Sensitive enzymatic quantification of 5-hydroxymethylcytosine in genomic DNA A Szwagierczak, S Bultmann, CS Schmidt, F Spada, H Leonhardt Nucleic acids research 38 (19), e181-e181, 2010 | 519 | 2010 |
TREM 2 deficiency impairs chemotaxis and microglial responses to neuronal injury F Mazaheri, N Snaidero, G Kleinberger, C Madore, A Daria, G Werner, ... EMBO reports 18 (7), 1186-1198, 2017 | 320 | 2017 |
Targeted transcriptional activation of silent oct4 pluripotency gene by combining designer TALEs and inhibition of epigenetic modifiers S Bultmann, R Morbitzer, CS Schmidt, K Thanisch, F Spada, J Elsaesser, ... Nucleic acids research 40 (12), 5368-5377, 2012 | 300 | 2012 |
Recognition of 5-hydroxymethylcytosine by the Uhrf1 SRA domain C Frauer, T Hoffmann, S Bultmann, V Casa, MC Cardoso, I Antes, ... PloS one 6 (6), e21306, 2011 | 241 | 2011 |
Np95 interacts with de novo DNA methyltransferases, Dnmt3a and Dnmt3b, and mediates epigenetic silencing of the viral CMV promoter in embryonic stem cells D Meilinger, K Fellinger, S Bultmann, U Rothbauer, IM Bonapace, ... EMBO reports 10 (11), 1259-1264, 2009 | 228 | 2009 |
DNA methylation analysis on purified neurons and glia dissects age and Alzheimer’s disease-specific changes in the human cortex G Gasparoni, S Bultmann, P Lutsik, TFJ Kraus, S Sordon, J Vlcek, ... Epigenetics & chromatin 11, 1-19, 2018 | 198 | 2018 |
Visualization of specific DNA sequences in living mouse embryonic stem cells with a programmable fluorescent CRISPR/Cas system T Anton, S Bultmann, H Leonhardt, Y Markaki Nucleus 5 (2), 163-172, 2014 | 191 | 2014 |
Different binding properties and function of CXXC zinc finger domains in Dnmt1 and Tet1 C Frauer, A Rottach, D Meilinger, S Bultmann, K Fellinger, S Hasenöder, ... PloS one 6 (2), e16627, 2011 | 140 | 2011 |
The poly (ADP-ribose)-dependent chromatin remodeler Alc1 induces local chromatin relaxation upon DNA damage H Sellou, T Lebeaupin, C Chapuis, R Smith, A Hegele, HR Singh, ... Molecular biology of the cell 27 (24), 3791-3799, 2016 | 120 | 2016 |
The rRNA m6A methyltransferase METTL5 is involved in pluripotency and developmental programs VV Ignatova, P Stolz, S Kaiser, TH Gustafsson, PR Lastres, ... Genes & development 34 (9-10), 715-729, 2020 | 111 | 2020 |
Two distinct modes of DNMT1 recruitment ensure stable maintenance DNA methylation A Nishiyama, CB Mulholland, S Bultmann, S Kori, A Endo, Y Saeki, W Qin, ... Nature communications 11 (1), 1222, 2020 | 102 | 2020 |
Opposite microglial activation stages upon loss of PGRN or TREM 2 result in reduced cerebral glucose metabolism JK Götzl, M Brendel, G Werner, S Parhizkar, L Sebastian Monasor, ... EMBO molecular medicine 11 (6), e9711, 2019 | 100 | 2019 |
Growth hormone receptor-deficient pigs resemble the pathophysiology of human Laron syndrome and reveal altered activation of signaling cascades in the liver A Hinrichs, B Kessler, M Kurome, A Blutke, E Kemter, M Bernau, ... Molecular metabolism 11, 113-128, 2018 | 89 | 2018 |
Staying true to yourself: mechanisms of DNA methylation maintenance in mammals N Petryk, S Bultmann, T Bartke, PA Defossez Nucleic acids research 49 (6), 3020-3032, 2021 | 86 | 2021 |
Targeting and tracing of specific DNA sequences with dTALEs in living cells K Thanisch, K Schneider, R Morbitzer, I Solovei, T Lahaye, S Bultmann, ... Nucleic acids research 42 (6), e38-e38, 2014 | 81 | 2014 |
Loss of KDM6A confers drug resistance in acute myeloid leukemia SM Stief, AL Hanneforth, S Weser, R Mattes, M Carlet, WH Liu, ... Leukemia 34 (1), 50-62, 2020 | 80 | 2020 |
Critical role of the UBL domain in stimulating the E3 ubiquitin ligase activity of UHRF1 toward chromatin BM Foster, P Stolz, CB Mulholland, A Montoya, H Kramer, S Bultmann, ... Molecular cell 72 (4), 739-752. e9, 2018 | 79 | 2018 |
Spatial organization of transcribed eukaryotic genes S Leidescher, J Ribisel, S Ullrich, Y Feodorova, E Hildebrand, A Galitsyna, ... Nature cell biology 24 (3), 327-339, 2022 | 74 | 2022 |
Characterization of PvuRts1I endonuclease as a tool to investigate genomic 5–hydroxymethylcytosine A Szwagierczak, A Brachmann, CS Schmidt, S Bultmann, H Leonhardt, ... Nucleic acids research 39 (12), 5149-5156, 2011 | 69 | 2011 |
Genomic 5-hydroxymethylcytosine levels correlate with TET2 mutations and a distinct global gene expression pattern in secondary acute myeloid leukemia N Konstandin, S Bultmann, A Szwagierczak, A Dufour, B Ksienzyk, ... Leukemia 25 (10), 1649-1652, 2011 | 68 | 2011 |