关注
Kavitha Gnanasambandan
Kavitha Gnanasambandan
NYU Langone Medical Center
在 med.nyu.edu 的电子邮件经过验证
标题
引用次数
引用次数
年份
Molecular basis for pseudokinase-dependent autoinhibition of JAK2 tyrosine kinase
Y Shan, K Gnanasambandan, D Ungureanu, ET Kim, H Hammarén, ...
Nature structural & molecular biology 21 (7), 579-584, 2014
1682014
Whole-exome sequencing in evaluation of patients with venous thromboembolism
EJ Lee, DJ Dykas, AD Leavitt, RM Camire, E Ebberink, P García de Frutos, ...
Blood advances 1 (16), 1224-1237, 2017
692017
Structure and activation of MuSK, a receptor tyrosine kinase central to neuromuscular junction formation
SR Hubbard, K Gnanasambandan
Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1834 (10), 2166-2169, 2013
592013
The constitutive activation of Jak2-V617F is mediated by a π stacking mechanism involving phenylalanines 595 and 617
K Gnanasambandan, A Magis, PP Sayeski
Biochemistry 49 (46), 9972-9984, 2010
502010
A structure-function perspective of Jak2 mutations and implications for alternate drug design strategies: the road not taken
K Gnanasambandan, PP Sayeski
Current medicinal chemistry 18 (30), 4659-4673, 2011
412011
Phosphorylation of Y372 is critical for Jak2 tyrosine kinase activation
J Sayyah, K Gnanasambandan, S Kamarajugadda, S Tsuda, ...
Cellular signalling 23 (11), 1806-1815, 2011
92011
A shift in the salt bridge interaction of residues D620 and E621 mediates the constitutive activation of Jak2-H538Q/K539L
K Gnanasambandan, AT Magis, PP Sayeski
Molecular and cellular biochemistry 367, 125-140, 2012
72012
Hammaré n
Y Shan, K Gnanasambandan, D Ungureanu, ET Kim
H., Yamashita, K., Silvennoinen, O., Shaw, DE, and Hubbard, SR, 579-584, 2014
52014
Whole Exome Sequencing and Extended Thrombophilia Testing in Patients with Venous Thromboembolism
LM Shevell, EJ Lee, R Dhodapkar, D Dykas, A Popa, D Ma, N Bar, ...
Blood 132, 2506, 2018
12018
Jak2 Plays a Critical and Non-Redundant Role In Hematopoiesis throughout Pre-and Post-Natal Life
S Park, K Gnanasambandan, PP Sayeski
Blood, The Journal of the American Society of Hematology 116 (21), 2238-2238, 2010
12010
Atomic model for janus kinase-2 (jak2) and uses thereof
S Hubbard, K Gnanasambandan, Y Shan
US Patent App. 15/112,235, 2018
2018
Phosphorylation of Y372 is critical for ligand mediated Jak2 tyrosine kinase activation
K Gnanasambandan, J Sayyah, S Kamarajugudda, S Tsuda, ...
The FASEB Journal 25, 558.1-558.1, 2011
2011
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