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Schara Safarian
Schara Safarian
Fraunhofer Institut für Translationale Medizin und Pharmakologie ITMP
在 biophys.mpg.de 的电子邮件经过验证
标题
引用次数
引用次数
年份
Structure of a bd oxidase indicates similar mechanisms for membrane-integrated oxygen reductases
S Safarian, C Rajendran, H Müller, J Preu, JD Langer, S Ovchinnikov, ...
Science 352 (6285), 583-586, 2016
1672016
Active site rearrangement and structural divergence in prokaryotic respiratory oxidases
S Safarian, A Hahn, DJ Mills, M Radloff, ML Eisinger, A Nikolaev, ...
Science 366 (6461), 100-104, 2019
1182019
Inward-facing conformation of a multidrug resistance MATE family transporter
S Zakrzewska, AR Mehdipour, VN Malviya, T Nonaka, J Koepke, ...
Proceedings of the National Academy of Sciences 116 (25), 12275-12284, 2019
502019
The cryo-EM structure of the bd oxidase from M. tuberculosis reveals a unique structural framework and enables rational drug design to combat TB
S Safarian, HK Opel-Reading, D Wu, AR Mehdipour, K Hards, LK Harold, ...
Nature Communications 12 (1), 5236, 2021
422021
Structural basis for amino acid exchange by a human heteromeric amino acid transporter
D Wu, TN Grund, S Welsch, DJ Mills, M Michel, S Safarian, H Michel
Proceedings of the National Academy of Sciences 117 (35), 21281-21287, 2020
292020
Cryo-EM structures of intermediates suggest an alternative catalytic reaction cycle for cytochrome c oxidase
F Kolbe, S Safarian, Ż Piórek, S Welsch, H Müller, H Michel
Nature communications 12 (1), 6903, 2021
242021
Mechanistic and structural diversity between cytochrome bd isoforms of Escherichia coli
TN Grund, M Radloff, D Wu, HG Goojani, LF Witte, W Jösting, ...
Proceedings of the National Academy of Sciences 118 (50), e2114013118, 2021
232021
Short-chain aurachin D derivatives are selective inhibitors of E. coli cytochrome bd-I and bd-II oxidases
M Radloff, I Elamri, TN Grund, LF Witte, KF Hohmann, S Nakagaki, ...
Scientific Reports 11 (1), 23852, 2021
102021
Dissecting the conformational complexity and mechanism of a bacterial heme transporter
D Wu, AR Mehdipour, F Finke, HG Goojani, RR Groh, TN Grund, ...
Nature Chemical Biology 19 (8), 992-1003, 2023
72023
Electrocatalytic evidence of the diversity of the oxygen reaction in the bacterial bd oxidase from different organisms
A Nikolaev, S Safarian, A Thesseling, D Wohlwend, T Friedrich, H Michel, ...
Biochimica et Biophysica Acta (BBA)-Bioenergetics 1862 (8), 148436, 2021
72021
The structure of the Aquifex aeolicus MATE family multidrug resistance transporter and sequence comparisons suggest the existence of a new subfamily
J Zhao, H Xie, AR Mehdipour, S Safarian, U Ermler, C Münke, ...
Proceedings of the National Academy of Sciences 118 (46), e2107335118, 2021
62021
The cryoEM structure of cytochrome bd from C. glutamicum provides novel insights into structural properties of actinobacterial terminal oxidases
TN Grund, Y Kabashima, T Kusumoto, D Wu, S Welsch, J Sakamoto, ...
Frontiers in Chemistry 10, 1085463, 2023
42023
Synthesis and Biological Screening of New Lawson Derivatives as Selective Substrate‐Based Inhibitors of Cytochrome bo3 Ubiquinol Oxidase from Escherichia coli
I Elamri, M Radloff, KF Hohmann, VD Nimbarte, HR Nasiri, M Bolte, ...
ChemMedChem 15 (14), 1262-1271, 2020
42020
The Two TpsB-Like Proteins in Anabaena sp. Strain PCC 7120 Are Involved in Secretion of Selected Substrates
G Ngo, M Girbas, H Schätzle, A Hammer, S Safarian, M Hübinger, ...
Journal of Bacteriology 203 (4), 10.1128/jb. 00568-20, 2021
32021
Molecular mechanism of choline and ethanolamine transport in humans
K Ri, TH Weng, A Claveras Cabezudo, W Jösting, Y Zhang, A Bazzone, ...
Nature, 1-8, 2024
22024
Structural and mechanistic insights into human choline and ethanolamine transport
K Ri, TH Weng, A Claveras Cabezudo, W Jösting, Z Yu, A Bazzone, ...
bioRxiv, 2023.09. 15.557925, 2023
22023
Structural and mechanistic insights into human choline transport
TH Weng, A Claveras Cabezudo, W Jösting, A Bazzone, S Welsch, ...
bioRxiv, 2023
2023
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