关注
Gavin Bennett
Gavin Bennett
BicycleTx Ltd
在 bicycletx.com 的电子邮件经过验证
标题
引用次数
引用次数
年份
Chondroitinase ABC promotes functional recovery after spinal cord injury
EJ Bradbury, LDF Moon, RJ Popat, VR King, GS Bennett, PN Patel, ...
Nature 416 (6881), 636-640, 2002
29642002
A rapid and transient peripheral inflammatory response precedes brain inflammation after experimental stroke
KZ Chapman, VQ Dale, Á Dénes, G Bennett, NJ Rothwell, SM Allan, ...
Journal of Cerebral Blood Flow & Metabolism 29 (11), 1764-1768, 2009
1682009
Nerve growth factor induced hyperalgesia in the rat hind paw is dependent on circulating neutrophils
G Bennett, S Al-Rashed, JRS Hoult, SD Brain
Pain 77 (3), 315-322, 1998
1601998
MMAE Delivery Using the Bicycle Toxin Conjugate BT5528
G Bennett, A Brown, G Mudd, P Huxley, K Van Rietschoten, S Pavan, ...
Molecular Cancer Therapeutics 19 (7), 1385-1394, 2020
952020
Immunoglobulin-like domains define the nerve growth factor binding site of the TrkA receptor
PH Holden, V Asopa, AGS Robertson, AR Clarke, S Tyler, GS Bennett, ...
Nature biotechnology 15 (7), 668-672, 1997
821997
Identification and optimization of EphA2-selective bicycles for the delivery of cytotoxic payloads
GE Mudd, A Brown, L Chen, K van Rietschoten, S Watcham, DP Teufel, ...
Journal of medicinal chemistry 63 (8), 4107-4116, 2020
712020
Identification and structure of the nerve growth factor binding site on TrkA
AGS Robertson, MJ Banfield, SJ Allen, JA Dando, GGF Mason, SJ Tyler, ...
Biochemical and biophysical research communications 282 (1), 131-141, 2001
662001
Bicyclic peptides as a new modality for imaging and targeting of proteins overexpressed by tumors
M Eder, S Pavan, U Bauder-Wüst, K van Rietschoten, AC Baranski, ...
Cancer Research 79 (4), 841-852, 2019
512019
Neurogenic cutaneous vasodilatation and plasma extravasation in diabetic rats: effect of insulin and nerve growth factor
GS Bennett, NE Garrett, LT Diemel, SD Brain, DR Tomlinson
British journal of pharmacology 124 (7), 1573-1579, 1998
481998
Stable and long-lasting, novel bicyclic peptide plasma kallikrein inhibitors for the treatment of diabetic macular edema
DP Teufel, G Bennett, H Harrison, K Van Rietschoten, S Pavan, C Stace, ...
Journal of Medicinal Chemistry 61 (7), 2823-2836, 2018
472018
Achieving multi-isoform PI3K inhibition in a series of substituted 3, 4-dihydro-2H-benzo [1, 4] oxazines
B Perry, R Alexander, G Bennett, G Buckley, T Ceska, T Crabbe, V Dale, ...
Bioorganic & medicinal chemistry letters 18 (16), 4700-4704, 2008
392008
BT8009; a nectin-4 targeting bicycle toxin conjugate for treatment of solid tumors
M Rigby, G Bennett, L Chen, GE Mudd, H Harrison, PJ Beswick, ...
Molecular Cancer Therapeutics 21 (12), 1747-1756, 2022
312022
Neurogenic oedema and vasodilatation: effect of a selective neuronal NO inhibitor
PK Towler, GS Bennett, PK Moore, SD Brain
Neuroreport 9 (7), 1513-1518, 1998
271998
Development of a LC–MS/MS method for the quantification of toxic payload DM1 cleaved from BT1718 in a Phase I study
C Gowland, P Berry, J Errington, P Jeffrey, G Bennett, L Godfrey, ...
Bioanalysis 13 (2), 101-113, 2021
242021
Development of BT1718, a novel Bicycle Drug Conjugate for the treatment of lung cancer
G Bennett, R Lutz, P Park, H Harrison, K Lee
Cancer Research 77 (13_Supplement), 1167-1167, 2017
222017
Compounds for treating cancer
G Bennett, DP Teufel
US Patent 10,624,968, 2020
212020
Pharmacokinetic (PK) assessment of BT1718: A phase I/II a study of BT1718, a first in class bicycle toxin conjugate (BTC), in patients (pts) with advanced solid tumours
N Cook, U Banerji, J Evans, A Biondo, T Germetaki, M Randhawa, ...
Annals of Oncology 30, v174, 2019
212019
Methods for treating cancer
G Bennett, DP Teufel
US Patent 10,441,663, 2019
202019
CZ415, a Highly Selective mTOR Inhibitor Showing in Vivo Efficacy in a Collagen Induced Arthritis Model
AD Cansfield, T Ladduwahetty, M Sunose, K Ellard, R Lynch, AL Newton, ...
ACS Medicinal Chemistry Letters 7 (8), 768-773, 2016
192016
Optimization of a series of multi-isoform PI3 kinase inhibitors
B Perry, R Beevers, G Bennett, G Buckley, T Crabbe, L Gowers, L James, ...
Bioorganic & medicinal chemistry letters 18 (19), 5299-5302, 2008
182008
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