Risks of breast, ovarian, and contralateral breast cancer for BRCA1 and BRCA2 mutation carriers KB Kuchenbaecker, JL Hopper, DR Barnes, KA Phillips, TM Mooij, ... Jama 317 (23), 2402-2416, 2017 | 2867 | 2017 |
The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis Interleukin-6 Receptor Mendelian Randomisation Analysis (IL6R MR) Consortium The Lancet 379 (9822), 1214-1224, 2012 | 1092 | 2012 |
Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data MV Holmes, CE Dale, L Zuccolo, RJ Silverwood, Y Guo, Z Ye, ... Bmj 349, g4164, 2014 | 833 | 2014 |
HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: evidence from genetic analysis and randomised trials DI Swerdlow, D Preiss, KB Kuchenbaecker, MV Holmes, JEL Engmann, ... The Lancet 385 (9965), 351-361, 2015 | 752 | 2015 |
Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer SE Bojesen, KA Pooley, SE Johnatty, J Beesley, K Michailidou, JP Tyrer, ... Nature genetics 45 (4), 371-384, 2013 | 654 | 2013 |
Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure S Shah, A Henry, C Roselli, H Lin, G Sveinbjörnsson, G Fatemifar, ... Nature communications 11 (1), 163, 2020 | 590 | 2020 |
Genome-wide association studies in ancestrally diverse populations: opportunities, methods, pitfalls, and recommendations RE Peterson, K Kuchenbaecker, RK Walters, CY Chen, AB Popejoy, ... Cell 179 (3), 589-603, 2019 | 558 | 2019 |
Identification of 12 new susceptibility loci for different histotypes of epithelial ovarian cancer CM Phelan, KB Kuchenbaecker, JP Tyrer, SP Kar, K Lawrenson, ... Nature genetics 49 (5), 680-691, 2017 | 427 | 2017 |
Identification of ten variants associated with risk of estrogen-receptor-negative breast cancer RL Milne, KB Kuchenbaecker, K Michailidou, J Beesley, S Kar, ... Nature genetics 49 (12), 1767-1778, 2017 | 377 | 2017 |
The OncoArray Consortium: a network for understanding the genetic architecture of common cancers CI Amos, J Dennis, Z Wang, J Byun, FR Schumacher, SA Gayther, ... Cancer epidemiology, biomarkers & prevention 26 (1), 126-135, 2017 | 370 | 2017 |
Evaluation of Polygenic Risk Scores for Breast and Ovarian Cancer Risk Prediction in BRCA1 and BRCA2 Mutation Carriers KB Kuchenbaecker, L McGuffog, D Barrowdale, A Lee, P Soucy, J Dennis, ... JNCI: Journal of the National Cancer Institute 109 (7), djw302, 2017 | 333 | 2017 |
Genome-Wide Association Study in BRCA1 Mutation Carriers Identifies Novel Loci Associated with Breast and Ovarian Cancer Risk FJ Couch, X Wang, L McGuffog, A Lee, C Olswold, KB Kuchenbaecker, ... PLoS genetics 9 (3), e1003212, 2013 | 333 | 2013 |
Selecting instruments for Mendelian randomization in the wake of genome-wide association studies DI Swerdlow, KB Kuchenbaecker, S Shah, R Sofat, MV Holmes, J White, ... International journal of epidemiology 45 (5), 1600-1616, 2016 | 316 | 2016 |
Identification of six new susceptibility loci for invasive epithelial ovarian cancer KB Kuchenbaecker, SJ Ramus, J Tyrer, A Lee, HC Shen, J Beesley, ... Nature genetics 47 (2), 164-171, 2015 | 313 | 2015 |
A roadmap to increase diversity in genomic studies S Fatumo, T Chikowore, A Choudhury, M Ayub, AR Martin, ... Nature medicine 28 (2), 243-250, 2022 | 290 | 2022 |
BOADICEA breast cancer risk prediction model: updates to cancer incidences, tumour pathology and web interface AJ Lee, AP Cunningham, KB Kuchenbaecker, N Mavaddat, DF Easton, ... British journal of cancer 110 (2), 535-545, 2014 | 252 | 2014 |
Prediction of Breast and Prostate Cancer Risks in Male BRCA1 and BRCA2 Mutation Carriers Using Polygenic Risk Scores J Lecarpentier, V Silvestri, KB Kuchenbaecker, D Barrowdale, J Dennis, ... Journal of Clinical Oncology 35 (20), 2240-2250, 2017 | 191 | 2017 |
Breast cancer risk variants at 6q25 display different phenotype associations and regulate ESR1, RMND1 and CCDC170 AM Dunning, K Michailidou, KB Kuchenbaecker, D Thompson, JD French, ... Nature genetics 48 (4), 374-386, 2016 | 160 | 2016 |
Identification of a BRCA2-Specific Modifier Locus at 6p24 Related to Breast Cancer Risk MM Gaudet, KB Kuchenbaecker, J Vijai, RJ Klein, T Kirchhoff, L McGuffog, ... PLoS genetics 9 (3), e1003173, 2013 | 154 | 2013 |
Identification of four novel susceptibility loci for oestrogen receptor negative breast cancer FJ Couch, KB Kuchenbaecker, K Michailidou, GA Mendoza-Fandino, ... Nature communications 7 (1), 11375, 2016 | 134 | 2016 |