Beyond hot and spicy: TRPV channels and their pharmacological modulation G Seebohm, JA Schreiber Cell Physiol Biochem 55 (S3), 108-130, 2021 | 44 | 2021 |
A common mechanism allows selective targeting of GluN2B subunit-containing N-methyl-D-aspartate receptors JA Schreiber, D Schepmann, B Frehland, S Thum, M Datunashvili, ... Communications Biology 2 (1), 420, 2019 | 28 | 2019 |
Design, synthesis, pharmacological evaluation and docking studies of GluN2B‐selective NMDA receptor antagonists with a benzo [7] annulen‐7‐amine scaffold S Gawaskar, L Temme, JA Schreiber, D Schepmann, A Bonifazi, D Robaa, ... ChemMedChem 12 (15), 1212-1222, 2017 | 25 | 2017 |
Synthesis and pharmacological evaluation of enantiomerically pure GluN2B selective NMDA receptor antagonists F Börgel, M Szermerski, JA Schreiber, L Temme, N Strutz‐Seebohm, ... ChemMedChem 13 (15), 1580-1587, 2018 | 23 | 2018 |
Ifenprodil stereoisomers: synthesis, absolute configuration, and correlation with biological activity E Bechthold, JA Schreiber, K Lehmkuhl, B Frehland, D Schepmann, ... Journal of Medicinal Chemistry 64 (2), 1170-1179, 2021 | 22 | 2021 |
Comparative pharmacological study of common NMDA receptor open channel blockers regarding their affinity and functional activity toward GluN2A and GluN2B NMDA receptors L Temme, D Schepmann, JA Schreiber, B Frehland, B Wünsch ChemMedChem 13 (5), 446-452, 2018 | 21 | 2018 |
K2P18.1 translates T cell receptor signals into thymic regulatory T cell development T Ruck, S Bock, S Pfeuffer, CB Schroeter, D Cengiz, P Marciniak, ... Cell Research 32 (1), 72-88, 2022 | 20 | 2022 |
Systematic variation of the benzenesulfonamide part of the GluN2A selective NMDA receptor antagonist TCN-201 SL Müller, JA Schreiber, D Schepmann, N Strutz-Seebohm, G Seebohm, ... European Journal of Medicinal Chemistry 129, 124-134, 2017 | 17 | 2017 |
Deconstruction–reconstruction approach to analyze the essential structural elements of tetrahydro-3-benzazepine-based antagonists of GluN2B subunit containing NMDA receptors S Dey, L Temme, JA Schreiber, D Schepmann, B Frehland, K Lehmkuhl, ... European Journal of Medicinal Chemistry 138, 552-564, 2017 | 15 | 2017 |
The ubiquitination landscape of the influenza A virus polymerase F Günl, T Krischuns, JA Schreiber, L Henschel, M Wahrenburg, ... Nature communications 14 (1), 787, 2023 | 13 | 2023 |
Negative allosteric modulators of the GluN2B NMDA receptor with phenylethylamine structure embedded in ring-expanded and ring-contracted scaffolds L Temme, E Bechthold, JA Schreiber, S Gawaskar, D Schepmann, ... European Journal of Medicinal Chemistry 190, 112138, 2020 | 13 | 2020 |
Systematic variation of the benzoylhydrazine moiety of the GluN2A selective NMDA receptor antagonist TCN-201 JA Schreiber, SL Müller, SE Westphälinger, D Schepmann, ... European Journal of Medicinal Chemistry 158, 259-269, 2018 | 11 | 2018 |
A benzodiazepine activator locks Kv7.1 channels open by electro-mechanical uncoupling JA Schreiber, M Möller, M Zaydman, L Zhao, Z Beller, S Becker, N Ritter, ... Communications Biology 5 (1), 301, 2022 | 10 | 2022 |
The special one: architecture, physiology and pharmacology of the TRESK channel JA Schreiber, M Dufer, G Seebohm Cell. Physiol. Biochem 56, 663-684, 2022 | 8 | 2022 |
Effects of axonal demyelination, inflammatory cytokines and divalent cation chelators on thalamic HCN channels and oscillatory bursting T Oniani, L Vinnenberg, R Chaudhary, JA Schreiber, K Riske, B Williams, ... International Journal of Molecular Sciences 23 (11), 6285, 2022 | 7 | 2022 |
Cardiac K+ Channels and Channelopathies JA Schreiber, G Seebohm Pharmacology of Potassium Channels, 113-138, 2021 | 7 | 2021 |
Rottlerin: structure modifications and KCNQ1/KCNE1 ion channel activity M Lübke, JA Schreiber, T Le Quoc, F Körber, J Müller, S Sivanathan, ... ChemMedChem 15 (12), 1078-1088, 2020 | 7 | 2020 |
Stilbenedisulfonic Acid (DIDS) Modulates the Activity of KCNQ1/KCNE1 Channels by an Interaction with the Central Pore Region E Bollmanna, JA Schreibera, N Rittera, S Peischarda, HT Hoa, ... Cell Physiol Biochem 54, 321-332, 2020 | 7 | 2020 |
Synthesis of tropane-based σ1 receptor antagonists with antiallodynic activity E Bechthold, JA Schreiber, N Ritter, L Grey, D Schepmann, C Daniliuc, ... European Journal of Medicinal Chemistry 230, 114113, 2022 | 5 | 2022 |
Deconstruction-reconstruction: analysis of the crucial structural elements of GluN2B-selective, negative allosteric NMDA receptor modulators with 3-benzazepine scaffold N Ritter, M Korff, A Markus, D Schepmann, G Seebohm, JA Schreiber, ... Cell Physiol Biochem 55 (S3), 1-13, 2021 | 5 | 2021 |