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Aino-Maija Leppä
Aino-Maija Leppä
German Cancer Research Institute
在 dkfz.de 的电子邮件经过验证
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引用次数
引用次数
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Phenotype-based drug screening reveals association between venetoclax response and differentiation stage in acute myeloid leukemia
H Kuusanmäki, AM Leppä, P Pölönen, M Kontro, O Dufva, D Deb, ...
Haematologica 105 (3), 708, 2020
1572020
Erythroid/megakaryocytic differentiation confers BCL-XL dependency and venetoclax resistance in acute myeloid leukemia
H Kuusanmäki, O Dufva, M Vähä-Koskela, AM Leppä, J Huuhtanen, ...
Blood, The Journal of the American Society of Hematology 141 (13), 1610-1625, 2023
602023
Combinatorial BCL2 Family Expression in Acute Myeloid Leukemia Stem Cells Predicts Clinical Response to Azacitidine/Venetoclax
A Waclawiczek, AM Leppä, S Renders, K Stumpf, C Reyneri, B Betz, ...
Cancer Discovery 13 (6), 1408-1427, 2023
552023
Multi-parametric single cell evaluation defines distinct drug responses in healthy hematologic cells that are retained in corresponding malignant cell types
MM Majumder, AM Leppä, M Hellesøy, P Dowling, A Malyutina, ...
haematologica 105 (6), 1527, 2020
232020
Frequent whole blood donations select for DNMT3A variants mediating enhanced response to erythropoietin.
D Karpova, HH Encabo, E Donato, I Kotova, S Calderazzo, AM Leppae, ...
medRxiv, 2022
22022
An arms‐race against resistance: leukemic stem cells and lineage plasticity
A Waclawiczek, AM Leppä, S Renders, A Trumpp
Molecular Oncology, 2024
12024
Opsonization-independent antigen-specific recognition by myeloid phagocytes expressing monoclonal antibodies
M Neumaier, S Giesler, V Ast, M Roemer, TD Voß, E Reinz, V Costina, ...
Science Advances 9 (35), eadg1812, 2023
12023
Leukemic Stem Cells of Monocytic AMLs Are Not-Resistant to BCL-2 Inhibition
S Renders, AM Leppä, A Waclawiczek, M Janssen, E Donato, C Reyneri, ...
Blood 138 (Supplement 1), 3469-3469, 2021
12021
A phase 2 study of carfilzomib plus elotuzumab plus dexamethasone for myeloma patients relapsed after 1-3 prior treatment lines
R Silvennoinen, MM Majumder, D Tsallos, H Nahi, P Anttila, A Partanen, ...
Clinical Lymphoma, Myeloma and Leukemia 19 (10), e279-e280, 2019
12019
A High-Throughput Biology Approach to Identify Novel Therapies Specifically Targeting AML Blasts and Leukemic Stem Cells
H Kuusanmäki, AM Leppä, D Deb, CA Heckman
Blood 128 (22), 2755, 2016
12016
PS973 BCL-XL AS A PUTATIVE THERAPY TARGET IN ACUTE ERYTHROID LEUKEMIA
H Kuusanmäki, O Dufva, AM Leppä, P Pölönen, M Heinäniemi, K Porkka, ...
HemaSphere 3 (S1), 438-439, 2019
2019
Simultaneous Monitoring of Drug Responses on Distinct Hematopoietic Cell Populations Allow Assessment of Direct and Indirect Cytotoxic Effects of Targeted Therapies
MM Majumder, AM Leppä, CA Heckman
Blood 128 (22), 3515, 2016
2016
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