| Structural basis for selective inhibition of cyclooxygenase-2 by anti-inflammatory agents RG Kurumbail, AM Stevens, JK Gierse, JJ McDonald, RA Stegeman, ... Nature 384 (6610), 644-648, 1996 | 2407 | 1996 |
| Crystal structure of hemoprotein domain of P450BM-3, a prototype for microsomal P450's KG Ravichandran, SS Boddupalli, CA Hasermann, JA Peterson, ... Science 261 (5122), 731-736, 1993 | 1255 | 1993 |
| Structure and function of cytochromes P450: a comparative analysis of three crystal structures CA Hasemann, RG Kurumbail, SS Boddupalli, JA Peterson, ... Structure 3 (1), 41-62, 1995 | 949 | 1995 |
| The structure of a complex of recombinant hirudin and human α-thrombin TJ Rydel, KG Ravichandran, A Tulinsky, W Bode, R Huber, C Roitsch, ... Science 249 (4966), 277-280, 1990 | 890 | 1990 |
| Molecular docking and high-throughput screening for novel inhibitors of protein tyrosine phosphatase-1B TN Doman, SL McGovern, BJ Witherbee, TP Kasten, R Kurumbail, ... Journal of medicinal chemistry 45 (11), 2213-2221, 2002 | 720 | 2002 |
| Crystal structure and refinement of cytochrome P450terp at 2· 3 Å resolution CA Hasemann, KG Ravichandran, JA Peterson, J Deisenhofer Journal of molecular biology 236 (4), 1169-1185, 1994 | 572 | 1994 |
| A novel mechanism of cyclooxygenase-2 inhibition involving interactions with Ser-530 and Tyr-385 SW Rowlinson, JR Kiefer, JJ Prusakiewicz, JL Pawlitz, KR Kozak, ... Journal of Biological Chemistry 278 (46), 45763-45769, 2003 | 416 | 2003 |
| The novel benzopyran class of selective cyclooxygenase-2 inhibitors. Part 2: The second clinical candidate having a shorter and favorable human half-life JL Wang, D Limburg, MJ Graneto, J Springer, JRB Hamper, S Liao, ... Bioorganic & medicinal chemistry letters 20 (23), 7159-7163, 2010 | 330 | 2010 |
| Structure of the hirugen and hirulog 1 complexes of α-thrombin E Skrzypczak-Jankun, VE Carperos, KG Ravichandran, A Tulinsky, ... Journal of molecular biology 221 (4), 1379-1393, 1991 | 324 | 1991 |
| Structural insights into the stereochemistry of the cyclooxygenase reaction JR Kiefer, JL Pawlitz, KT Moreland, RA Stegeman, WF Hood, JK Gierse, ... Nature 405 (6782), 97-101, 2000 | 301 | 2000 |
| Cyclooxygenase enzymes: catalysis and inhibition RG Kurumbail, JR Kiefer, LJ Marnett Current opinion in structural biology 11 (6), 752-760, 2001 | 300 | 2001 |
| Activation of skeletal muscle AMPK promotes glucose disposal and glucose lowering in non-human primates and mice EC Cokorinos, J Delmore, AR Reyes, B Albuquerque, R Kjøbsted, ... Cell metabolism 25 (5), 1147-1159. e10, 2017 | 267 | 2017 |
| Three-dimensional structure of human cytomegalovirus protease HS Shieh, RG Kurumbail, AM Stevens, RA Stegeman, EJ Sturman, ... Nature 383 (6597), 279-282, 1996 | 201 | 1996 |
| Pyrrolopyridine inhibitors of mitogen-activated protein kinase-activated protein kinase 2 (MK-2) DR Anderson, MJ Meyers, WF Vernier, MW Mahoney, RG Kurumbail, ... Journal of medicinal chemistry 50 (11), 2647-2654, 2007 | 198 | 2007 |
| Structural basis for AMPK activation: natural and synthetic ligands regulate kinase activity from opposite poles by different molecular mechanisms MF Calabrese, F Rajamohan, MS Harris, NL Caspers, R Magyar, ... Structure 22 (8), 1161-1172, 2014 | 193 | 2014 |
| Discovery and Preclinical Profiling of 3-[4-(Morpholin-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]benzonitrile (PF-06447475), a Highly Potent, Selective, Brain Penetrant … JL Henderson, BL Kormos, MM Hayward, KJ Coffman, J Jasti, ... Journal of medicinal chemistry 58 (1), 419-432, 2015 | 191 | 2015 |
| Crystal and molecular structure of human plasminogen kringle 4 refined at 1.9-. ANG. resolution AM Mulichak, A Tulinsky, KG Ravichandran Biochemistry 30 (43), 10576-10588, 1991 | 148 | 1991 |
| Crystal and molecular structure of anthracene and biphenylene pillared cofacial diporphyrins JP Fillers, KG Ravichandran, I Abdalmuhdi, A Tulinsky, CK Chang Journal of the American Chemical Society 108 (3), 417-424, 1986 | 138 | 1986 |
| A three-step kinetic mechanism for selective inhibition of cyclo-oxygenase-2 by diarylheterocyclic inhibitors MC WALKER, RG KURUMBAIL, JR KIEFER, KT MORELAND, ... Biochemical Journal 357 (3), 709-718, 2001 | 127 | 2001 |
| Discovery and Preclinical Characterization of 6-Chloro-5-[4-(1-hydroxycyclobutyl)phenyl]-1H-indole-3-carboxylic Acid (PF-06409577), a Direct Activator of … KO Cameron, DW Kung, AS Kalgutkar, RG Kurumbail, R Miller, CT Salatto, ... Journal of Medicinal Chemistry 59 (17), 8068-8081, 2016 | 125 | 2016 |
