T cells in multiple sclerosis and experimental autoimmune encephalomyelitis KHGM JM Fletcher, SJ Lalor, CM Sweeney, N Tubridy Clinical and Experimental Immunology 162 (1), 1-11, 2010 | 1137 | 2010 |
Human CD4+ CD25hi Foxp3+ regulatory T cells are derived by rapid turnover of memory populations in vivo M Vukmanovic-Stejic, Y Zhang, JE Cook, JM Fletcher, A McQuaid, ... The Journal of clinical investigation 116 (9), 2423-2433, 2006 | 613 | 2006 |
CD39+ Foxp3+ regulatory T Cells suppress pathogenic Th17 cells and are impaired in multiple sclerosis JM Fletcher, R Lonergan, L Costelloe, K Kinsella, B Moran, C O'Farrelly, ... The Journal of Immunology 183 (11), 7602-7610, 2009 | 585 | 2009 |
Caspase-1–processed cytokines IL-1β and IL-18 promote IL-17 production by γδ and CD4 T cells that mediate autoimmunity SJ Lalor, LS Dungan, CE Sutton, SA Basdeo, JM Fletcher, KHG Mills The Journal of Immunology 186 (10), 5738-5748, 2011 | 404 | 2011 |
Antigen‐specific T cell suppression by human CD4+CD25+ regulatory T cells LS Taams, M Vukmanovic‐Stejic, J Smith, PJ Dunne, JM Fletcher, ... European journal of immunology 32 (6), 1621-1630, 2002 | 352 | 2002 |
Cytomegalovirus-specific CD4+ T cells in healthy carriers are continuously driven to replicative exhaustion JM Fletcher, M Vukmanovic-Stejic, PJ Dunne, KE Birch, JE Cook, ... The Journal of Immunology 175 (12), 8218-8225, 2005 | 350 | 2005 |
Memory T cell homeostasis and senescence during aging AN Akbar, JM Fletcher Current opinion in immunology 17 (5), 480-485, 2005 | 282 | 2005 |
Cytomegalovirus-infected endothelial cells recruit neutrophils by the secretion of CXC chemokines and transmit virus by direct neutrophil-endothelial cell contact and during … JE Grundy, KM Lawson, LP MacCormac, JM Fletcher, KL Yong Journal of Infectious Diseases 177 (6), 1465-1474, 1998 | 258 | 1998 |
The loss of telomerase activity in highly differentiated CD8+ CD28− CD27− T cells is associated with decreased Akt (Ser473) phosphorylation FJ Plunkett, O Franzese, HM Finney, JM Fletcher, LL Belaramani, ... The Journal of Immunology 178 (12), 7710-7719, 2007 | 254 | 2007 |
Hepatitis C virus-specific Th17 cells are suppressed by virus-induced TGF-β AG Rowan, JM Fletcher, EJ Ryan, B Moran, JE Hegarty, C O'Farrelly, ... The Journal of Immunology 181 (7), 4485-4494, 2008 | 195 | 2008 |
Epstein-Barr virus–specific CD8+ T cells that re-express CD45RA are apoptosis-resistant memory cells that retain replicative potential PJ Dunne, JM Faint, NH Gudgeon, JM Fletcher, FJ Plunkett, MVD Soares, ... Blood, The Journal of the American Society of Hematology 100 (3), 933-940, 2002 | 191 | 2002 |
IL-27 mediates the response to IFN-β therapy in multiple sclerosis patients by inhibiting Th17 cells CM Sweeney, R Lonergan, SA Basdeo, K Kinsella, LS Dungan, ... Brain, behavior, and immunity 25 (6), 1170-1181, 2011 | 177 | 2011 |
Attenuating regulatory T cell induction by TLR agonists through inhibition of p38 MAPK signaling in dendritic cells enhances their efficacy as vaccine adjuvants and cancer … AG Jarnicki, H Conroy, C Brereton, G Donnelly, D Toomey, K Walsh, ... The Journal of Immunology 180 (6), 3797-3806, 2008 | 175 | 2008 |
Hidradenitis suppurativa is characterized by dysregulation of the Th17: Treg cell axis, which is corrected by anti-TNF therapy B Moran, CM Sweeney, R Hughes, A Malara, S Kirthi, AM Tobin, B Kirby, ... Journal of Investigative Dermatology 137 (11), 2389-2395, 2017 | 173 | 2017 |
Differential regulation of human Treg and Th17 cells by fatty acid synthesis and glycolysis D Cluxton, A Petrasca, B Moran, JM Fletcher Frontiers in immunology 10, 115, 2019 | 167 | 2019 |
Ex-Th17 (nonclassical Th1) cells are functionally distinct from classical Th1 and Th17 cells and are not constrained by regulatory T cells SA Basdeo, D Cluxton, J Sulaimani, B Moran, M Canavan, C Orr, ... The Journal of Immunology 198 (6), 2249-2259, 2017 | 152 | 2017 |
Telomere erosion in memory T cells induced by telomerase inhibition at the site of antigenic challenge in vivo JR Reed, M Vukmanovic-Stejic, JM Fletcher, MVD Soares, JE Cook, ... The Journal of experimental medicine 199 (10), 1433-1443, 2004 | 133 | 2004 |
Natural killer cell lysis of cytomegalovirus (CMV)-infected cells correlates with virally induced changes in cell surface lymphocyte function-associated antigen-3 (LFA-3 … JM Fletcher, HG Prentice, JE Grundy The Journal of Immunology 161 (5), 2365-2374, 1998 | 127 | 1998 |
CD141+ myeloid dendritic cells are enriched in healthy human liver A Kelly, R Fahey, JM Fletcher, C Keogh, AG Carroll, R Siddachari, ... Journal of hepatology 60 (1), 135-142, 2014 | 112 | 2014 |
The pathogenesis of Parkinson's disease: a complex interplay between astrocytes, microglia, and T lymphocytes? AN MacMahon Copas, SF McComish, JM Fletcher, MA Caldwell Frontiers in Neurology 12, 666737, 2021 | 109 | 2021 |