Amiodarone has intrinsic anti-Trypanosoma cruzi activity and acts synergistically with posaconazole G Benaim, JM Sanders, Y Garcia-Marchán, C Colina, R Lira, AR Caldera, ... Journal of medicinal chemistry 49 (3), 892-899, 2006 | 251 | 2006 |
Child day care risks of common infectious diseases revisited N Lu, ME Samuels, L Shi, SL Baker, SH Glover, JM Sanders Child: care, health and development 30 (4), 361-368, 2004 | 189 | 2004 |
Quantitative structure− activity relationships for γδ T cell activation by bisphosphonates JM Sanders, S Ghosh, JMW Chan, G Meints, H Wang, AM Raker, Y Song, ... Journal of medicinal chemistry 47 (2), 375-384, 2004 | 173 | 2004 |
Activity of bisphosphonates against Trypanosoma brucei rhodesiense MB Martin, JM Sanders, H Kendrick, K de Luca-Fradley, JC Lewis, ... Journal of medicinal chemistry 45 (14), 2904-2914, 2002 | 149 | 2002 |
3-D QSAR investigations of the inhibition of Leishmania major farnesyl pyrophosphate synthase by bisphosphonates JM Sanders, AO Gómez, J Mao, GA Meints, EM Van Brussel, A Burzynska, ... Journal of medicinal chemistry 46 (24), 5171-5183, 2003 | 146 | 2003 |
Discovery of a 3-(4-pyrimidinyl) indazole (MLi-2), an orally available and selective leucine-rich repeat kinase 2 (LRRK2) inhibitor that reduces brain kinase activity JD Scott, DE DeMong, TJ Greshock, K Basu, X Dai, J Harris, A Hruza, ... Journal of medicinal chemistry 60 (7), 2983-2992, 2017 | 128 | 2017 |
Inhibition of geranylgeranyl diphosphate synthase by bisphosphonates and diphosphates: a potential route to new bone antiresorption and antiparasitic agents CM Szabo, Y Matsumura, S Fukura, MB Martin, JM Sanders, S Sengupta, ... Journal of medicinal chemistry 45 (11), 2185-2196, 2002 | 125 | 2002 |
Farnesyl pyrophosphate synthase is an essential enzyme in Trypanosoma bruce in vitro RNA interference and in vivo inhibition studies A Montalvetti, A Fernandez, JM Sanders, S Ghosh, E Van Brussel, ... Journal of Biological Chemistry 278 (19), 17075-17083, 2003 | 116 | 2003 |
Solid-state NMR, crystallographic, and computational investigation of bisphosphonates and farnesyl diphosphate synthase− bisphosphonate complexes J Mao, S Mukherjee, Y Zhang, R Cao, JM Sanders, Y Song, Y Zhang, ... Journal of the American Chemical Society 128 (45), 14485-14497, 2006 | 109 | 2006 |
Pyridinium-1-yl bisphosphonates are potent inhibitors of farnesyl diphosphate synthase and bone resorption JM Sanders, Y Song, JMW Chan, Y Zhang, S Jennings, T Kosztowski, ... Journal of medicinal chemistry 48 (8), 2957-2963, 2005 | 106 | 2005 |
Crystallographic structures of two bisphosphonate: 1-deoxyxylulose-5-phosphate reductoisomerase complexes S Yajima, K Hara, JM Sanders, F Yin, K Ohsawa, J Wiesner, H Jomaa, ... Journal of the American Chemical Society 126 (35), 10824-10825, 2004 | 102 | 2004 |
Maximizing diversity from a kinase screen: identification of novel and selective pan-Trk inhibitors for chronic pain SJ Stachel, JM Sanders, DA Henze, MT Rudd, HP Su, Y Li, KK Nanda, ... Journal of Medicinal Chemistry 57 (13), 5800-5816, 2014 | 77 | 2014 |
EphA4 rtk inhibitors for treatment of neurological and neurodegenerative disorders and cancer HA Rajapakse, KP Moore, PG Nantermet, JM Sanders, ... US Patent App. 12/473,773, 2010 | 73 | 2010 |
Measurements of multiple molecules using a CryoArray RA Star, T Miyaji, SM Hewitt, LA Liotta US Patent 6,951,761, 2005 | 59 | 2005 |
Epha4 rtk inhibitors for treatment of neurological and neurodegenerative disorders and cancer PG Nantermet, HA Rajapakse, T Sagara, JM Sanders, H Zhu US Patent App. 12/473,810, 2010 | 53 | 2010 |
Leucine-rich repeat kinase 2 (LRRK2) cellular biology: a review of recent advances in identifying physiological substrates and cellular functions RE Drolet, JM Sanders, JT Kern Journal of neurogenetics 25 (4), 140-151, 2011 | 49 | 2011 |
3-Aryl-5-phenoxymethyl-1, 3-oxazolidin-2-ones as positive allosteric modulators of mGluR2 for the treatment of schizophrenia: Hit-to-lead efforts EJ Brnardic, ME Fraley, RM Garbaccio, ME Layton, JM Sanders, ... Bioorganic & medicinal chemistry letters 20 (10), 3129-3133, 2010 | 49 | 2010 |
Structural characterization of non-active site, TrkA selective kinase inhibitors H Su, K Rickert, K Narayan, C Burlein, M Bukhtiyarova, D Hurzy, C Stump, ... PROTEIN SCIENCE 25, 161-162, 2016 | 48 | 2016 |
Synthesis and evaluation of heterocyclic catechol mimics as inhibitors of catechol-O-methyltransferase (COMT) ST Harrison, MS Poslusney, JJ Mulhearn, Z Zhao, NR Kett, JW Schubert, ... ACS medicinal chemistry letters 6 (3), 318-323, 2015 | 41 | 2015 |
Correction to Discovery of 2-Pyridinone Aminals: A Prodrug Strategy to Advance a Second Generation of HIV-1 Integrase Strand Transfer Inhibitors IT Raheem, AM Walji, D Klein, JM Sanders, DA Powell, P Abeywickrema, ... J. Med. Chem 59 (1), 486-486, 2016 | 38* | 2016 |