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Barbara Calamini
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Small-molecule proteostasis regulators for protein conformational diseases
B Calamini, MC Silva, F Madoux, DM Hutt, S Khanna, MA Chalfant, ...
Nature chemical biology 8 (2), 185-196, 2012
2602012
Protein aggregation can inhibit clathrin-mediated endocytosis by chaperone competition
A Yu, Y Shibata, B Shah, B Calamini, DC Lo, RI Morimoto
Proceedings of the National Academy of Sciences 111 (15), E1481-E1490, 2014
1772014
Protein homeostasis as a therapeutic target for diseases of protein conformation
B Calamini, R I Morimoto
Current topics in medicinal chemistry 12 (22), 2623-2640, 2012
1172012
Control of the structural landscape and neuronal proteotoxicity of mutant Huntingtin by domains flanking the polyQ tract
K Shen, B Calamini, JA Fauerbach, B Ma, SH Shahmoradian, ...
Elife 5, e18065, 2016
732016
Heat shock response activation exacerbates inclusion body formation in a cellular model of Huntington disease
K Bersuker, MS Hipp, B Calamini, RI Morimoto, RR Kopito
Journal of Biological Chemistry 288 (33), 23633-23638, 2013
632013
IKK/NF-κB signaling contributes to glioblastoma stem cell maintenance
AL Rinkenbaugh, PC Cogswell, B Calamini, DE Dunn, AI Persson, ...
Oncotarget 7 (43), 69173, 2016
542016
IKKβ and mutant huntingtin interactions regulate the expression of IL-34: implications for microglial-mediated neurodegeneration in HD
A Khoshnan, A Sabbaugh, B Calamini, SA Marinero, DE Dunn, JH Yoo, ...
Human molecular genetics 26 (21), 4267-4277, 2017
302017
Experimental models for identifying modifiers of polyglutamine-induced aggregation and neurodegeneration
B Calamini, DC Lo, LS Kaltenbach
Neurotherapeutics 10 (3), 400-415, 2013
122013
ML346: a novel modulator of proteostasis for protein conformational diseases
B Calamini, MC Silva, F Madoux, DM Hutt, S Khanna, MA Chalfant, ...
Probe Reports from the NIH Molecular Libraries Program [Internet], 2013
122013
Method of modulating HSF-1
RI Morimoto, S Westerheide, J Anckar, L Sistonen, B Calamini
US Patent 8,551,726, 2013
92013
Time-resolved FRET screening identifies small molecular modifiers of mutant Huntingtin conformational inflexibility in patient-derived cells
JH Wilbertz, J Frappier, S Muller, S Gratzer, W Englaro, LM Stanek, ...
SLAS Discovery 27 (4), 219-228, 2022
42022
Development of a physiologically relevant and easily scalable LUHMES cell-based model of G2019S LRRK2-driven Parkinson's disease
B Calamini, N Geyer, N Huss-Braun, A Bernhardt, V Harsany, P Rival, ...
Disease models & mechanisms 14 (6), dmm048017, 2021
32021
Polyglutamine Flanking Regions in Huntingtin Highlight Key Structural Intermediates Relevant for Molecular Chaperone Interaction and Huntington's Disease Pathogenesis
K Shen, B Calamini, D Lo, J Frydman
Biophysical Journal 106 (2), 682a, 2014
12014
Supplementary Figure 3
A Khoshnan, A Sabbaugh, B Calamini, SA Marinero, DE Dunn, JH Yoo, ...
682a Wednesday, February 19, 2014
K Shen, B Calamini, D Lo, J Frydman
SUPPLEMENTARY RESULTS
B Calamini, MC Silva, F Madoux, DM Hutt, S Khanna, MA Chalfant, ...
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