Anthrax toxin triggers endocytosis of its receptor via a lipid raft–mediated clathrin-dependent process L Abrami, S Liu, P Cosson, SH Leppla, FG van der Goot The Journal of cell biology 160 (3), 321-328, 2003 | 636 | 2003 |
Anthrax lethal factor cleavage of Nlrp1 is required for activation of the inflammasome JL Levinsohn, ZL Newman, KA Hellmich, R Fattah, MA Getz, S Liu, ... PLoS pathogens 8 (3), e1002638, 2012 | 345 | 2012 |
Anthrax pathogenesis M Moayeri, SH Leppla, C Vrentas, AP Pomerantsev, S Liu Annual review of microbiology 69, 185-208, 2015 | 289 | 2015 |
Anthrax lethal and edema toxins in anthrax pathogenesis S Liu, M Moayeri, SH Leppla Trends in microbiology 22 (6), 317-325, 2014 | 248 | 2014 |
Targeting of tumor cells by cell surface urokinase plasminogen activator-dependent anthrax toxin S Liu, TH Bugge, SH Leppla Journal of Biological Chemistry 276 (21), 17976-17984, 2001 | 235 | 2001 |
Cell surface tumor endothelium marker 8 cytoplasmic tail-independent anthrax toxin binding, proteolytic processing, oligomer formation, and internalization S Liu, SH Leppla Journal of Biological Chemistry 278 (7), 5227-5234, 2003 | 202 | 2003 |
Capillary morphogenesis protein-2 is the major receptor mediating lethality of anthrax toxin in vivo S Liu, D Crown, S Miller-Randolph, M Moayeri, H Wang, H Hu, T Morley, ... Proceedings of the National Academy of Sciences 106 (30), 12424-12429, 2009 | 182 | 2009 |
Tumor cell-selective cytotoxicity of matrix metalloproteinase-activated anthrax toxin S Liu, S Netzel-Arnett, H Birkedal-Hansen, SH Leppla Cancer Research 60 (21), 6061-6067, 2000 | 180 | 2000 |
Identification of the proteins required for biosynthesis of diphthamide, the target of bacterial ADP-ribosylating toxins on translation elongation factor 2 S Liu, GT Milne, JG Kuremsky, GR Fink, SH Leppla Molecular and Cellular Biology 24 (21), 9487-9497, 2004 | 179 | 2004 |
Potent antitumor activity of a urokinase-activated engineered anthrax toxin S Liu, H Aaronson, DJ Mitola, SH Leppla, TH Bugge Proceedings of the National Academy of Sciences 100 (2), 657-662, 2003 | 167 | 2003 |
Inflammasome sensor Nlrp1b-dependent resistance to anthrax is mediated by caspase-1, IL-1 signaling and neutrophil recruitment M Moayeri, D Crown, ZL Newman, S Okugawa, M Eckhaus, C Cataisson, ... PLoS pathogens 6 (12), e1001222, 2010 | 144 | 2010 |
Key tissue targets responsible for anthrax-toxin-induced lethality S Liu, Y Zhang, M Moayeri, J Liu, D Crown, RJ Fattah, AN Wein, ZX Yu, ... Nature 501 (7465), 63-68, 2013 | 143 | 2013 |
Identification of a receptor-binding region within domain 4 of the protective antigen component of anthrax toxin M Varughese, AV Teixeira, S Liu, SH Leppla Infection and immunity 67 (4), 1860-1865, 1999 | 142 | 1999 |
Anthrax lethal factor cleaves mouse nlrp1b in both toxin-sensitive and toxin-resistant macrophages KA Hellmich, JL Levinsohn, R Fattah, ZL Newman, N Maier, I Sastalla, ... PloS one 7 (11), e49741, 2012 | 135 | 2012 |
Tumor-associated macrophages derived from circulating inflammatory monocytes degrade collagen through cellular uptake DH Madsen, HJ Jürgensen, MS Siersbæk, DE Kuczek, LG Cloud, S Liu, ... Cell reports 21 (13), 3662-3671, 2017 | 115 | 2017 |
Susceptibility to Anthrax Lethal Toxin-Induced Rat Death Is Controlled by a Single Chromosome 10 Locus That Includes rNlrp1 ZL Newman, MP Printz, S Liu, D Crown, L Breen, S Miller-Randolph, ... PLoS pathogens 6 (5), e1000906, 2010 | 114 | 2010 |
Anthrax toxin targeting of myeloid cells through the CMG2 receptor is essential for establishment of Bacillus anthracis infections in mice S Liu, S Miller-Randolph, D Crown, M Moayeri, I Sastalla, S Okugawa, ... Cell host & microbe 8 (5), 455-462, 2010 | 108 | 2010 |
ATM‐CHK 2‐Beclin 1 axis promotes autophagy to maintain ROS homeostasis under oxidative stress QQ Guo, SS Wang, SS Zhang, HD Xu, XM Li, Y Guan, F Yi, TT Zhou, ... The EMBO Journal 39 (10), e103111, 2020 | 107 | 2020 |
Matrix metalloproteinase-activated anthrax lethal toxin demonstrates high potency in targeting tumor vasculature S Liu, H Wang, BM Currie, A Molinolo, HJ Leung, M Moayeri, JR Basile, ... Journal of biological chemistry 283 (1), 529-540, 2008 | 99 | 2008 |
Selective abrogation of the uPA-uPAR interaction in vivo reveals a novel role in suppression of fibrin-associated inflammation BM Connolly, EY Choi, H Gårdsvoll, AL Bey, BM Currie, T Chavakis, S Liu, ... Blood, The Journal of the American Society of Hematology 116 (9), 1593-1603, 2010 | 98 | 2010 |