C9orf72 expansion within astrocytes reduces metabolic flexibility in amyotrophic lateral sclerosis SP Allen, B Hall, R Woof, L Francis, N Gatto, AC Shaw, M Myszczynska, ... Brain 142 (12), 3771-3790, 2019 | 82 | 2019 |
Directly converted astrocytes retain the ageing features of the donor fibroblasts and elucidate the astrocytic contribution to human CNS health and disease N Gatto, C Dos Santos Souza, AC Shaw, SM Bell, MA Myszczynska, ... Aging Cell 20 (1), e13281, 2021 | 50 | 2021 |
C9ORF72-derived poly-GA DPRs undergo endocytic uptake in iAstrocytes and spread to motor neurons PM Marchi, L Marrone, L Brasseur, A Coens, CP Webster, L Bousset, ... Life Science Alliance 5 (9), 2022 | 11 | 2022 |
Loss of TMEM106B exacerbates C9ALS/FTD DPR pathology by disrupting autophagosome maturation CS Bauer, CP Webster, AC Shaw, JR Kok, LM Castelli, YH Lin, EF Smith, ... Frontiers in Cellular Neuroscience 16, 1061559, 2022 | 5 | 2022 |
Rare and common genetic determinants of mitochondrial function determine severity but not risk of amyotrophic lateral sclerosis C Harvey, M Weinreich, JAK Lee, AC Shaw, L Ferraiuolo, H Mortiboys, ... Heliyon 10 (3), 2024 | 4 | 2024 |
ULTRASTRUCTURAL LOCALIZATION OF CYTOCHROME-OXIDASE ON MITOCHONDRIAL INNER MEMBRANE AND ON CYTOCHROME-OXIDASE LIPOSOMES K MILLERHAMMON, J Day, A Shaw, P Shaw, M Tobleman, ... TEXAS REPORTS ON BIOLOGY AND MEDICINE 33 (2), 359-359, 1975 | 2 | 1975 |
AFFINITY PURIFIED IGG AS A PROBE FOR DISTRIBUTION AND ACTIVITY OF CYTOCHROME-C OXIDASE IN MITOCHONDRIAL AND CYTOCHROME-C OXIDASE MEMBRANES CR HACKENBROCK, K MILLERHAMMON, A SHAW FEDERATION PROCEEDINGS 34 (3), 487-487, 1975 | 1 | 1975 |
Increasing hexokinase 1 expression improves mitochondrial and glycolytic functional deficits seen in sporadic Alzheimer’s disease astrocytes SM Bell, H Wareing, F Capriglia, R Hughes, K Barnes, A Hamshaw, ... Molecular Psychiatry, 1-14, 2024 | | 2024 |
C9ORF72 patient-derived endothelial cells drive blood-brain barrier disruption and contribute to neurotoxicity A Aragón-González, AC Shaw, JR Kok, FS Roussel, C Santos Souza, ... Fluids and Barriers of the CNS 21 (1), 34, 2024 | | 2024 |
Deep learning modeling of rare noncoding genetic variants in human motor neurons defines CCDC146 as a therapeutic target for ALS S Zhang, T Moll, J Rubin-Sigler, S Tu, S Li, E Yuan, M Liu, A Butt, ... medRxiv, 2024 | | 2024 |
C9orf72-derived poly-GA DPRs undergo endocytic uptake in iNPC-derived astrocytes and spread to motor neurons PM Marchi, L Marrone, L Brasseur, L Bousset, CP Webster, M Destro, ... bioRxiv, 2021.10. 11.463891, 2021 | | 2021 |
Advances in the generation of GMP-compliant protocols for the differentiation of otic progenitors from clinical-grade human pluripotent stem cells (hPSC) AC Shaw, MRB Farr, MN Rivolta HUMAN GENE THERAPY 28 (8), A27-A27, 2017 | | 2017 |
DISTRIBUTION OF CYTOCHROME-OXIDASE IN MITOCHONDRIAL-MEMBRANES DETERMINED WITH FERRITIN-IGG CONJUGATES AND FREEZE-CLEAVING CR HACKENBROCK, K MILLERHAMMON, A SHAW ANATOMICAL RECORD 181 (2), 368-368, 1975 | | 1975 |