Phase I clinical trial of oral rigosertib in patients with myelodysplastic syndromes RS Komrokji, A Raza, JE Lancet, C Ren, D Taft, M Maniar, F Wilhelm, ... British journal of haematology 162 (4), 517-524, 2013 | 68 | 2013 |
The isolated perfused rat kidney model: a useful tool for drug discovery and development DR Taft Current Drug Discovery Technologies 1 (1), 97-111, 2004 | 65 | 2004 |
Advanced drug formulation design to optimize therapeutic outcomes RO Williams, DR Taft, JT McConville CRC Press, 2007 | 48 | 2007 |
Application of physiologically based pharmacokinetic modeling to predict drug disposition in pregnant populations VK Jogiraju, S Avvari, R Gollen, DR Taft Biopharmaceutics & Drug Disposition 38 (7), 426-438, 2017 | 44 | 2017 |
Radioprotective effects of ON 01210. Na upon oral administration S Suman, K Datta, K Doiron, C Ren, R Kumar, DR Taft, AJ Fornace, ... Journal of Radiation Research 53 (3), 368-376, 2012 | 41 | 2012 |
Drug excretion DR Taft Pharmacology, 175-199, 2009 | 41 | 2009 |
Preclinical drug development MC Rogge, DR Taft Drugs and the pharmaceutical sciences 187, 2010 | 40 | 2010 |
Preclinical pharmacokinetics and in vitro activity of ON 01910. Na, a novel anti-cancer agent AW Chun, SC Cosenza, DR Taft, M Maniar Cancer chemotherapy and pharmacology 65, 177-186, 2009 | 40 | 2009 |
A novel HPLC assay for pentamidine: comparative effects of creatinine and inulin on GFR estimation and pentamidine renal excretion in the isolated perfused rat kidney NR Poola, D Bhuiyan, S Ortiz, IA Savant, M Sidhom, DR Taft, ... J Pharm Pharm Sci 5 (2), 135-145, 2002 | 38 | 2002 |
Renal disposition and drug interaction screening of (–)-2′-deoxy-3′-thiacytidine (3TC) in the isolated perfused rat kidney KR Sweeney, PH Hsyu, P Statkevich, DR Taft Pharmaceutical research 12, 1958-1963, 1995 | 37 | 1995 |
Effects of morning versus evening administration of atorvastatin in patients with hyperlipidemia R Plakogiannis, H Cohen, D Taft American journal of health-system pharmacy 62 (23), 2491-2494, 2005 | 35 | 2005 |
Aristolochic acid I metabolism in the isolated perfused rat kidney HA Priestap, MC Torres, RA Rieger, KG Dickman, T Freshwater, DR Taft, ... Chemical Research in Toxicology 25 (1), 130-139, 2012 | 32 | 2012 |
Characterization of pentamidine excretion in the isolated perfused rat kidney NR Poola, M Kalis, FM Plakogiannis, DR Taft Journal of Antimicrobial Chemotherapy 52 (3), 397-404, 2003 | 30 | 2003 |
Application of a first-pass effect model to characterize the pharmacokinetic disposition of venlafaxine after oral administration to human subjects DR Taft, GR Iyer, L Behar, RV Digregorio Drug metabolism and disposition 25 (10), 1215-1218, 1997 | 28 | 1997 |
Phase 1 study of intravenous rigosertib (ON 01910. Na), a novel benzyl styryl sulfone structure producing G2/M arrest and apoptosis, in adult patients with advanced cancer T Ohnuma, D Lehrer, C Ren, SY Cho, M Maniar, L Silverman, M Sung, ... American journal of cancer research 3 (3), 323, 2013 | 25 | 2013 |
Effects of trimethoprim on the clearance of apricitabine, a deoxycytidine analog reverse transcriptase inhibitor, and lamivudine in the isolated perfused rat kidney T Nakatani-Freshwater, M Babayeva, A Dontabhaktuni, DR Taft Journal of Pharmacology and Experimental Therapeutics 319 (2), 941-947, 2006 | 25 | 2006 |
Renal excretion of emtricitabine I: effects of organic anion, organic cation, and nucleoside transport inhibitors on emtricitabine excretion T Nakatani‐Freshwater, DR Taft Journal of pharmaceutical sciences 97 (12), 5401-5410, 2008 | 24 | 2008 |
Real-world experience with higher-than-recommended doses of lamivudine in patients with varying degrees of renal impairment B Fischetti, K Shah, DR Taft, L Berkowitz, A Bakshi, A Cha Open Forum Infectious Diseases 5 (10), ofy225, 2018 | 22 | 2018 |
In vitro evaluation of the release of albuterol sulfate from polymer gels: effect of fatty acids on drug transport across biological membranes MNA Chisty, RA Bellantone, DR Taft, FM Plakogiannis Drug development and industrial pharmacy 28 (10), 1221-1229, 2002 | 20 | 2002 |
The influence of protein binding on the elimination of acetazolamide by the isolated perfused rat kidney: evidence of albumin-mediated tubular secretion. DR Taft, KR Sweeney Journal of Pharmacology and Experimental Therapeutics 274 (2), 752-760, 1995 | 19 | 1995 |