Dual domain recognition determines SARS-CoV-2 PLpro selectivity for human ISG15 and K48-linked di-ubiquitin PM Wydorski, J Osipiuk, BT Lanham, C Tesar, M Endres, E Engle, ... Nature communications 14 (1), 2366, 2023 | 24* | 2023 |
Seed-competent tau monomer initiates pathology in a tauopathy mouse model H Mirbaha, D Chen, V Mullapudi, SJ Terpack, CL White, LA Joachimiak, ... Journal of Biological Chemistry 298 (8), 2022 | 22 | 2022 |
Network of hotspot interactions cluster tau amyloid folds V Mullapudi, J Vaquer-Alicea, V Bommareddy, AR Vega, BD Ryder, ... Nature communications 14 (1), 895, 2023 | 13 | 2023 |
FTD-tau S320F mutation stabilizes local structure and allosterically promotes amyloid motif-dependent aggregation D Chen, S Bali, R Singh, A Wosztyl, V Mullapudi, J Vaquer-Alicea, ... Nature communications 14 (1), 1625, 2023 | 7 | 2023 |
DnaJC7 specifically regulates tau seeding VA Perez, DW Sanders, A Mendoza-Oliva, BE Stopschinski, V Mullapudi, ... Elife 12, e86936, 2023 | 6 | 2023 |
Disease-associated patterns of acetylation stabilize tau fibril formation L Li, BA Nguyen, V Mullapudi, Y Li, L Saelices, LA Joachimiak Structure 31 (9), 1025-1037. e4, 2023 | 5 | 2023 |
Development of a new DHFR-based destabilizing domain with enhanced basal turnover and applicability in mammalian systems E Nakahara, V Mullapudi, GE Collier, LA Joachimiak, JD Hulleman ACS chemical biology 17 (10), 2877-2889, 2022 | 2 | 2022 |