The phosphorylation state of eucaryotic initiation factor 2 alters translational efficiency of specific mRNAs RJ Kaufman, MV Davies, VK Pathak, JWB Hershey Molecular and cellular biology, 1989 | 515 | 1989 |
Broad spectrum of in vivo forward mutations, hypermutations, and mutational hotspots in a retroviral shuttle vector after a single replication cycle: substitutions, frameshifts … VK Pathak, HM Temin Proceedings of the National Academy of Sciences 87 (16), 6019-6023, 1990 | 511 | 1990 |
Human immunodeficiency virus type 1 cDNAs produced in the presence of APOBEC3G exhibit defects in plus-strand DNA transfer and integration JL Mbisa, R Barr, JA Thomas, N Vandegraaff, IJ Dorweiler, ... Journal of virology 81 (13), 7099-7110, 2007 | 339 | 2007 |
Human apolipoprotein B mRNA-editing enzyme-catalytic polypeptide-like 3G (APOBEC3G) is incorporated into HIV-1 virions through interactions with viral and nonviral RNAs ES Svarovskaia, H Xu, JL Mbisa, R Barr, RJ Gorelick, A Ono, EO Freed, ... Journal of Biological Chemistry 279 (34), 35822-35828, 2004 | 300 | 2004 |
A single amino acid substitution in human APOBEC3G antiretroviral enzyme confers resistance to HIV-1 virion infectivity factor-induced depletion H Xu, ES Svarovskaia, R Barr, Y Zhang, MA Khan, K Strebel, VK Pathak Proceedings of the National Academy of Sciences 101 (15), 5652-5657, 2004 | 298 | 2004 |
HIV-1 uncoats in the nucleus near sites of integration RC Burdick, C Li, MH Munshi, JMO Rawson, K Nagashima, WS Hu, ... Proceedings of the National Academy of Sciences 117 (10), 5486-5493, 2020 | 290 | 2020 |
Recombinant origin of the retrovirus XMRV T Paprotka, KA Delviks-Frankenberry, O Cingöz, A Martinez, HJ Kung, ... Science 333 (6038), 97-101, 2011 | 289 | 2011 |
Guidelines for naming nonprimate APOBEC3 genes and proteins RS LaRue, V Andrésdóttir, Y Blanchard, SG Conticello, D Derse, ... Journal of virology 83 (2), 494-497, 2009 | 289 | 2009 |
Identification of two distinct human immunodeficiency virus type 1 Vif determinants critical for interactions with human APOBEC3G and APOBEC3F RA Russell, VK Pathak Journal of virology 81 (15), 8201-8210, 2007 | 267 | 2007 |
Structure activity of 3-aryl-1, 3-diketo-containing compounds as HIV-1 integrase inhibitors GCG Pais, X Zhang, C Marchand, N Neamati, K Cowansage, ... Journal of medicinal chemistry 45 (15), 3184-3194, 2002 | 265 | 2002 |
High efficiency of HIV-1 genomic RNA packaging and heterozygote formation revealed by single virion analysis J Chen, O Nikolaitchik, J Singh, A Wright, CE Bencsics, JM Coffin, N Ni, ... Proceedings of the National Academy of Sciences 106 (32), 13535-13540, 2009 | 248 | 2009 |
Multiple APOBEC3 restriction factors for HIV-1 and one Vif to rule them all BA Desimmie, KA Delviks-Frankenberrry, RC Burdick, DF Qi, T Izumi, ... Journal of molecular biology 426 (6), 1220-1245, 2014 | 239 | 2014 |
Design of retroviral vectors and helper cells for gene therapy WS Hu, VK Pathak Pharmacological Reviews 52 (4), 493-512, 2000 | 216 | 2000 |
Mechanism for nucleoside analog-mediated abrogation of HIV-1 replication: balance between RNase H activity and nucleotide excision GN Nikolenko, S Palmer, F Maldarelli, JW Mellors, JM Coffin, VK Pathak Proceedings of the National Academy of Sciences 102 (6), 2093-2098, 2005 | 173 | 2005 |
Likely role of APOBEC3G-mediated G-to-A mutations in HIV-1 evolution and drug resistance P Jern, RA Russell, VK Pathak, JM Coffin PLoS pathogens 5 (4), e1000367, 2009 | 170 | 2009 |
P body-associated protein Mov10 inhibits HIV-1 replication at multiple stages R Burdick, JL Smith, C Chaipan, Y Friew, J Chen, NJ Venkatachari, ... Journal of virology 84 (19), 10241-10253, 2010 | 162 | 2010 |
Mutations in the connection domain of HIV-1 reverse transcriptase increase 3′-azido-3′-deoxythymidine resistance GN Nikolenko, KA Delviks-Frankenberry, S Palmer, F Maldarelli, ... Proceedings of the National Academy of Sciences 104 (1), 317-322, 2007 | 159 | 2007 |
Retroviral mutation rates and reverse transcriptase fidelity ES Svarovskaia, SR Cheslock, WH Zhang, WS Hu, VK Pathak Front Biosci 8 (4), d117-134, 2003 | 158 | 2003 |
Structure of the β subunit of translational initiation factor elF-2 VK Pathak, PJ Nielsen, H Trachsel, JWB Hershey Cell 54 (5), 633-639, 1988 | 153 | 1988 |
Azido-containing diketo acid derivatives inhibit human immunodeficiency virus type 1 integrase in vivo and influence the frequency of deletions at two-long-terminal-repeat … ES Svarovskaia, R Barr, X Zhang, GCG Pais, C Marchand, Y Pommier, ... Journal of virology 78 (7), 3210-3222, 2004 | 142 | 2004 |