Inteins: nature's gift to protein chemists NH Shah, TW Muir Chemical Science 5 (2), 446-461, 2014 | 437 | 2014 |
Oligo (N-aryl glycines): a new twist on structured peptoids NH Shah, GL Butterfoss, K Nguyen, B Yoo, R Bonneau, DL Rabenstein, ... Journal of the American Chemical Society 130 (49), 16622-16632, 2008 | 212 | 2008 |
Ultrafast protein splicing is common among cyanobacterial split inteins: implications for protein engineering NH Shah, GP Dann, M Vila-Perelló, Z Liu, TW Muir Journal of the American Chemical Society 134 (28), 11338-11341, 2012 | 172 | 2012 |
Lck promotes Zap70-dependent LAT phosphorylation by bridging Zap70 to LAT WL Lo, NH Shah, N Ahsan, V Horkova, O Stepanek, AR Salomon, ... Nature immunology 19 (7), 733-741, 2018 | 155 | 2018 |
Design of a Split Intein with Exceptional Protein Splicing Activity AJ Stevens, ZZ Brown, NH Shah, G Sekar, D Cowburn, TW Muir Journal of the American Chemical Society 138 (7), 2162-2165, 2016 | 155 | 2016 |
ZAP-70 in signaling, biology, and disease BB Au-Yeung, NH Shah, L Shen, A Weiss Annual review of immunology 36 (1), 127-156, 2018 | 139 | 2018 |
A promiscuous split intein with expanded protein engineering applications AJ Stevens, G Sekar, NH Shah, AZ Mostafavi, D Cowburn, TW Muir Proceedings of the National Academy of Sciences 114 (32), 8538-8543, 2017 | 128 | 2017 |
Deconstruction of the Ras switching cycle through saturation mutagenesis P Bandaru, NH Shah, M Bhattacharyya, JP Barton, Y Kondo, JC Cofsky, ... eLife 6, e27810, 2017 | 117 | 2017 |
Streamlined expressed protein ligation using split inteins M Vila-Perelló, Z Liu, NH Shah, JA Willis, J Idoyaga, TW Muir Journal of the American Chemical Society 135 (1), 286-292, 2013 | 108 | 2013 |
An electrostatic selection mechanism controls sequential kinase signaling downstream of the T cell receptor NH Shah, Q Wang, Q Yan, D Karandur, TA Kadlecek, IR Fallahee, ... Elife 5, e20105, 2016 | 96 | 2016 |
Naturally split inteins assemble through a “capture and collapse” mechanism NH Shah, E Eryilmaz, D Cowburn, TW Muir Journal of the American Chemical Society 135 (49), 18673-18681, 2013 | 94 | 2013 |
Kinetic control of one-pot trans-splicing reactions by using a wild-type and designed split intein NH Shah, M Vila-Perelló, TW Muir Angewandte Chemie (International ed. in English) 50 (29), 6511, 2011 | 90 | 2011 |
Extein residues play an intimate role in the rate-limiting step of protein trans-splicing NH Shah, E Eryilmaz, D Cowburn, TW Muir Journal of the American Chemical Society 135 (15), 5839-5847, 2013 | 88 | 2013 |
Structural and dynamical features of inteins and implications on protein splicing E Eryilmaz, NH Shah, TW Muir, D Cowburn Journal of Biological Chemistry 289 (21), 14506-14511, 2014 | 85 | 2014 |
Slow phosphorylation of a tyrosine residue in LAT optimizes T cell ligand discrimination WL Lo, NH Shah, SA Rubin, W Zhang, V Horkova, IR Fallahee, ... Nature immunology 20 (11), 1481-1493, 2019 | 79 | 2019 |
The Src module: an ancient scaffold in the evolution of cytoplasmic tyrosine kinases NH Shah, JF Amacher, LM Nocka, J Kuriyan Critical Reviews in Biochemistry and Molecular Biology, 2018 | 69 | 2018 |
Peptoid atropisomers B Paul, GL Butterfoss, MG Boswell, PD Renfrew, FG Yeung, NH Shah, ... Journal of the American Chemical Society 133 (28), 10910-10919, 2011 | 69 | 2011 |
Prediction of protein–ligand binding affinity from sequencing data with interpretable machine learning HT Rube, C Rastogi, S Feng, JF Kribelbauer, A Li, B Becerra, LAN Melo, ... Nature Biotechnology 40 (10), 1520-1527, 2022 | 67 | 2022 |
SPLIT INTEINS, CONJUGATES AND USES THEREOF TW Muir, M Vila-perello, Z Liu, NH Shah US Patent 20,150,344,549, 2015 | 66 | 2015 |
Fine-tuning of substrate preferences of the Src-family kinase Lck revealed through a high-throughput specificity screen NH Shah, M Löbel, A Weiss, J Kuriyan eLife 7, e35190, 2018 | 60 | 2018 |