Longitudinal molecular trajectories of diffuse glioma in adults FP Barthel, KC Johnson, FS Varn, AD Moskalik, G Tanner, E Kocakavuk, ... Nature 576 (7785), 112-120, 2019 | 475 | 2019 |
Intravenous delivery of oncolytic reovirus to brain tumor patients immunologically primes for subsequent checkpoint blockade A Samson, KJ Scott, D Taggart, EJ West, E Wilson, GJ Nuovo, S Thomson, ... Science translational medicine 10 (422), eaam7577, 2018 | 398 | 2018 |
Genomic Subtypes of Non-invasive Bladder Cancer with Distinct Metabolic Profile and Female Gender Bias in KDM6A Mutation Frequency CD Hurst, O Alder, FM Platt, A Droop, LF Stead, JE Burns, GJ Burghel, ... Cancer cell 32 (5), 701-715. e7, 2017 | 300 | 2017 |
Genomic Subtypes of Non-invasive Bladder Cancer with Distinct Metabolic Profile and Female Gender Bias in KDM6A Mutation Frequency CD Hurst, O Alder, FM Platt, A Droop, LF Stead, JE Burns, GJ Burghel, ... Cancer Cell 32 (5), 701-715. e7, 2017 | 300 | 2017 |
Glioma through the looking GLASS: molecular evolution of diffuse gliomas and the Glioma Longitudinal Analysis Consortium Neuro-oncology 20 (7), 873-884, 2018 | 146 | 2018 |
RAD51 Is a Selective DNA Repair Target to Radiosensitize Glioma Stem Cells HO King, T Brend, HL Payne, A Wright, TA Ward, K Patel, T Egnuni, ... Stem Cell Reports 8 (1), 125-139, 2017 | 144 | 2017 |
Expression profiling of single cells and patient cohorts identifies multiple immunosuppressive pathways and an altered NK cell phenotype in glioblastoma HJ Close, LF Stead, J Nsengimana, KA Reilly, A Droop, H Wurdak, ... Clinical & Experimental Immunology, 2019 | 70 | 2019 |
Accurately Identifying Low‐Allelic Fraction Variants in Single Samples with Next‐Generation Sequencing: Applications in Tumor Subclone Resolution LF Stead, KM Sutton, GR Taylor, P Quirke, P Rabbitts Human mutation 34 (10), 1432-1438, 2013 | 66 | 2013 |
Exploring the surfaceome of Ewing sarcoma identifies a new and unique therapeutic target J Town, H Pais, S Harrison, LF Stead, C Bataille, W Bunjobpol, J Zhang, ... Proceedings of the National Academy of Sciences, 201521251, 2016 | 61 | 2016 |
Elucidating drivers of oral epithelial dysplasia formation and malignant transformation to cancer using RNAseq C Conway, JL Graham, P Chengot, C Daly, R Chalkley, L Ross, A Droop, ... Oncotarget 6 (37), 40186, 2015 | 45 | 2015 |
Functional and developmental expression of a zebrafish Kir1. 1 (ROMK) potassium channel homologue Kcnj1 L Abbas, S Hajihashemi, LF Stead, GJ Cooper, TL Ware, TS Munsey, ... The Journal of Physiology 589 (6), 1489-1503, 2011 | 43 | 2011 |
The clonal relationships between pre‐cancer and cancer revealed by ultra‐deep sequencing HM Wood, C Conway, C Daly, R Chalkley, S Berri, B Senguven, L Stead, ... The Journal of pathology 237 (3), 296-306, 2015 | 37 | 2015 |
Down-Regulation of miR-92 in Breast Epithelial Cells and in Normal but Not Tumour Fibroblasts Contributes to Breast Carcinogenesis L Smith, EW Baxter, PA Chambers, CA Green, AM Hanby, TA Hughes, ... PloS one 10 (10), e0139698, 2015 | 31 | 2015 |
KvSNP: accurately predicting the effect of genetic variants in voltage-gated potassium channels LF Stead, IC Wood, DR Westhead Bioinformatics 27 (16), 2181-2186, 2011 | 31 | 2011 |
A novel genomic signature reclassifies an oral cancer subtype M Samman, HM Wood, C Conway, L Stead, C Daly, R Chalkley, S Berri, ... International Journal of Cancer 137 (10), 2364-2373, 2015 | 24 | 2015 |
A Case-Matched Gender Comparison Transcriptomic Screen Identifies eIF4E and eIF5 as Potential Prognostic Markers in Male Breast Cancer MP Humphries, SS Rajan, A Droop, CAB Suleman, C Carbone, C Nilsson, ... Clinical Cancer Research 23 (10), 2575-2583, 2017 | 20 | 2017 |
The transcriptional consequences of somatic amplifications, deletions, and rearrangements in a human lung squamous cell carcinoma LF Stead, S Berri, HM Wood, P Egan, C Conway, C Daly, ... Neoplasia 14 (11), 1075-IN16, 2012 | 20 | 2012 |
Genomic and expression analyses define MUC17 and PCNX1 as predictors of chemotherapy response in breast cancer WS Al Amri, LM Allinson, DE Baxter, SM Bell, AM Hanby, SJ Jones, ... Molecular Cancer Therapeutics, 2019 | 19 | 2019 |
Doomed from the TERT? A Two-Stage Model of Tumorigenesis in IDH-Wild-Type Glioblastoma LF Stead, RGW Verhaak Cancer cell 35 (4), 542-544, 2019 | 14 | 2019 |
Upregulated WEE1 protects endothelial cells of colorectal cancer liver metastases. PJ Webster, AT Littlejohns, HJ Gaunt, RS Young, B Rode, JE Ritchie, ... Oncotarget, 2017 | 12 | 2017 |