Metformin-induced increases in GDF15 are important for suppressing appetite and promoting weight loss EA Day, RJ Ford, BK Smith, P Mohammadi-Shemirani, MR Morrow, ... Nature Metabolism 1 (12), 1202-1208, 2019 | 232 | 2019 |
Novel drug targets for ischemic stroke identified through Mendelian randomization analysis of the blood proteome M Chong, J Sjaarda, M Pigeyre, P Mohammadi-Shemirani, R Lali, ... Circulation 140 (10), 819-830, 2019 | 110 | 2019 |
Inhibition of ATP-citrate lyase improves NASH, liver fibrosis, and dyslipidemia MR Morrow, B Batchuluun, J Wu, E Ahmadi, JM Leroux, ... Cell Metabolism 34 (6), 919-936. e8, 2022 | 85 | 2022 |
Elevated lipoprotein (a) and risk of atrial fibrillation: an observational and mendelian randomization study P Mohammadi-Shemirani, M Chong, S Narula, N Perrot, D Conen, ... Journal of the American College of Cardiology 79 (16), 1579-1590, 2022 | 64 | 2022 |
GWAS and ExWAS of blood mitochondrial DNA copy number identifies 71 loci and highlights a potential causal role in dementia M Chong, P Mohammadi-Shemirani, N Perrot, W Nelson, R Morton, ... Elife 11, e70382, 2022 | 52 | 2022 |
Effects of lifelong testosterone exposure on health and disease using Mendelian randomization P Mohammadi-Shemirani, M Chong, M Pigeyre, RW Morton, HC Gerstein, ... Elife 9, e58914, 2020 | 47 | 2020 |
Epigenetic age and the risk of incident atrial fibrillation JD Roberts, E Vittinghoff, AT Lu, A Alonso, B Wang, CM Sitlani, ... Circulation 144 (24), 1899-1911, 2021 | 45 | 2021 |
Global assessment of Mendelian stroke genetic prevalence in 101 635 individuals from 7 ethnic groups N Grami, M Chong, R Lali, P Mohammadi-Shemirani, DE Henshall, ... Stroke 51 (4), 1290-1293, 2020 | 29 | 2020 |
Calibrated rare variant genetic risk scores for complex disease prediction using large exome sequence repositories R Lali, M Chong, A Omidi, P Mohammadi-Shemirani, A Le, E Cui, G Paré Nature Communications 12 (1), 5852, 2021 | 26 | 2021 |
Surrogate adiposity markers and mortality I Khan, M Chong, A Le, P Mohammadi-Shemirani, R Morton, C Brinza, ... JAMA Network Open 6 (9), e2334836-e2334836, 2023 | 23 | 2023 |
A Mendelian randomization-based approach to identify early and sensitive diagnostic biomarkers of disease P Mohammadi-Shemirani, J Sjaarda, HC Gerstein, DJ Treleaven, ... Clinical chemistry 65 (3), 427-436, 2019 | 20 | 2019 |
Influence of genetic ancestry on human serum proteome J Sjaarda, HC Gerstein, Z Kutalik, P Mohammadi-Shemirani, M Pigeyre, ... The American Journal of Human Genetics 106 (3), 303-314, 2020 | 17 | 2020 |
An RNA foundation model enables discovery of disease mechanisms and candidate therapeutics A Celaj, AJ Gao, TTY Lau, EM Holgersen, A Lo, V Lodaya, CB Cole, ... bioRxiv, 2023.09. 20.558508, 2023 | 13 | 2023 |
Mitochondrial DNA copy number as a marker and mediator of stroke prognosis: observational and mendelian randomization analyses MR Chong, S Narula, R Morton, C Judge, L Akhabir, N Cawte, N Pathan, ... Neurology 98 (5), e470-e482, 2022 | 13 | 2022 |
From ‘omics to multi-omics technologies: the discovery of novel causal mediators P Mohammadi-Shemirani, T Sood, G Paré Current atherosclerosis reports 25 (2), 55-65, 2023 | 10 | 2023 |
Biomarkers associated with severe COVID-19 among populations with high cardiometabolic risk: a 2-sample mendelian randomization study T Sood, N Perrot, M Chong, P Mohammadi-Shemirani, M Mushtaha, ... JAMA Network Open 6 (7), e2325914-e2325914, 2023 | 4 | 2023 |
Leveraging related health phenotypes for polygenic prediction of impulsive choice, impulsive action, and impulsive personality traits in 1534 European ancestry community adults WQ Deng, K Belisario, JC Gray, EE Levitt, P Mohammadi‐Shemirani, ... Genes, Brain and Behavior 22 (3), e12848, 2023 | 4 | 2023 |
ACLY and CKD: a Mendelian randomization analysis P Mohammadi-Shemirani, M Chong, N Perrot, M Pigeyre, GR Steinberg, ... Kidney International Reports 7 (7), 1673-1681, 2022 | 2 | 2022 |
An RNA foundation model enables discovery of disease mechanisms and candidate therapeutics B Frey, A Celaj, A Gao, T Lau, E Holgersen, A Lo, V Lodaya, C Cole, ... | 1 | 2023 |
Lipoprotein (a) Cholesterol Masquerading as Low-Density Lipoprotein Cholesterol: Catch Me if You Can G Paré, M Chong, P Mohammadi-Shemirani Journal of the American College of Cardiology 79 (11), 1047-1049, 2022 | 1 | 2022 |