao, Z Li, H Hou, Z Lou, L Zhang, W Li, W Gong, ... Nature 527 (7576), 118-122, 2015 | 295 | 2015 |
Collided ribosomes form a unique structural interface to induce Hel2‐driven quality control pathways K Ikeuchi, P Tesina, Y Matsuo, T Sugiyama, J Cheng, Y Saeki, K Tanaka, ... The EMBO journal 38 (5), e100276, 2019 | 266 | 2019 |
Architecture of the 90S pre-ribosome: a structural view on the birth of the eukaryotic ribosome M Kornprobst, M Turk, N Kellner, J Cheng, D Flemming, I Koš-Braun, ... Cell 166 (2), 380-393, 2016 | 226 | 2016 |
The Ccr4-Not complex monitors the translating ribosome for codon optimality R Buschauer, Y Matsuo, T Sugiyama, YH Chen, N Alhusaini, T Sweet, ... Science 368 (6488), eaay6912, 2020 | 216 | 2020 |
Visualizing the assembly pathway of nucleolar pre-60S ribosomes L Kater, M Thoms, C Barrio-Garcia, J Cheng, S Ismail, YL Ahmed, ... Cell 171 (7), 1599-1610. e14, 2017 | 186 | 2017 |
The cryo-electron microscopy structure of huntingtin Q Guo, B Huang, J Cheng, M Seefelder, T Engler, G Pfeifer, P Oeckl, ... Nature 555 (7694), 117-120, 2018 | 181 | 2018 |
Molecular mechanism for USP7-mediated DNMT1 stabilization by acetylation J Cheng, H Yang, J Fang, L Ma, R Gong, P Wang, Z Li, Y Xu Nature communications 6 (1), 7023, 2015 | 141 | 2015 |
Molecular mechanism of translational stalling by inhibitory codon combinations and poly (A) tracts P Tesina, LN Lessen, R Buschauer, J Cheng, CCC Wu, O Berninghausen, ... The EMBO journal 39 (3), e103365, 2020 | 138 | 2020 |
Structural insight into coordinated recognition of trimethylated histone H3 lysine 9 (H3K9me3) by the plant homeodomain (PHD) and tandem tudor domain (TTD) of UHRF1 (ubiquitin … J Cheng, Y Yang, J Fang, J Xiao, T Zhu, F Chen, P Wang, Z Li, H Yang, ... Journal of Biological Chemistry 288 (2), 1329-1339, 2013 | 130 | 2013 |
Visualizing late states of human 40S ribosomal subunit maturation M Ameismeier, J Cheng, O Berninghausen, R Beckmann Nature 558 (7709), 249-253, 2018 | 129 | 2018 |
Hemi-methylated DNA opens a closed conformation of UHRF1 to facilitate its histone recognition J Fang, J Cheng, J Wang, Q Zhang, M Liu, R Gong, P Wang, X Zhang, ... Nature communications 7 (1), 11197, 2016 | 125 | 2016 |
3.2-Å-resolution structure of the 90S preribosome before A1 pre-rRNA cleavage J Cheng, N Kellner, O Berninghausen, E Hurt, R Beckmann Nature structural & molecular biology 24 (11), 954-964, 2017 | 110 | 2017 |
RQT complex dissociates ribosomes collided on endogenous RQC substrate SDD1 Y Matsuo, P Tesina, S Nakajima, M Mizuno, A Endo, R Buschauer, ... Nature structural & molecular biology 27 (4), 323-332, 2020 | 104 | 2020 |
Crystal structure of the Gtr1p–Gtr2p complex reveals new insights into the amino acid-induced TORC1 activation R Gong, L Li, Y Liu, P Wang, H Yang, L Wang, J Cheng, KL Guan, Y Xu Genes & development 25 (16), 1668-1673, 2011 | 103 | 2011 |
The force-sensing peptide VemP employs extreme compaction and secondary structure formation to induce ribosomal stalling T Su, J Cheng, D Sohmen, R Hedman, O Berninghausen, G von Heijne, ... elife 6, e25642, 2017 | 88 | 2017 |
Structure and function of Vms1 and Arb1 in RQC and mitochondrial proteome homeostasis T Su, T Izawa, M Thoms, Y Yamashita, J Cheng, O Berninghausen, ... Nature 570 (7762), 538-542, 2019 | 79 | 2019 |
Structure and function of yeast Lso2 and human CCDC124 bound to hibernating ribosomes JN Wells, R Buschauer, T Mackens-Kiani, K Best, H Kratzat, ... PLoS biology 18 (7), e3000780, 2020 | 76 | 2020 |
Structure of the 80S ribosome–Xrn1 nuclease complex P Tesina, E Heckel, J Cheng, M Fromont-Racine, R Buschauer, L Kater, ... Nature Structural & Molecular Biology 26 (4), 275-280, 2019 | 75 | 2019 |