Cell-Free Biosynthesis to Evaluate Lasso Peptide Formation and Enzyme–Substrate Tolerance Y Si, AM Kretsch, LM Daigh, MJ Burk, DA Mitchell Journal of the American Chemical Society 143 (15), 5917-5927, 2021 | 49 | 2021 |
Antibacterial activity and mode of action of a sulfonamide-based class of oxaborole leucyl-tRNA-synthetase inhibitors Y Si, S Basak, Y Li, J Merino, JN Iuliano, SG Walker, PJ Tonge ACS infectious diseases 5 (7), 1231-1238, 2019 | 31 | 2019 |
Functional elucidation of TfuA in peptide backbone thioamidation A Liu, Y Si, SH Dong, N Mahanta, HN Penkala, SK Nair, DA Mitchell Nature chemical biology 17 (5), 585-592, 2021 | 23 | 2021 |
Positron Emission Tomography Imaging of Staphylococcus aureus Infection Using a Nitro-Prodrug Analogue of 2-[18F]F-p-Aminobenzoic Acid Y Li, F Daryaee, GE Yoon, D Noh, PM Smith-Jones, Y Si, SG Walker, ... ACS infectious diseases 6 (8), 2249-2259, 2020 | 16 | 2020 |
Peptidase activation by a leader peptide-bound RiPP recognition element AM Kretsch, MG Gadgil, AJ DiCaprio, SE Barrett, BL Kille, Y Si, L Zhu, ... Biochemistry 62 (4), 956-967, 2023 | 15 | 2023 |
Structure-based design, synthesis, and biological evaluation of non-acyl sulfamate inhibitors of the adenylate-forming enzyme MenE CE Evans, Y Si, JS Matarlo, Y Yin, JB French, PJ Tonge, DS Tan Biochemistry 58 (14), 1918-1930, 2019 | 4 | 2019 |
Heterobivalent Inhibitors of Acetyl-CoA Carboxylase: Drug Target Residence Time and Time-Dependent Antibacterial Activity MT Cifone, YL He, R Basu, N Wang, S Davoodi, LA Spagnuolo, Y Si, ... Journal of medicinal chemistry 65 (24), 16510-16525, 2022 | 1 | 2022 |
Inhibitors of adenylate-forming enzyme mene DS Tan, CE Evans, PJ Tonge, ML Boby, Y Si US Patent App. 17/429,319, 2022 | | 2022 |
Development and MOA Study of Antimicrobial Agents Inhibiting Selected Protein Targets Y Si State University of New York at Stony Brook, 2018 | | 2018 |
Analogs of methyl 4-(4-chlorophenyl)-4-oxobut-2-enoate that inhibit MenB in the bacterial menaquinone biosynthesis pathway Y Si, J Matarlo, F Daryaee, P Tonge ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 253, 2017 | | 2017 |