MitoCarta3. 0: an updated mitochondrial proteome now with sub-organelle localization and pathway annotations S Rath, R Sharma, R Gupta, T Ast, C Chan, TJ Durham, RP Goodman, ... Nucleic acids research 49 (D1), D1541-D1547, 2021 | 948 | 2021 |
Top down proteomics: facts and perspectives AD Catherman, OS Skinner, NL Kelleher Biochemical and biophysical research communications 445 (4), 683-693, 2014 | 640 | 2014 |
Distinct mitochondrial defects trigger the integrated stress response depending on the metabolic state of the cell E Mick, DV Titov, OS Skinner, R Sharma, AA Jourdain, VK Mootha elife 9, e49178, 2020 | 169 | 2020 |
Genetic screen for cell fitness in high or low oxygen highlights mitochondrial and lipid metabolism IH Jain, SE Calvo, AL Markhard, OS Skinner, TL To, T Ast, VK Mootha Cell 181 (3), 716-727. e11, 2020 | 162 | 2020 |
Top-down characterization of endogenous protein complexes with native proteomics OS Skinner, NA Haverland, L Fornelli, RD Melani, LHF Do Vale, ... Nature chemical biology 14 (1), 36-41, 2018 | 151 | 2018 |
Hepatic NADH reductive stress underlies common variation in metabolic traits RP Goodman, AL Markhard, H Shah, R Sharma, OS Skinner, CB Clish, ... Nature 583 (7814), 122-126, 2020 | 129 | 2020 |
Circulating markers of NADH-reductive stress correlate with mitochondrial disease severity R Sharma, B Reinstadler, K Engelstad, OS Skinner, E Stackowitz, ... The Journal of Clinical Investigation 131 (2), 2021 | 126 | 2021 |
The biosynthesis of methanobactin GE Kenney, LMK Dassama, ME Pandelia, AS Gizzi, RJ Martinie, P Gao, ... Science 359 (6382), 1411-1416, 2018 | 121 | 2018 |
How ubiquitin unfolds after transfer into the gas phase OS Skinner, FW McLafferty, K Breuker Journal of the American Society for Mass Spectrometry 23 (6), 1011-1014, 2012 | 117 | 2012 |
Applying label-free quantitation to top down proteomics I Ntai, K Kim, RT Fellers, OS Skinner, AD Smith IV, BP Early, JP Savaryn, ... Analytical chemistry 86 (10), 4961-4968, 2014 | 112 | 2014 |
An engineered enzyme that targets circulating lactate to alleviate intracellular NADH:NAD+ imbalance A Patgiri, OS Skinner, Y Miyazaki, G Schleifer, E Marutani, H Shah, ... Nature Biotechnology 38 (3), 309-313, 2020 | 108 | 2020 |
Mapping proteoforms and protein complexes from king cobra venom using both denaturing and native top-down proteomics RD Melani, OS Skinner, L Fornelli, GB Domont, PD Compton, NL Kelleher Molecular & Cellular Proteomics 15 (7), 2423-2434, 2016 | 87 | 2016 |
Low-dose rapamycin extends lifespan in a mouse model of mtDNA depletion syndrome SE Siegmund, H Yang, R Sharma, M Javors, O Skinner, V Mootha, ... Human molecular genetics 26 (23), 4588-4605, 2017 | 86 | 2017 |
Metabolic regulation of species-specific developmental rates M Diaz-Cuadros, TP Miettinen, OS Skinner, D Sheedy, CM Díaz-García, ... Nature 613 (7944), 550-557, 2023 | 84 | 2023 |
An informatic framework for decoding protein complexes by top-down mass spectrometry OS Skinner, PC Havugimana, NA Haverland, L Fornelli, BP Early, ... Nature methods 13 (3), 237-240, 2016 | 77 | 2016 |
Defining gas-phase fragmentation propensities of intact proteins during native top-down mass spectrometry NA Haverland, OS Skinner, RT Fellers, AA Tariq, BP Early, RD LeDuc, ... Journal of The American Society for Mass Spectrometry 28 (6), 1203-1215, 2017 | 58 | 2017 |
Analyzing internal fragmentation of electrosprayed ubiquitin ions during beam-type collisional dissociation KR Durbin, OS Skinner, RT Fellers, NL Kelleher Journal of the American Society for Mass Spectrometry 26 (5), 782-787, 2015 | 58 | 2015 |
Loss of LUC7L2 and U1 snRNP subunits shifts energy metabolism from glycolysis to OXPHOS AA Jourdain, BE Begg, E Mick, H Shah, SE Calvo, OS Skinner, R Sharma, ... Molecular cell 81 (9), 1905-1919. e12, 2021 | 51 | 2021 |
Illuminating the dark matter of shotgun proteomics OS Skinner, NL Kelleher Nature biotechnology 33 (7), 717-718, 2015 | 50 | 2015 |
Native GELFrEE: a new separation technique for biomolecular assemblies OS Skinner, LHF Do Vale, AD Catherman, PC Havugimana, MV Sousa, ... Analytical chemistry 87 (5), 3032-3038, 2015 | 49 | 2015 |