Mitochondria and neuronal activity O Kann, R Kovács American Journal of Physiology-Cell Physiology 292 (2), C641-C657, 2007 | 928 | 2007 |
Brain energy rescue: an emerging therapeutic concept for neurodegenerative disorders of ageing SC Cunnane, E Trushina, C Morland, A Prigione, G Casadesus, ... Nature reviews Drug discovery 19 (9), 609-633, 2020 | 581 | 2020 |
Elevation of basal intracellular calcium as a central element in the activation of brain macrophages (microglia): suppression of receptor-evoked calcium signaling and control … A Hoffmann, O Kann, C Ohlemeyer, UK Hanisch, H Kettenmann Journal of Neuroscience 23 (11), 4410-4419, 2003 | 316 | 2003 |
Highly energized inhibitory interneurons are a central element for information processing in cortical networks O Kann, IE Papageorgiou, A Draguhn Journal of Cerebral Blood Flow & Metabolism 34 (8), 1270-1282, 2014 | 262 | 2014 |
The interneuron energy hypothesis: implications for brain disease O Kann Neurobiology of disease 90, 75-85, 2016 | 249 | 2016 |
Gamma oscillations in the hippocampus require high complex I gene expression and strong functional performance of mitochondria O Kann, C Huchzermeyer, R Kovacs, S Wirtz, M Schuelke Brain 134 (2), 345-358, 2011 | 197 | 2011 |
TLR4-activated microglia require IFN-γ to induce severe neuronal dysfunction and death in situ IE Papageorgiou, A Lewen, LV Galow, T Cesetti, J Scheffel, T Regen, ... Proceedings of the National Academy of Sciences 113 (1), 212-217, 2016 | 195 | 2016 |
Free radical–mediated cell damage after experimental status epilepticus in hippocampal slice cultures R Kovács, S Schuchmann, S Gabriel, O Kann, J Kardos, U Heinemann Journal of neurophysiology 88 (6), 2909-2918, 2002 | 179 | 2002 |
Brain endothelial-and epithelial-specific interferon receptor chain 1 drives virus-induced sickness behavior and cognitive impairment T Blank, CN Detje, A Spieß, N Hagemeyer, SM Brendecke, J Wolfart, ... Immunity 44 (4), 901-912, 2016 | 175 | 2016 |
ERK activation causes epilepsy by stimulating NMDA receptor activity AS Nateri, G Raivich, C Gebhardt, C Da Costa, H Naumann, ... The EMBO journal 26 (23), 4891-4901, 2007 | 168 | 2007 |
Metabolic dysfunction during neuronal activation in the ex vivo hippocampus from chronic epileptic rats and humans O Kann, R Kovács, M Njunting, CJ Behrens, J Otáhal, TN Lehmann, ... Brain 128 (10), 2396-2407, 2005 | 162 | 2005 |
Activation of mouse microglial cells affects P2 receptor signaling T Möller, O Kann, A Verkhratsky, H Kettenmann Brain research 853 (1), 49-59, 2000 | 144 | 2000 |
Gamma oscillations and spontaneous network activity in the hippocampus are highly sensitive to decreases in pO2 and concomitant changes in mitochondrial redox state C Huchzermeyer, K Albus, HJ Gabriel, J Otáhal, N Taubenberger, ... Journal of Neuroscience 28 (5), 1153-1162, 2008 | 128 | 2008 |
Microglial activation by components of gram-positive and-negative bacteria: distinct and common routes to the induction of ion channels and cytokines M Prinz, O Kann, HJ Draheim, RR Schumann, H Kettenmann, JR Weber, ... Journal of neuropathology and experimental neurology 58 (10), 1078-1089, 1999 | 126 | 1999 |
Endogenous nitric oxide is a key promoting factor for initiation of seizure-like events in hippocampal and entorhinal cortex slices R Kovács, A Rabanus, J Otáhal, A Patzak, J Kardos, K Albus, ... Journal of Neuroscience 29 (26), 8565-8577, 2009 | 118 | 2009 |
Coupling of neuronal activity and mitochondrial metabolism as revealed by NAD (P) H fluorescence signals in organotypic hippocampal slice cultures of the rat O Kann, S Schuchmann, K Buchheim, U Heinemann Neuroscience 119 (1), 87-100, 2003 | 116 | 2003 |
Mitochondrial calcium ion and membrane potential transients follow the pattern of epileptiform discharges in hippocampal slice cultures R Kovács, J Kardos, U Heinemann, O Kann Journal of Neuroscience 25 (17), 4260-4269, 2005 | 114 | 2005 |
Complex III-dependent superoxide production of brain mitochondria contributes to seizure-related ROS formation D Malinska, B Kulawiak, AP Kudin, R Kovacs, C Huchzermeyer, O Kann, ... Biochimica et Biophysica Acta (BBA)-Bioenergetics 1797 (6-7), 1163-1170, 2010 | 113 | 2010 |
The protein tyrosine kinase inhibitor AG126 prevents the massive microglial cytokine induction by pneumococcal cell walls UK Hanisch, M Prinz, K Angstwurm, KG Häusler, O Kann, H Kettenmann, ... European journal of immunology 31 (7), 2104-2115, 2001 | 104 | 2001 |
Priming of microglia with IFN-γ slows neuronal gamma oscillations in situ TT Ta, HO Dikmen, S Schilling, B Chausse, A Lewen, JO Hollnagel, ... Proceedings of the National Academy of Sciences 116 (10), 4637-4642, 2019 | 101 | 2019 |