| Conversion of p35 to p25 deregulates Cdk5 activity and promotes neurodegeneration GN Patrick, L Zukerberg, M Nikolic, S de La Monte, P Dikkes, LH Tsai Nature 402 (6762), 615-622, 1999 | 1942 | 1999 |
| Cables links Cdk5 and c-Abl and facilitates Cdk5 tyrosine phosphorylation, kinase upregulation, and neurite outgrowth LR Zukerberg, GN Patrick, M Nikolic, S Humbert, CL Wu, LM Lanier, ... Neuron 26 (3), 633-646, 2000 | 492 | 2000 |
| p35, the neuronal-specific activator of cyclin-dependent kinase 5 (Cdk5) is degraded by the ubiquitin-proteasome pathway GN Patrick, P Zhou, YT Kwon, PM Howley, LH Tsai Journal of Biological Chemistry 273 (37), 24057-24064, 1998 | 402 | 1998 |
| Regulation of the proteasome by neuronal activity and calcium/calmodulin-dependent protein kinase II SN Djakovic, LA Schwarz, B Barylko, GN DeMartino, GN Patrick Journal of Biological Chemistry 284 (39), 26655-26665, 2009 | 275 | 2009 |
| Ubiquitin-mediated proteasome activity is required for agonist-induced endocytosis of GluRs GN Patrick, B Bingol, HA Weld, EM Schuman Current Biology 13 (23), 2073-2081, 2003 | 247 | 2003 |
| Activity-dependent ubiquitination of GluA1 mediates a distinct AMPA receptor endocytosis and sorting pathway LA Schwarz, BJ Hall, GN Patrick Journal of Neuroscience 30 (49), 16718-16729, 2010 | 223 | 2010 |
| Activity-dependent growth of new dendritic spines is regulated by the proteasome AM Hamilton, WC Oh, H Vega-Ramirez, IS Stein, JW Hell, GN Patrick, ... Neuron 74 (6), 1023-1030, 2012 | 183 | 2012 |
| Activity-dependent trafficking of lysosomes in dendrites and dendritic spines MS Goo, L Sancho, N Slepak, D Boassa, TJ Deerinck, MH Ellisman, ... Journal of Cell Biology 216 (8), 2499-2513, 2017 | 178 | 2017 |
| Regulation of synaptic structure by ubiquitin C-terminal hydrolase L1 AE Cartier, SN Djakovic, A Salehi, SM Wilson, E Masliah, GN Patrick Journal of Neuroscience 29 (24), 7857-7868, 2009 | 170 | 2009 |
| Phosphorylation of Rpt6 regulates synaptic strength in hippocampal neurons SN Djakovic, EM Marquez-Lona, SK Jakawich, R Wright, C Chu, ... Journal of Neuroscience 32 (15), 5126-5131, 2012 | 136 | 2012 |
| Synapse formation and plasticity: recent insights from the perspective of the ubiquitin proteasome system GN Patrick Current opinion in neurobiology 16 (1), 90-94, 2006 | 114 | 2006 |
| p25 protein in neurodegeneration GN Patrick, L Zukerberg, M Nikolic, S de La Monte, P Dikkes, LH Tsai Nature 411 (6839), 764-765, 2001 | 111 | 2001 |
| Mammalian Cdk5 is a functional homologue of the budding yeast Pho85 cyclin-dependent protein kinase D Huang, G Patrick, J Moffat, LH Tsai, B Andrews Proceedings of the National Academy of Sciences 96 (25), 14445-14450, 1999 | 102 | 1999 |
| Mice lacking doublecortin and doublecortin-like kinase 2 display altered hippocampal neuronal maturation and spontaneous seizures G Kerjan, H Koizumi, EB Han, CM Dubé, SN Djakovic, GN Patrick, ... Proceedings of the National Academy of Sciences 106 (16), 6766-6771, 2009 | 92 | 2009 |
| Synaptic strength is bidirectionally controlled by opposing activity-dependent regulation of Nedd4-1 and USP8 SL Scudder, MS Goo, AE Cartier, A Molteni, LA Schwarz, R Wright, ... Journal of Neuroscience 34 (50), 16637-16649, 2014 | 87 | 2014 |
| Differential effects of UCHL1 modulation on alpha-synuclein in PD-like models of alpha-synucleinopathy AE Cartier, K Ubhi, B Spencer, RA Vazquez-Roque, KA Kosberg, ... PLoS One 7 (4), e34713, 2012 | 83 | 2012 |
| Aβ-induced synaptic alterations require the E3 ubiquitin ligase Nedd4-1 EM Rodrigues, SL Scudder, MS Goo, GN Patrick Journal of Neuroscience 36 (5), 1590-1595, 2016 | 70 | 2016 |
| Ubiquitin-dependent trafficking and turnover of ionotropic glutamate receptors MS Goo, SL Scudder, GN Patrick Frontiers in molecular neuroscience 8, 60, 2015 | 66 | 2015 |
| Ubiquitin-dependent endocytosis, trafficking and turnover of neuronal membrane proteins LA Schwarz, GN Patrick Molecular and Cellular Neuroscience 49 (3), 387-393, 2012 | 62 | 2012 |
| Regulation of STIM1 and SOCE by the ubiquitin-proteasome system (UPS) JM Keil, Z Shen, SP Briggs, GN Patrick PLoS One 5 (10), e13465, 2010 | 58 | 2010 |
