Alzheimer's disease in Down syndrome: neurobiology and risk WB Zigman, IT Lott Mental retardation and developmental disabilities research reviews 13 (3 …, 2007 | 395 | 2007 |
Atypical aging in Down syndrome WB Zigman Developmental disabilities research reviews 18 (1), 51-67, 2013 | 326 | 2013 |
Prevalence of chronic medical conditions in adults with mental retardation: comparison with the general population D Kapell, B Nightingale, A Rodriguez, JH Lee, WB Zigman, N Schupf Mental retardation 36 (4), 269-279, 1998 | 250 | 1998 |
Prevalence of dementia in adults with and without Down syndrome. WB Zigman, N Schupf, E Sersen, W Silverman American journal of mental retardation: AJMR 100 (4), 403-412, 1996 | 211 | 1996 |
Incidence and prevalence of dementia in elderly adults with mental retardation without Down syndrome WB Zigman, N Schupf, DA Devenny, C Miezejeski, R Ryan, TK Urv, ... American journal on mental retardation 109 (2), 126-141, 2004 | 183 | 2004 |
Elevated plasma amyloid β-peptide 1–42 and onset of dementia in adults with Down syndrome N Schupf, B Patel, W Silverman, WB Zigman, N Zhong, B Tycko, ... Neuroscience letters 301 (3), 199-203, 2001 | 170 | 2001 |
Early menopause in women with Down's syndrome N Schupf, W Zigman, D Kapell, JH Lee, J Kline, B Levin Journal of Intellectual Disability Research 41 (3), 264-267, 1997 | 153 | 1997 |
Premature regression of adults with Down syndrome. WB Zigman, N Schupf, RA Lubin, WP Silverman American Journal of Mental Deficiency 92 (2), 161-168, 1987 | 148 | 1987 |
Alzheimer's disease in adults with Down syndrome WB Zigman, DA Devenny, SJ KrinskyMcHale, EC Jenkins, TK Urv, ... International review of research in mental retardation 36, 103-145, 2008 | 140 | 2008 |
Altered DNA methylation in leukocytes with trisomy 21 K Kerkel, N Schupf, K Hatta, D Pang, M Salas, A Kratz, M Minden, V Murty, ... PLoS genetics 6 (11), e1001212, 2010 | 137 | 2010 |
Onset of dementia is associated with apolipoprotein E ε4 in Down's syndrome N Schupf, JH Lee, D Kapell, W Zigman, B Canto, B Tycko, R Mayeux Annals of Neurology: Official Journal of the American Neurological …, 1996 | 125 | 1996 |
Cell type-specific over-expression of chromosome 21 genes in fibroblasts and fetal hearts with trisomy 21 CM Li, M Guo, M Salas, N Schupf, W Silverman, WB Zigman, S Husain, ... BMC medical genetics 7, 1-15, 2006 | 110 | 2006 |
Elevated plasma β-amyloid peptide Aβ42 levels, incident dementia, and mortality in Down syndrome N Schupf, B Patel, D Pang, WB Zigman, W Silverman, PD Mehta, ... Archives of neurology 64 (7), 1007-1013, 2007 | 105 | 2007 |
Change in plasma Aβ peptides and onset of dementia in adults with Down syndrome N Schupf, WB Zigman, MX Tang, D Pang, R Mayeux, P Mehta, ... Neurology 75 (18), 1639-1644, 2010 | 102 | 2010 |
Significant effect of APOE epsilon 4 genotype on the risk of dementia in Alzheimer's disease and mortality in persons with Down syndrome VP Prasher, SG Sajith, SD Rees, A Patel, S Tewari, N Schupf, WB Zigman International Journal of Geriatric Psychiatry: A journal of the psychiatry …, 2008 | 99 | 2008 |
The epidemiology of Alzheimer disease in intellectual disability: results and recommendations from an international conference W Zigman, N Schupf, M Haveman, W Silverman Journal of Intellectual Disability Research 41 (1), 76-80, 1997 | 99 | 1997 |
Telomere shortening in T lymphocytes of older individuals with Down syndrome and dementia EC Jenkins, MT Velinov, L Ye, H Gu, S Li, EC Jenkins Jr, SS Brooks, ... Neurobiology of aging 27 (7), 941-945, 2006 | 95 | 2006 |
Dementia in adults with mental retardation: assessment at a single point in time W Silverman, N Schupf, W Zigman, D Devenny, C Miezejeski, R Schubert, ... American Journal on Mental Retardation 109 (2), 111-125, 2004 | 93 | 2004 |
Incidence and temporal patterns of adaptive behavior change in adults with mental retardation WB Zigman, N Schupf, T Urv, A Zigman, W Silverman American Journal on Mental Retardation 107 (3), 161-174, 2002 | 92 | 2002 |
Neuropathological diagnosis of Alzheimer disease. HM Wisniewski, A Robe, W Zigman, W Silverman Journal of neuropathology and experimental neurology 48 (6), 606-609, 1989 | 91 | 1989 |