Small-molecule proteostasis regulators for protein conformational diseases B Calamini, MC Silva, F Madoux, DM Hutt, S Khanna, MA Chalfant, ... Nature chemical biology 8 (2), 185-196, 2012 | 260 | 2012 |
Protein aggregation can inhibit clathrin-mediated endocytosis by chaperone competition A Yu, Y Shibata, B Shah, B Calamini, DC Lo, RI Morimoto Proceedings of the National Academy of Sciences 111 (15), E1481-E1490, 2014 | 177 | 2014 |
Protein homeostasis as a therapeutic target for diseases of protein conformation B Calamini, R I Morimoto Current topics in medicinal chemistry 12 (22), 2623-2640, 2012 | 117 | 2012 |
Control of the structural landscape and neuronal proteotoxicity of mutant Huntingtin by domains flanking the polyQ tract K Shen, B Calamini, JA Fauerbach, B Ma, SH Shahmoradian, ... Elife 5, e18065, 2016 | 73 | 2016 |
Heat shock response activation exacerbates inclusion body formation in a cellular model of Huntington disease K Bersuker, MS Hipp, B Calamini, RI Morimoto, RR Kopito Journal of Biological Chemistry 288 (33), 23633-23638, 2013 | 63 | 2013 |
IKK/NF-κB signaling contributes to glioblastoma stem cell maintenance AL Rinkenbaugh, PC Cogswell, B Calamini, DE Dunn, AI Persson, ... Oncotarget 7 (43), 69173, 2016 | 54 | 2016 |
IKKβ and mutant huntingtin interactions regulate the expression of IL-34: implications for microglial-mediated neurodegeneration in HD A Khoshnan, A Sabbaugh, B Calamini, SA Marinero, DE Dunn, JH Yoo, ... Human molecular genetics 26 (21), 4267-4277, 2017 | 30 | 2017 |
Experimental models for identifying modifiers of polyglutamine-induced aggregation and neurodegeneration B Calamini, DC Lo, LS Kaltenbach Neurotherapeutics 10 (3), 400-415, 2013 | 12 | 2013 |
ML346: a novel modulator of proteostasis for protein conformational diseases B Calamini, MC Silva, F Madoux, DM Hutt, S Khanna, MA Chalfant, ... Probe Reports from the NIH Molecular Libraries Program [Internet], 2013 | 12 | 2013 |
Method of modulating HSF-1 RI Morimoto, S Westerheide, J Anckar, L Sistonen, B Calamini US Patent 8,551,726, 2013 | 9 | 2013 |
Time-resolved FRET screening identifies small molecular modifiers of mutant Huntingtin conformational inflexibility in patient-derived cells JH Wilbertz, J Frappier, S Muller, S Gratzer, W Englaro, LM Stanek, ... SLAS Discovery 27 (4), 219-228, 2022 | 4 | 2022 |
Development of a physiologically relevant and easily scalable LUHMES cell-based model of G2019S LRRK2-driven Parkinson's disease B Calamini, N Geyer, N Huss-Braun, A Bernhardt, V Harsany, P Rival, ... Disease models & mechanisms 14 (6), dmm048017, 2021 | 3 | 2021 |
Polyglutamine Flanking Regions in Huntingtin Highlight Key Structural Intermediates Relevant for Molecular Chaperone Interaction and Huntington's Disease Pathogenesis K Shen, B Calamini, D Lo, J Frydman Biophysical Journal 106 (2), 682a, 2014 | 1 | 2014 |
Supplementary Figure 3 A Khoshnan, A Sabbaugh, B Calamini, SA Marinero, DE Dunn, JH Yoo, ... | | |
682a Wednesday, February 19, 2014 K Shen, B Calamini, D Lo, J Frydman | | |
SUPPLEMENTARY RESULTS B Calamini, MC Silva, F Madoux, DM Hutt, S Khanna, MA Chalfant, ... | | |