Enhancement of trans-cleavage activity of Cas12a with engineered crRNA enables amplified nucleic acid detection LT Nguyen, BM Smith, PK Jain Nature communications 11 (1), 4906, 2020 | 257 | 2020 |
A thermostable Cas12b from Brevibacillus leverages one-pot discrimination of SARS-CoV-2 variants of concern LT Nguyen, NC Macaluso, BLM Pizzano, MN Cash, J Spacek, J Karasek, ... EBioMedicine - The Lancet 77, 103926, 2022 | 47 | 2022 |
Clinical validation of engineered CRISPR/Cas12a for rapid SARS-CoV-2 detection LT Nguyen, SR Rananaware, BLM Pizzano, BT Stone, PK Jain Communications Medicine 2 (1), 7, 2022 | 39* | 2022 |
Programmable RNA detection with CRISPR-Cas12a SR Rananaware, EK Vesco, GM Shoemaker, SS Anekar, LSW Sandoval, ... Nature Communications 14, 5409, 2023 | 31 | 2023 |
Engineering highly thermostable Cas12b via de novo structural analyses for one-pot detection of nucleic acids LT Nguyen, SR Rananaware, LG Yang, NC Macaluso, JE Ocana-Ortiz, ... Cell Reports Medicine 4 (5), 101037, 2023 | 16 | 2023 |
CRISPR-ENHANCE: An enhanced nucleic acid detection platform using Cas12a LT Nguyen, J Gurijala, SR Rananaware, BLM Pizzano, BT Stone, PK Jain Methods 203, 116-124, 2022 | 16 | 2022 |
Harnessing noncanonical crRNAs to improve functionality of Cas12a orthologs LT Nguyen, NC Macaluso, NR Rakestraw, DR Carman, BLM Pizzano, ... Cell reports 43 (2), 2024 | 9* | 2024 |
Rapid SARS-CoV-2 diagnosis using disposable strips and a metal-oxide-semiconductor field-effect transistor platform CW Chiu, M Xian, JL Stephany, X Xia, CC Chiang, F Ren, CT Tsai, ... Journal of Vacuum Science & Technology B 40 (2), 2022 | 7 | 2022 |
CRISPR‐based diagnostics detects invasive insect pests PR Shashank, BM Parker, SR Rananaware, D Plotkin, C Couch, LG Yang, ... Molecular Ecology Resources 24 (1), e13881, 2024 | 4 | 2024 |
CRISPR-Enhance Lateral Flow Assay P Jain, LT Nguyen, S Rananaware | 1 | 2020 |
Efficient Genome Editing with Chimeric Oligonucleotide-Directed Editing LT Nguyen, NR Rakestraw, BLM Pizzano, CB Young, Y Huang, ... bioRxiv, 2024.07. 09.602710, 2024 | | 2024 |