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Julia Gardner
Julia Gardner
在 pennmedicine.upenn.edu 的电子邮件经过验证
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引用次数
引用次数
年份
GPCR systems pharmacology: a different perspective on the development of biased therapeutics
DS Eiger, U Pham, J Gardner, C Hicks, S Rajagopal
American Journal of Physiology-Cell Physiology 322 (5), C887-C895, 2022
392022
Biased agonism at chemokine receptors
DS Eiger, N Boldizsar, CC Honeycutt, J Gardner, S Rajagopal
Cellular signalling 78, 109862, 2021
362021
Location bias contributes to functionally selective responses of biased CXCR3 agonists
DS Eiger, N Boldizsar, CC Honeycutt, J Gardner, S Kirchner, C Hicks, ...
Nature Communications 13 (1), 5846, 2022
332022
Phosphorylation barcodes direct biased chemokine signaling at CXCR3
DS Eiger, JS Smith, T Shi, TM Stepniewski, CF Tsai, C Honeycutt, ...
Cell chemical biology 30 (4), 362-382. e8, 2023
162023
Location bias: a “hidden variable” in GPCR pharmacology
DS Eiger, C Hicks, J Gardner, U Pham, S Rajagopal
Bioessays 45 (11), 2300123, 2023
132023
GPCR kinases differentially modulate biased signaling downstream of CXCR3 depending on their subcellular localization
J Gardner, DS Eiger, C Hicks, I Choi, U Pham, A Chundi, O Namjoshi, ...
Science signaling 17 (823), eadd9139, 2024
72024
ACKR3 Proximity Labeling Identifies Novel G protein-and β-arrestin-independent GPCR Interacting Proteins
C Hicks, J Gardner, DS Eiger, ND Camarda, U Pham, S Dhar, ...
bioRxiv, 2024
12024
Subcellular localization of GPCR kinases differentially modulate biased signaling at CXCR3
J Gardner, DS Eiger, C Hicks, I Choi, U Pham, S Rajagopal
bioRxiv, 2022.07. 11.499601, 2022
12022
Location-biased β-arrestin conformations direct GPCR signaling
U Pham, A Chundi, TM Stępniewski, S Darbha, DS Eiger, S Gazula, ...
bioRxiv, 2024
2024
Advances in GPCRs: Structure, Mechanisms, Disease, and Pharmacology: GPCR systems pharmacology: a different perspective on the development of biased therapeutics
DS Eiger, U Pham, J Gardner, C Hicks, S Rajagopal
American Journal of Physiology-Cell Physiology 322 (5), C887, 2022
2022
Phosphorylation barcode ensembles encoded by biased CXCR3 agonists direct non‐redundant chemokine signaling
DS Eiger, J Smith, T Shi, TM Stepniewski, C Honeycutt, N Boldizsar, ...
The FASEB Journal 36, 2022
2022
Location Bias of G Protein‐Coupled Receptor Kinases Promotes Biased Signaling at CXCR3
CN Hicks, D Eiger, J Gardner, N Boldizsar, C Honeycutt, I Choi, ...
The FASEB Journal 36, 2022
2022
Location Bias Contributes to Functionally Selective Responses of Biased CXCR3 Agonists to Regulate Inflammation
J Gardner, D Eiger, N Boldizsar, CC Honeycutt, S Kirchner, C Hicks, ...
The FASEB Journal 36, 2022
2022
LIMPING THROUGH A DIFFERENTIAL: AN UNCOMMON PRESENTATION TO A COMMON PEDIATRIC DIAGNOSIS
J Smith, J Gardner, K Dreher, S Sanders
JOURNAL OF INVESTIGATIVE MEDICINE 70 (1), 219-219, 2022
2022
Differential GRK Recruitment and the Phosphorylation Barcode as a Mechanism for Biased Agonism at G Protein‐Coupled Receptors
J Gardner, D Eiger, C Honeycutt, N Boldizsar, I Choi, S Rajagopal
The FASEB Journal 35, 2021
2021
Receptor Endocytosis as a Mechanism of Biased Agonism at CXCR3
N Boldizsar, D Eiger, C Honeycutt, J Gardner, S Rajagopal
The FASEB Journal 35, 2021
2021
Sympathetic and Parasympathetic Regulation of NF‐κB by GPCRs through the modulation of interactions between p65/RelA and the β‐arrestins
C Honeycutt, D Eiger, N Boldizsar, J Gardner, S Rajagopal
The FASEB Journal 35, 2021
2021
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DS Eiger, U Pham, J Gardner, C Hicks, S Rajagopal, S Rajagopal
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