NK cell responses to cytomegalovirus infection lead to stable imprints in the human KIR repertoire and involve activating KIRs V Béziat, LL Liu, JA Malmberg, MA Ivarsson, E Sohlberg, AT Björklund, ... Blood, The Journal of the American Society of Hematology 121 (14), 2678-2688, 2013 | 542 | 2013 |
Extent and distribution of linkage disequilibrium in three genomic regions GR Abecasis, E Noguchi, A Heinzmann, JA Traherne, S Bhattacharyya, ... The American Journal of Human Genetics 68 (1), 191-197, 2001 | 457 | 2001 |
Variation analysis and gene annotation of eight MHC haplotypes: the MHC Haplotype Project R Horton, R Gibson, P Coggill, M Miretti, RJ Allcock, J Almeida, S Forbes, ... Immunogenetics 60, 1-18, 2008 | 386 | 2008 |
High-density mapping of the MHC identifies a shared role for HLA-DRB1* 01: 03 in inflammatory bowel diseases and heterozygous advantage in ulcerative colitis P Goyette, G Boucher, D Mallon, E Ellinghaus, L Jostins, H Huang, ... Nature genetics 47 (2), 172-179, 2015 | 344 | 2015 |
Human MHC architecture and evolution: implications for disease association studies JA Traherne International journal of immunogenetics 35 (3), 179-192, 2008 | 285 | 2008 |
Genome-wide association study identifies distinct genetic contributions to prognosis and susceptibility in Crohn's disease JC Lee, D Biasci, R Roberts, RB Gearry, JC Mansfield, T Ahmad, ... Nature genetics 49 (2), 262-268, 2017 | 269 | 2017 |
A second major histocompatibility complex susceptibility locus for multiple sclerosis TW Yeo, PL De Jager, SG Gregory, LF Barcellos, A Walton, A Goris, ... Annals of Neurology: Official Journal of the American Neurological …, 2007 | 242 | 2007 |
Critical role of CD2 co-stimulation in adaptive natural killer cell responses revealed in NKG2C-deficient humans LL Liu, J Landskron, EH Ask, M Enqvist, E Sohlberg, JA Traherne, ... Cell reports 15 (5), 1088-1099, 2016 | 236 | 2016 |
Copy number variation leads to considerable diversity for B but not A haplotypes of the human KIR genes encoding NK cell receptors W Jiang, C Johnson, J Jayaraman, N Simecek, J Noble, MF Moffatt, ... Genome research 22 (10), 1845-1854, 2012 | 205 | 2012 |
Genetic analysis of completely sequenced disease-associated MHC haplotypes identifies shuffling of segments in recent human history JA Traherne, R Horton, AN Roberts, MM Miretti, ME Hurles, CA Stewart, ... PLoS genetics 2 (1), e9, 2006 | 186 | 2006 |
A KIR B centromeric region present in Africans but not Europeans protects pregnant women from pre-eclampsia A Nakimuli, O Chazara, SE Hiby, L Farrell, S Tukwasibwe, J Jayaraman, ... Proceedings of the National Academy of Sciences 112 (3), 845-850, 2015 | 166 | 2015 |
Cutting edge: expansion of the KIR locus by unequal crossing over MP Martin, A Bashirova, J Traherne, J Trowsdale, M Carrington The Journal of Immunology 171 (5), 2192-2195, 2003 | 166 | 2003 |
ULBP6/RAET1L is an additional human NKG2D ligand RA Eagle, JA Traherne, JR Hair, I Jafferji, J Trowsdale European journal of immunology 39 (11), 3207-3216, 2009 | 148 | 2009 |
Defining KIR and HLA class I genotypes at highest resolution via high-throughput sequencing PJ Norman, JA Hollenbach, N Nemat-Gorgani, WM Marin, SJ Norberg, ... The American Journal of Human Genetics 99 (2), 375-391, 2016 | 144 | 2016 |
Regulation of NKG2D ligand gene expression RA Eagle, JA Traherne, O Ashiru, MR Wills, J Trowsdale Human immunology 67 (3), 159-169, 2006 | 136 | 2006 |
SIGLEC16 encodes a DAP12‐associated receptor expressed in macrophages that evolved from its inhibitory counterpart SIGLEC11 and has functional and non … H Cao, U Lakner, B de Bono, JA Traherne, J Trowsdale, AD Barrow European journal of immunology 38 (8), 2303-2315, 2008 | 129 | 2008 |
Mechanisms of copy number variation and hybrid gene formation in the KIR immune gene complex JA Traherne, M Martin, R Ward, M Ohashi, F Pellett, D Gladman, ... Human molecular genetics 19 (5), 737-751, 2010 | 122 | 2010 |
Influence of KIR gene copy number on natural killer cell education V Béziat, JA Traherne, LL Liu, J Jayaraman, M Enqvist, S Larsson, ... Blood, The Journal of the American Society of Hematology 121 (23), 4703-4707, 2013 | 95 | 2013 |
Deciphering the killer‐cell immunoglobulin‐like receptor system at super‐resolution for natural killer and T‐cell biology V Béziat, HG Hilton, PJ Norman, JA Traherne Immunology 150 (3), 248-264, 2017 | 91 | 2017 |
Imputation of KIR types from SNP variation data D Vukcevic, JA Traherne, S Næss, E Ellinghaus, Y Kamatani, A Dilthey, ... The American Journal of Human Genetics 97 (4), 593-607, 2015 | 74 | 2015 |