An integrative approach to ortholog prediction for disease-focused and other functional studies Y Hu, I Flockhart, A Vinayagam, C Bergwitz, B Berger, N Perrimon, ... BMC bioinformatics 12, 1-16, 2011 | 700 | 2011 |
FlyBase at 25: looking to the future LS Gramates, SJ Marygold, G Santos, JM Urbano, G Antonazzo, ... Nucleic acids research, gkw1016, 2016 | 614 | 2016 |
The transgenic RNAi project at Harvard Medical School: resources and validation LA Perkins, L Holderbaum, R Tao, Y Hu, R Sopko, K McCall, ... Genetics 201 (3), 843-852, 2015 | 607 | 2015 |
High-resolution DNA-binding specificity analysis of yeast transcription factors C Zhu, KJRP Byers, RP McCord, Z Shi, MF Berger, DE Newburger, ... Genome research 19 (4), 556-566, 2009 | 489 | 2009 |
Fast high-resolution miniature two-photon microscopy for brain imaging in freely behaving mice W Zong, R Wu, M Li, Y Hu, Y Li, J Li, H Rong, H Wu, Y Xu, Y Lu, H Jia, ... Nature methods 14 (7), 713-719, 2017 | 465 | 2017 |
Optimized gene editing technology for Drosophila melanogaster using germ line-specific Cas9 X Ren, J Sun, BE Housden, Y Hu, C Roesel, S Lin, LP Liu, Z Yang, D Mao, ... Proceedings of the National Academy of Sciences 110 (47), 19012-19017, 2013 | 425 | 2013 |
Next-generation high-density self-assembling functional protein arrays N Ramachandran, JV Raphael, E Hainsworth, G Demirkan, MG Fuentes, ... Nature methods 5 (6), 535-538, 2008 | 397 | 2008 |
Proteome-scale purification of human proteins from bacteria P Braun, Y Hu, B Shen, A Halleck, M Koundinya, E Harlow, J LaBaer Proceedings of the National Academy of Sciences 99 (5), 2654-2659, 2002 | 358 | 2002 |
Enhanced specificity and efficiency of the CRISPR/Cas9 system with optimized sgRNA parameters in Drosophila X Ren, Z Yang, J Xu, J Sun, D Mao, Y Hu, SJ Yang, HH Qiao, X Wang, ... Cell reports 9 (3), 1151-1162, 2014 | 336 | 2014 |
Genetic architecture of subcortical brain structures in 38,851 individuals CL Satizabal, HHH Adams, DP Hibar, CC White, MJ Knol, JL Stein, ... Nature genetics 51 (11), 1624-1636, 2019 | 259 | 2019 |
Controllability analysis of the directed human protein interaction network identifies disease genes and drug targets A Vinayagam, TE Gibson, HJ Lee, B Yilmazel, C Roesel, Y Hu, Y Kwon, ... Proceedings of the National Academy of Sciences 113 (18), 4976-4981, 2016 | 250 | 2016 |
Systemic organ wasting induced by localized expression of the secreted insulin/IGF antagonist ImpL2 Y Kwon, W Song, IA Droujinine, Y Hu, JM Asara, N Perrimon Developmental cell 33 (1), 36-46, 2015 | 238 | 2015 |
A gene-specific T2A-GAL4 library for Drosophila PT Lee, J Zirin, O Kanca, WW Lin, KL Schulze, D Li-Kroeger, R Tao, ... elife 7, e35574, 2018 | 226 | 2018 |
A cell atlas of the adult Drosophila midgut RJ Hung, Y Hu, R Kirchner, Y Liu, C Xu, A Comjean, SG Tattikota, F Li, ... Proceedings of the National Academy of Sciences 117 (3), 1514-1523, 2020 | 208 | 2020 |
MARRVEL: integration of human and model organism genetic resources to facilitate functional annotation of the human genome J Wang, R Al-Ouran, Y Hu, SY Kim, YW Wan, MF Wangler, S Yamamoto, ... The American Journal of Human Genetics 100 (6), 843-853, 2017 | 182 | 2017 |
Functional screening in Drosophila identifies Alzheimer's disease susceptibility genes and implicates Tau-mediated mechanisms JM Shulman, S Imboywa, N Giagtzoglou, MP Powers, Y Hu, D Devenport, ... Human molecular genetics, ddt478, 2013 | 162 | 2013 |
FlyPrimerBank: An Online Database for Drosophila melanogaster Gene Expression Analysis and Knockdown Evaluation of RNAi Reagents Y Hu, R Sopko, M Foos, C Kelley, I Flockhart, N Ammeux, X Wang, ... G3: Genes, Genomes, Genetics 3 (9), 1607-1616, 2013 | 155 | 2013 |
Integrating protein-protein interaction networks with phenotypes reveals signs of interactions A Vinayagam, J Zirin, C Roesel, Y Hu, B Yilmazel, AA Samsonova, ... Nature methods 11 (1), 94-99, 2014 | 154 | 2014 |
A single-cell survey of Drosophila blood SG Tattikota, B Cho, Y Liu, Y Hu, V Barrera, MJ Steinbaugh, SH Yoon, ... Elife 9, e54818, 2020 | 149 | 2020 |
Proteomic mapping in live Drosophila tissues using an engineered ascorbate peroxidase CL Chen, Y Hu, ND Udeshi, TY Lau, F Wirtz-Peitz, L He, AY Ting, SA Carr, ... Proceedings of the National Academy of Sciences 112 (39), 12093-12098, 2015 | 144 | 2015 |