Chondroitinase ABC promotes functional recovery after spinal cord injury EJ Bradbury, LDF Moon, RJ Popat, VR King, GS Bennett, PN Patel, ... Nature 416 (6881), 636-640, 2002 | 2964 | 2002 |
A rapid and transient peripheral inflammatory response precedes brain inflammation after experimental stroke KZ Chapman, VQ Dale, Á Dénes, G Bennett, NJ Rothwell, SM Allan, ... Journal of Cerebral Blood Flow & Metabolism 29 (11), 1764-1768, 2009 | 168 | 2009 |
Nerve growth factor induced hyperalgesia in the rat hind paw is dependent on circulating neutrophils G Bennett, S Al-Rashed, JRS Hoult, SD Brain Pain 77 (3), 315-322, 1998 | 160 | 1998 |
MMAE Delivery Using the Bicycle Toxin Conjugate BT5528 G Bennett, A Brown, G Mudd, P Huxley, K Van Rietschoten, S Pavan, ... Molecular Cancer Therapeutics 19 (7), 1385-1394, 2020 | 95 | 2020 |
Immunoglobulin-like domains define the nerve growth factor binding site of the TrkA receptor PH Holden, V Asopa, AGS Robertson, AR Clarke, S Tyler, GS Bennett, ... Nature biotechnology 15 (7), 668-672, 1997 | 82 | 1997 |
Identification and optimization of EphA2-selective bicycles for the delivery of cytotoxic payloads GE Mudd, A Brown, L Chen, K van Rietschoten, S Watcham, DP Teufel, ... Journal of medicinal chemistry 63 (8), 4107-4116, 2020 | 71 | 2020 |
Identification and structure of the nerve growth factor binding site on TrkA AGS Robertson, MJ Banfield, SJ Allen, JA Dando, GGF Mason, SJ Tyler, ... Biochemical and biophysical research communications 282 (1), 131-141, 2001 | 66 | 2001 |
Bicyclic peptides as a new modality for imaging and targeting of proteins overexpressed by tumors M Eder, S Pavan, U Bauder-Wüst, K van Rietschoten, AC Baranski, ... Cancer Research 79 (4), 841-852, 2019 | 51 | 2019 |
Neurogenic cutaneous vasodilatation and plasma extravasation in diabetic rats: effect of insulin and nerve growth factor GS Bennett, NE Garrett, LT Diemel, SD Brain, DR Tomlinson British journal of pharmacology 124 (7), 1573-1579, 1998 | 48 | 1998 |
Stable and long-lasting, novel bicyclic peptide plasma kallikrein inhibitors for the treatment of diabetic macular edema DP Teufel, G Bennett, H Harrison, K Van Rietschoten, S Pavan, C Stace, ... Journal of Medicinal Chemistry 61 (7), 2823-2836, 2018 | 47 | 2018 |
Achieving multi-isoform PI3K inhibition in a series of substituted 3, 4-dihydro-2H-benzo [1, 4] oxazines B Perry, R Alexander, G Bennett, G Buckley, T Ceska, T Crabbe, V Dale, ... Bioorganic & medicinal chemistry letters 18 (16), 4700-4704, 2008 | 39 | 2008 |
BT8009; a nectin-4 targeting bicycle toxin conjugate for treatment of solid tumors M Rigby, G Bennett, L Chen, GE Mudd, H Harrison, PJ Beswick, ... Molecular Cancer Therapeutics 21 (12), 1747-1756, 2022 | 31 | 2022 |
Neurogenic oedema and vasodilatation: effect of a selective neuronal NO inhibitor PK Towler, GS Bennett, PK Moore, SD Brain Neuroreport 9 (7), 1513-1518, 1998 | 27 | 1998 |
Development of a LC–MS/MS method for the quantification of toxic payload DM1 cleaved from BT1718 in a Phase I study C Gowland, P Berry, J Errington, P Jeffrey, G Bennett, L Godfrey, ... Bioanalysis 13 (2), 101-113, 2021 | 24 | 2021 |
Development of BT1718, a novel Bicycle Drug Conjugate for the treatment of lung cancer G Bennett, R Lutz, P Park, H Harrison, K Lee Cancer Research 77 (13_Supplement), 1167-1167, 2017 | 22 | 2017 |
Compounds for treating cancer G Bennett, DP Teufel US Patent 10,624,968, 2020 | 21 | 2020 |
Pharmacokinetic (PK) assessment of BT1718: A phase I/II a study of BT1718, a first in class bicycle toxin conjugate (BTC), in patients (pts) with advanced solid tumours N Cook, U Banerji, J Evans, A Biondo, T Germetaki, M Randhawa, ... Annals of Oncology 30, v174, 2019 | 21 | 2019 |
Methods for treating cancer G Bennett, DP Teufel US Patent 10,441,663, 2019 | 20 | 2019 |
CZ415, a Highly Selective mTOR Inhibitor Showing in Vivo Efficacy in a Collagen Induced Arthritis Model AD Cansfield, T Ladduwahetty, M Sunose, K Ellard, R Lynch, AL Newton, ... ACS Medicinal Chemistry Letters 7 (8), 768-773, 2016 | 19 | 2016 |
Optimization of a series of multi-isoform PI3 kinase inhibitors B Perry, R Beevers, G Bennett, G Buckley, T Crabbe, L Gowers, L James, ... Bioorganic & medicinal chemistry letters 18 (19), 5299-5302, 2008 | 18 | 2008 |