| Wnt signaling and colorectal cancer EM Schatoff, BI Leach, LE Dow Current colorectal cancer reports 13 (2), 101-110, 2017 | 321 | 2017 |
| Transplantation of engineered organoids enables rapid generation of metastatic mouse models of colorectal cancer KP O'Rourke, E Loizou, G Livshits, EM Schatoff, T Baslan, E Manchado, ... Nature biotechnology 35 (6), 577-582, 2017 | 228 | 2017 |
| Mechanisms of resistance to systemic therapy in metastatic castration-resistant prostate cancer G Galletti, BI Leach, L Lam, ST Tagawa Cancer treatment reviews 57, 16-27, 2017 | 222 | 2017 |
| Leukemia fusion target AF9 is an intrinsically disordered transcriptional regulator that recruits multiple partners via coupled folding and binding BI Leach, A Kuntimaddi, CR Schmidt, T Cierpicki, SA Johnson, ... Structure 21 (1), 176-183, 2013 | 104 | 2013 |
| CD70 (TNFSF7) is expressed at high prevalence in renal cell carcinomas and is rapidly internalised on antibody binding PJ Adam, JA Terrett, G Steers, L Stockwin, JA Loader, GC Fletcher, LS Lu, ... British journal of cancer 95 (3), 298-306, 2006 | 68 | 2006 |
| Distinct colorectal cancer–associated apc mutations dictate response to tankyrase inhibition EM Schatoff, S Goswami, MP Zafra, M Foronda, M Shusterman, BI Leach, ... Cancer discovery 9 (10), 1358-1371, 2019 | 67 | 2019 |
| NMR measurements reveal the structural basis of transthyretin destabilization by pathogenic mutations BI Leach, X Zhang, JW Kelly, HJ Dyson, PE Wright Biochemistry 57 (30), 4421-4430, 2018 | 43 | 2018 |
| BCOR binding to MLL-AF9 is essential for leukemia via altered EYA1, SIX, and MYC activity CR Schmidt, NJ Achille, A Kuntimaddi, AM Boulton, BI Leach, S Zhang, ... Blood cancer discovery 1 (2), 162-177, 2020 | 18 | 2020 |
| Paramagnetic Fluorinated Nanoemulsions for in vivo F-19 MRI J Rho, E Stares, SR Adams, D Lister, B Leach, ET Ahrens Molecular imaging and biology 22, 665-674, 2020 | 16 | 2020 |
| Metallofluorocarbon nanoemulsion for inflammatory macrophage detection via PET and MRI C Wang, BI Leach, D Lister, SR Adams, H Xu, C Hoh, P McConville, ... Journal of Nuclear Medicine 62 (8), 1146-1153, 2021 | 15 | 2021 |
| Assessing Oximetry Response to Chimeric Antigen Receptor T-cell Therapy against Glioma with 19F MRI in a Murine Model F Chapelin, BI Leach, R Chen, D Lister, K Messer, H Okada, ET Ahrens Radiology: Imaging Cancer 3 (1), e200062, 2021 | 11 | 2021 |
| Click-Ready Perfluorocarbon Nanoemulsion for 19F MRI and Multimodal Cellular Detection AS Perez, J Zhou, B Leach, H Xu, D Lister, SR Adams, ET Ahrens, ... ACS nanoscience Au 2 (2), 102-110, 2021 | 8 | 2021 |
| Tankyrase inhibition sensitizes cells to CDK4 blockade M Foronda, Y Tarumoto, EM Schatoff, BI Leach, BJ Diaz, J Zimmerman, ... PLoS One 14 (12), e0226645, 2019 | 8 | 2019 |
| Importance of a specific amino acid pairing for murine MLL leukemias driven by MLLT1/3 or AFF1/4 AA Lokken, NJ Achille, MJ Chang, JJ Lin, A Kuntimaddi, BI Leach, B Malik, ... Leukemia research 38 (11), 1309-1315, 2014 | 7 | 2014 |
| Method for estimation of apoptotic cell fraction of cytotherapy using in vivo fluorine-19 magnetic resonance: pilot study in a patient with head and neck carcinoma receiving … ET Ahrens, BM Helfer, CF O’Hanlon, DR Lister, JL Bykowski, K Messer, ... Journal for immunotherapy of cancer 11 (6), 2023 | 3 | 2023 |
| Direct binding of BCOR, but Not CBX8, to MLL-AF9 is essential for MLL-AF9 leukemia via regulation of the EYA1/SIX1 gene network JH Bushweller, C Schmidt, N Achille, A Kuntimaddi, A Boulton, B Leach, ... Blood 132, 1316, 2018 | 3 | 2018 |
| Characterization of an amyloidogenic intermediate of transthyretin by NMR relaxation dispersion BI Leach, JA Ferguson, GJ Morgan, X Sun, G Kroon, D Oyen, J Dyson, ... bioRxiv, 2024.02. 16.580707, 2024 | 1 | 2024 |
| Probing the dissociation pathway of a kinetically labile transthyretin mutant X Sun, JA Ferguson, BI Leach, RL Stanfield, HJ Dyson, PE Wright Journal of the American Chemical Society 146 (1), 532-542, 2023 | 1 | 2023 |
| Conformational dynamics of an amyloidogenic intermediate of transthyretin: implications for structural remodeling and amyloid formation BI Leach, JA Ferguson, G Morgan, X Sun, G Kroon, D Oyen, HJ Dyson, ... Journal of Molecular Biology, 168673, 2024 | | 2024 |
| Probing the dissociation and reassembly pathway of an amyloidogenic homotetramer X Sun, JA Ferguson, BI Leach, RL Stanfield, J Dyson, PE Wright Biophysical Journal 123 (3), 312a-313a, 2024 | | 2024 |
