| How does p53 induce apoptosis and how does this relate to p53-mediated tumour suppression? BJ Aubrey, GL Kelly, A Janic, MJ Herold, A Strasser Cell Death & Differentiation 25 (1), 104-113, 2018 | 1363 | 2018 |
| p53 efficiently suppresses tumor development in the complete absence of its cell-cycle inhibitory and proapoptotic effectors p21, Puma, and Noxa LJ Valente, DHD Gray, EM Michalak, J Pinon-Hofbauer, A Egle, CL Scott, ... Cell reports 3 (5), 1339-1345, 2013 | 335 | 2013 |
| Ectopic expression of germline genes drives malignant brain tumor growth in Drosophila A Janic, L Mendizabal, S Llamazares, D Rossell, C Gonzalez Science 330 (6012), 1824-1827, 2010 | 318 | 2010 |
| Apoptotic cell death in disease—Current understanding of the NCCD 2023 I Vitale, F Pietrocola, E Guilbaud, SA Aaronson, JM Abrams, D Adam, ... Cell Death & Differentiation 30 (5), 1097-1154, 2023 | 187 | 2023 |
| DNA repair processes are critical mediators of p53-dependent tumor suppression A Janic, LJ Valente, MJ Wakefield, L Di Stefano, L Milla, S Wilcox, H Yang, ... Nature medicine 24 (7), 947-953, 2018 | 152 | 2018 |
| Polyhomeotic has a tumor suppressor activity mediated by repression of Notch signaling AM Martinez, B Schuettengruber, S Sakr, A Janic, C Gonzalez, G Cavalli Nature genetics 41 (10), 1076-1082, 2009 | 142 | 2009 |
| Mutant TRP53 exerts a target gene-selective dominant-negative effect to drive tumor development BJ Aubrey, A Janic, Y Chen, C Chang, EC Lieschke, ST Diepstraten, ... Genes & Development 32 (21-22), 1420-1429, 2018 | 37 | 2018 |
| Combined loss of PUMA and p21 accelerates c-MYC-driven lymphoma development considerably less than loss of one allele of p53 LJ Valente, S Grabow, CJ Vandenberg, A Strasser, A Janic Oncogene 35 (29), 3866-3871, 2016 | 37 | 2016 |
| A metabolic map of the DNA damage response identifies PRDX1 in the control of nuclear ROS scavenging and aspartate availability A Moretton, S Kourtis, A Gañez Zapater, C Calabrò, ML Espinar Calvo, ... Molecular Systems Biology 19 (7), e11267, 2023 | 15 | 2023 |
| Consequences of Zmat3 loss in c-MYC- and mutant KRAS-driven tumorigenesis SA Best, CJ Vandenberg, E Abad, L Whitehead, L Guiu, S Ding, ... Cell Death & Disease 11 (10), 877, 2020 | 11 | 2020 |
| Combined absence of TRP53 target genes ZMAT3, PUMA and p21 cause a high incidence of cancer in mice A Janic, A Strasser, M Herold, MS Brennan, G Healey, L Gangoda, ... Cell Death and Diffrentiation, 2022 | 8* | 2022 |
| Decoding p53 tumor suppression: a crosstalk between genomic stability and epigenetic control? A Janic, E Abad, I Amelio Cell Death & Differentiation, 1-8, 2024 | 6 | 2024 |
| The TP53-activated E3 ligase RNF144B is a tumour suppressor that prevents genomic instability A Janic, E Abad, J Sandoz, G Romero, J Urgel-Solas, P Borredat, ... | | 2023 |
| Adaptation to ARF6-depletion in KRAS-driven PDAC is abolished by targeting TLR2 R Ghose, S Das, J Urgel-Solas, F Pezzano, D Datta, U Ghose, ... bioRxiv, 2023.11. 30.569405, 2023 | | 2023 |
| Finding critical cancer driving and cancer suppressing genes using functional genomics screening in vivo MJ Herold, S Mizutani, Y Deng, A Janic, A Kueh, M Pal, S Wilcox, L Tai, ... Cancer Research 80 (16_Supplement), 3427-3427, 2020 | | 2020 |
| Mutant p53 Enhances the Development and Sustained Growth of MYC-Driven Lymphoma and Exerts a Dominant Negative Effect Preferentially Deregulating Pathways for Metabolism and … BJ Aubrey, A Janic, Y Chen, GK Smyth, AJ Kueh, S Wilcox, MS Brennan, ... Blood 128 (22), 1545-1545, 2016 | | 2016 |
| Stimulating p53 down-under: a report from the 1st Australian p53 Workshop PM Neilsen, AW Braithwaite, C Gamell, S Haupt, A Janic, A Strasser, ... Cell death and differentiation 20 (12), 1753, 2013 | | 2013 |
